GenomeNet

Database: UniProt
Entry: A0A3Q4G7M2_NEOBR
LinkDB: A0A3Q4G7M2_NEOBR
Original site: A0A3Q4G7M2_NEOBR 
ID   A0A3Q4G7M2_NEOBR        Unreviewed;      2161 AA.
AC   A0A3Q4G7M2;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   10-FEB-2021, entry version 12.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSNBRP00000004735};
OS   Neolamprologus brichardi (Fairy cichlid) (Lamprologus brichardi).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Lamprologini; Neolamprologus.
OX   NCBI_TaxID=32507 {ECO:0000313|Ensembl:ENSNBRP00000004735, ECO:0000313|Proteomes:UP000261580};
RN   [1] {ECO:0000313|Ensembl:ENSNBRP00000004735}
RP   NUCLEOTIDE SEQUENCE.
RA   Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA   MacCallum I., Young S., Walker B.J., Lindblad-Toh K.;
RL   Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSNBRP00000004735}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=25186727; DOI=10.1038/nature13726;
RA   Brawand D., Wagner C.E., Li Y.I., Malinsky M., Keller I., Fan S.,
RA   Simakov O., Ng A.Y., Lim Z.W., Bezault E., Turner-Maier J., Johnson J.,
RA   Alcazar R., Noh H.J., Russell P., Aken B., Alfoldi J., Amemiya C.,
RA   Azzouzi N., Baroiller J.F., Barloy-Hubler F., Berlin A., Bloomquist R.,
RA   Carleton K.L., Conte M.A., D'Cotta H., Eshel O., Gaffney L., Galibert F.,
RA   Gante H.F., Gnerre S., Greuter L., Guyon R., Haddad N.S., Haerty W.,
RA   Harris R.M., Hofmann H.A., Hourlier T., Hulata G., Jaffe D.B., Lara M.,
RA   Lee A.P., MacCallum I., Mwaiko S., Nikaido M., Nishihara H.,
RA   Ozouf-Costaz C., Penman D.J., Przybylski D., Rakotomanga M., Renn S.C.P.,
RA   Ribeiro F.J., Ron M., Salzburger W., Sanchez-Pulido L., Santos M.E.,
RA   Searle S., Sharpe T., Swofford R., Tan F.J., Williams L., Young S., Yin S.,
RA   Okada N., Kocher T.D., Miska E.A., Lander E.S., Venkatesh B., Fernald R.D.,
RA   Meyer A., Ponting C.P., Streelman J.T., Lindblad-Toh K., Seehausen O.,
RA   Di Palma F.;
RT   "The genomic substrate for adaptive radiation in African cichlid fish.";
RL   Nature 513:375-381(2014).
RN   [3] {ECO:0000313|Ensembl:ENSNBRP00000004735}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JAN-2019) to UniProtKB.
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DR   Ensembl; ENSNBRT00000004878; ENSNBRP00000004735; ENSNBRG00000003597.
DR   GeneTree; ENSGT00730000111187; -.
DR   Proteomes; UP000261580; Unplaced.
DR   GO; GO:0000775; C:chromosome, centromeric region; IEA:InterPro.
DR   GO; GO:0070840; F:dynein complex binding; IEA:InterPro.
DR   GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR   GO; GO:0042803; F:protein homodimerization activity; IEA:InterPro.
DR   GO; GO:0008134; F:transcription factor binding; IEA:InterPro.
DR   InterPro; IPR043513; Cenp-F.
DR   InterPro; IPR018302; CenpF/LEK1_Rb-prot-bd.
DR   InterPro; IPR019513; Centromere_CenpF_leu-rich_rpt.
DR   InterPro; IPR018463; Centromere_CenpF_N.
DR   PANTHER; PTHR18874; PTHR18874; 5.
DR   Pfam; PF10490; CENP-F_C_Rb_bdg; 1.
DR   Pfam; PF10473; CENP-F_leu_zip; 2.
DR   Pfam; PF10481; CENP-F_N; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000261580}.
