ID A0A3Q4G7M2_NEOBR Unreviewed; 2161 AA.
AC A0A3Q4G7M2;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 10-FEB-2021, entry version 12.
DE SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSNBRP00000004735};
OS Neolamprologus brichardi (Fairy cichlid) (Lamprologus brichardi).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Lamprologini; Neolamprologus.
OX NCBI_TaxID=32507 {ECO:0000313|Ensembl:ENSNBRP00000004735, ECO:0000313|Proteomes:UP000261580};
RN [1] {ECO:0000313|Ensembl:ENSNBRP00000004735}
RP NUCLEOTIDE SEQUENCE.
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lindblad-Toh K.;
RL Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSNBRP00000004735}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=25186727; DOI=10.1038/nature13726;
RA Brawand D., Wagner C.E., Li Y.I., Malinsky M., Keller I., Fan S.,
RA Simakov O., Ng A.Y., Lim Z.W., Bezault E., Turner-Maier J., Johnson J.,
RA Alcazar R., Noh H.J., Russell P., Aken B., Alfoldi J., Amemiya C.,
RA Azzouzi N., Baroiller J.F., Barloy-Hubler F., Berlin A., Bloomquist R.,
RA Carleton K.L., Conte M.A., D'Cotta H., Eshel O., Gaffney L., Galibert F.,
RA Gante H.F., Gnerre S., Greuter L., Guyon R., Haddad N.S., Haerty W.,
RA Harris R.M., Hofmann H.A., Hourlier T., Hulata G., Jaffe D.B., Lara M.,
RA Lee A.P., MacCallum I., Mwaiko S., Nikaido M., Nishihara H.,
RA Ozouf-Costaz C., Penman D.J., Przybylski D., Rakotomanga M., Renn S.C.P.,
RA Ribeiro F.J., Ron M., Salzburger W., Sanchez-Pulido L., Santos M.E.,
RA Searle S., Sharpe T., Swofford R., Tan F.J., Williams L., Young S., Yin S.,
RA Okada N., Kocher T.D., Miska E.A., Lander E.S., Venkatesh B., Fernald R.D.,
RA Meyer A., Ponting C.P., Streelman J.T., Lindblad-Toh K., Seehausen O.,
RA Di Palma F.;
RT "The genomic substrate for adaptive radiation in African cichlid fish.";
RL Nature 513:375-381(2014).
RN [3] {ECO:0000313|Ensembl:ENSNBRP00000004735}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (JAN-2019) to UniProtKB.
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DR Ensembl; ENSNBRT00000004878; ENSNBRP00000004735; ENSNBRG00000003597.
DR GeneTree; ENSGT00730000111187; -.
DR Proteomes; UP000261580; Unplaced.
DR GO; GO:0000775; C:chromosome, centromeric region; IEA:InterPro.
DR GO; GO:0070840; F:dynein complex binding; IEA:InterPro.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR GO; GO:0042803; F:protein homodimerization activity; IEA:InterPro.
DR GO; GO:0008134; F:transcription factor binding; IEA:InterPro.
DR InterPro; IPR043513; Cenp-F.
DR InterPro; IPR018302; CenpF/LEK1_Rb-prot-bd.
DR InterPro; IPR019513; Centromere_CenpF_leu-rich_rpt.
DR InterPro; IPR018463; Centromere_CenpF_N.
DR PANTHER; PTHR18874; PTHR18874; 5.
DR Pfam; PF10490; CENP-F_C_Rb_bdg; 1.
DR Pfam; PF10473; CENP-F_leu_zip; 2.
DR Pfam; PF10481; CENP-F_N; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000261580}.