FT   DOMAIN          1..307
FT                   /note="CENP-F_N"
FT                   /evidence="ECO:0000259|Pfam:PF10481"
FT   DOMAIN          1267..1409
FT                   /note="CENP-F_leu_zip"
FT                   /evidence="ECO:0000259|Pfam:PF10473"
FT   DOMAIN          1505..1640
FT                   /note="CENP-F_leu_zip"
FT                   /evidence="ECO:0000259|Pfam:PF10473"
FT   DOMAIN          2039..2083
FT                   /note="CENP-F_C_Rb_bdg"
FT                   /evidence="ECO:0000259|Pfam:PF10490"
FT   REGION          120..141
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          222..281
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          448..521
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          768..788
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1661..1691
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1716..1753
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1776..1800
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1817..1859
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1952..2010
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          2027..2051
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          20..82
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          167..197
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          529..559
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          564..605
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          624..651
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          685..705
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          713..747
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          801..831
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          923..950
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          961..1160
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1182..1209
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1271..1305
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1320..1368
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1390..1424
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1882..1926
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        259..281
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        473..489
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        501..515
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1670..1691
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1817..1848
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1966..1985
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1986..2001
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   2161 AA;  248451 MW;  90560D5457A570DA CRC64;
     MSWAVEEWKD GLPGKALQKI QEMEVQLDKL KKEKTQKQFQ LDSLEAALQK QKQKVDSERT
     ETSALKRENQ SLLESCDSLE KARQKVVHDL GVKEQQVSYL EGQLNSCRKT IERLEQELKK
     HKNELDRSQP AGSSSLSSSS CELQTYATPQ KSFQTPASIP AYRQHGIKIL EELQEKYNQE
     VEERKRLESE LKVLQVKLLN QSSVSVSHKD IAARQAGSSI FPWQQQDSAH RRQSQDIMET
     PLKRRGTSLW DAHEETPIKP SQRMSSSRAA PSPSGSSQQM EQLKTLNQEL RGHVSELERN
     LANQEKEIRN QASKLQELQT QLNQARKDLS ERDRDLTKAK HELSQATDRH QQVESKCSSV
     EQKLKQVTEE MSCQRHNAES CRRALEQKLK DQERDSQKEL AQLQSSHHAL DQQLNQTRTK
     LTQEIQQAKK DHNILQADME KMCFQKKQME KEMEEQKQKL LRSEQSLQAC QTKEQDLRKK
     MEELQKEKNS MTVQLDQSNR RLSQLEEEKK SSNQKGEKAS LSAHIDSLKG ELLNKCTDLE
     EKAHQYKELQ SQFSEAGQKH AKDLENIGVQ VAQLEAQVKD LELRLQKEIT RAELAERMNT
     DLQDEHKATC DLVRSKEQLV ELGRAEISQL RESLAQTIAQ QEEQNARWDQ TEKIHSLLEQ
     ISSLEEKVDV NKDAAEKLPV LKNELDVATQ SNSDLKKSLQ ALEKNHSSTI EIKSNLESTL
     VEKMNLISAL ENEVKDLIEK MGKESERHAL EIENFLKKEK SLDEQLEATK KSVSAAKAES
     SSRREEIRTM KATLSAASRG LEERDSTIKD LKEKLNKAEA EQTKASELLK EKVVAMNKIK
     VGAKCVPVYV LVYYNILRHK ESVLLDSVAN LLVACSELLI IPLQTIKVQL EMLQMDLEDN
     ETAMTSFDSQ VEQLKGTIES LEVSVLEARL DEVQSQNSLL ESKYVTAKEE LFERTCEITR
     LEEEAIRRHE LEENNEKLET TLRETIQDKE SSLNQLLQEK NNLETSLKQL MNDKEQVEGE
     MVHVNAEKKL LEVTVDALSE ENKQLQSNIE QVTEEKQQTE AKINEITARK HEAESALSQL
     TEAKAQLDDI LKKTNEENVQ LADELHALTS EKNDLVTKLN QVVEEKVQLE LSYNQLSEEN
     IKLQSNVNQI TEEKLQLQEL IKGHGDGVAS LREENECIQH SLLTSEQERQ RLKEQLELME
     ERTEATNKEQ YVYMAVSALK FVLAFELFLT QLSEEKETLT LQLQTTKFQL TDVMEMLEGL
     EMAKGGWDEK FLQQESELKR VRSEKANLEQ HILGMESELE TMQAEGARLK GEMETQRRTF
     SGMEQKIETL ITEVSKLRSE LVSCTEERDE LSQSLSQWRE KVHSLEKNNC DTRNLISILE
     DDIRAGRKEY EALQSSTNKL KTERQQLVEQ VKELEQTISQ HCGEREELIG HLNQIKEDHS
     SSNQNTESMA GKIKALEGEV FRLSQSLESS LLEKGEIASR LNSTQDEVQQ MRTGIEKLQV
     RIESDERKKK KMGELLKAAQ RKSDSLQDRI DSLEREKEDV EQSLEEAVLQ AETAKAELEE
     ERRMLSAKIS ELSTTLESLR SEKEHMERQL EIKNREIEEL KAAKEELERG LEKAEAERKE
     EEERQKCRLE ELEKEMKGEA ERQIRVLDDL QAQLEEKKHL LSSLQESQTE GEKLRSHGEE
     WETERNSLRT QTEALEEEIE ELKILIKTTG DKMEVLEKEK EEDRDQKQAL ERSISSVMAE
     KEEIEGENGR LVQEKEELRT ALLSLEQERD QLRSSLLSVE DEKERLDQGR SALASEREEL
     QSRLSLLDKE KHDLQQKLSF LNQEKEREEE EKQKIEAEKQ ELKSSVSLME EEKNNLSSAL
     LSLEQEKETL SQEKDQEVNK LSAALDGKRK EFEEKVKELE EMKTELEEVN KLLEEKSKEA
     DESMEKYCSL MLEVHKLEKT NEALKTRLEL IGASQNANDS HSSSTEGHQR SGRKSSTRHQ
     EIKIDNNTEN IAPSTTHRSP PGSGKRGHCE ISNRDSAQEA LHNVTKRIKA NATTTPKSRP
     EQEDEEFRPE GLPELVQRGF ADIPLGEASP FIIRRTTVRR CSPRLAAKQT ASDGKVSNTG
     ISIFFTDTAW CSVFCYLFPL VSFTSHTLNG HFIVKCSPSS RKTPEKQLRE QTQQGDNCHV
     Q
//
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