FT DOMAIN 1..307
FT /note="CENP-F_N"
FT /evidence="ECO:0000259|Pfam:PF10481"
FT DOMAIN 1267..1409
FT /note="CENP-F_leu_zip"
FT /evidence="ECO:0000259|Pfam:PF10473"
FT DOMAIN 1505..1640
FT /note="CENP-F_leu_zip"
FT /evidence="ECO:0000259|Pfam:PF10473"
FT DOMAIN 2039..2083
FT /note="CENP-F_C_Rb_bdg"
FT /evidence="ECO:0000259|Pfam:PF10490"
FT REGION 120..141
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 222..281
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 448..521
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 768..788
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1661..1691
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1716..1753
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1776..1800
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1817..1859
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1952..2010
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2027..2051
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 20..82
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 167..197
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 529..559
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 564..605
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 624..651
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 685..705
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 713..747
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 801..831
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 923..950
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 961..1160
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1182..1209
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1271..1305
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1320..1368
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1390..1424
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1882..1926
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 259..281
FT /note="Polar"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 473..489
FT /note="Polyampholyte"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 501..515
FT /note="Polyampholyte"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1670..1691
FT /note="Polyampholyte"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1817..1848
FT /note="Polyampholyte"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1966..1985
FT /note="Polyampholyte"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1986..2001
FT /note="Polar"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2161 AA; 248451 MW; 90560D5457A570DA CRC64;
MSWAVEEWKD GLPGKALQKI QEMEVQLDKL KKEKTQKQFQ LDSLEAALQK QKQKVDSERT
ETSALKRENQ SLLESCDSLE KARQKVVHDL GVKEQQVSYL EGQLNSCRKT IERLEQELKK
HKNELDRSQP AGSSSLSSSS CELQTYATPQ KSFQTPASIP AYRQHGIKIL EELQEKYNQE
VEERKRLESE LKVLQVKLLN QSSVSVSHKD IAARQAGSSI FPWQQQDSAH RRQSQDIMET
PLKRRGTSLW DAHEETPIKP SQRMSSSRAA PSPSGSSQQM EQLKTLNQEL RGHVSELERN
LANQEKEIRN QASKLQELQT QLNQARKDLS ERDRDLTKAK HELSQATDRH QQVESKCSSV
EQKLKQVTEE MSCQRHNAES CRRALEQKLK DQERDSQKEL AQLQSSHHAL DQQLNQTRTK
LTQEIQQAKK DHNILQADME KMCFQKKQME KEMEEQKQKL LRSEQSLQAC QTKEQDLRKK
MEELQKEKNS MTVQLDQSNR RLSQLEEEKK SSNQKGEKAS LSAHIDSLKG ELLNKCTDLE
EKAHQYKELQ SQFSEAGQKH AKDLENIGVQ VAQLEAQVKD LELRLQKEIT RAELAERMNT
DLQDEHKATC DLVRSKEQLV ELGRAEISQL RESLAQTIAQ QEEQNARWDQ TEKIHSLLEQ
ISSLEEKVDV NKDAAEKLPV LKNELDVATQ SNSDLKKSLQ ALEKNHSSTI EIKSNLESTL
VEKMNLISAL ENEVKDLIEK MGKESERHAL EIENFLKKEK SLDEQLEATK KSVSAAKAES
SSRREEIRTM KATLSAASRG LEERDSTIKD LKEKLNKAEA EQTKASELLK EKVVAMNKIK
VGAKCVPVYV LVYYNILRHK ESVLLDSVAN LLVACSELLI IPLQTIKVQL EMLQMDLEDN
ETAMTSFDSQ VEQLKGTIES LEVSVLEARL DEVQSQNSLL ESKYVTAKEE LFERTCEITR
LEEEAIRRHE LEENNEKLET TLRETIQDKE SSLNQLLQEK NNLETSLKQL MNDKEQVEGE
MVHVNAEKKL LEVTVDALSE ENKQLQSNIE QVTEEKQQTE AKINEITARK HEAESALSQL
TEAKAQLDDI LKKTNEENVQ LADELHALTS EKNDLVTKLN QVVEEKVQLE LSYNQLSEEN
IKLQSNVNQI TEEKLQLQEL IKGHGDGVAS LREENECIQH SLLTSEQERQ RLKEQLELME
ERTEATNKEQ YVYMAVSALK FVLAFELFLT QLSEEKETLT LQLQTTKFQL TDVMEMLEGL
EMAKGGWDEK FLQQESELKR VRSEKANLEQ HILGMESELE TMQAEGARLK GEMETQRRTF
SGMEQKIETL ITEVSKLRSE LVSCTEERDE LSQSLSQWRE KVHSLEKNNC DTRNLISILE
DDIRAGRKEY EALQSSTNKL KTERQQLVEQ VKELEQTISQ HCGEREELIG HLNQIKEDHS
SSNQNTESMA GKIKALEGEV FRLSQSLESS LLEKGEIASR LNSTQDEVQQ MRTGIEKLQV
RIESDERKKK KMGELLKAAQ RKSDSLQDRI DSLEREKEDV EQSLEEAVLQ AETAKAELEE
ERRMLSAKIS ELSTTLESLR SEKEHMERQL EIKNREIEEL KAAKEELERG LEKAEAERKE
EEERQKCRLE ELEKEMKGEA ERQIRVLDDL QAQLEEKKHL LSSLQESQTE GEKLRSHGEE
WETERNSLRT QTEALEEEIE ELKILIKTTG DKMEVLEKEK EEDRDQKQAL ERSISSVMAE
KEEIEGENGR LVQEKEELRT ALLSLEQERD QLRSSLLSVE DEKERLDQGR SALASEREEL
QSRLSLLDKE KHDLQQKLSF LNQEKEREEE EKQKIEAEKQ ELKSSVSLME EEKNNLSSAL
LSLEQEKETL SQEKDQEVNK LSAALDGKRK EFEEKVKELE EMKTELEEVN KLLEEKSKEA
DESMEKYCSL MLEVHKLEKT NEALKTRLEL IGASQNANDS HSSSTEGHQR SGRKSSTRHQ
EIKIDNNTEN IAPSTTHRSP PGSGKRGHCE ISNRDSAQEA LHNVTKRIKA NATTTPKSRP
EQEDEEFRPE GLPELVQRGF ADIPLGEASP FIIRRTTVRR CSPRLAAKQT ASDGKVSNTG
ISIFFTDTAW CSVFCYLFPL VSFTSHTLNG HFIVKCSPSS RKTPEKQLRE QTQQGDNCHV
Q
//
