ID   A0A3Q4G800_NEOBR        Unreviewed;      1013 AA.
AC   A0A3Q4G800;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=Probable ATP-dependent RNA helicase DHX34-like {ECO:0000313|Ensembl:ENSNBRP00000004925.1};
OS   Neolamprologus brichardi (Fairy cichlid) (Lamprologus brichardi).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Lamprologini; Neolamprologus.
OX   NCBI_TaxID=32507 {ECO:0000313|Ensembl:ENSNBRP00000004925.1, ECO:0000313|Proteomes:UP000261580};
RN   [1] {ECO:0000313|Ensembl:ENSNBRP00000004925.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A3Q4G800; -.
DR   STRING; 32507.ENSNBRP00000004925; -.
DR   Ensembl; ENSNBRT00000005078.1; ENSNBRP00000004925.1; ENSNBRG00000003884.1.
DR   GeneTree; ENSGT00940000158721; -.
DR   OMA; CIFANSP; -.
DR   Proteomes; UP000261580; Unplaced.
DR   Bgee; ENSNBRG00000003884; Expressed in testis and 1 other cell type or tissue.
DR   GO; GO:0043009; P:chordate embryonic development; IEA:Ensembl.
DR   GO; GO:2000623; P:negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IEA:Ensembl.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IEA:Ensembl.
DR   CDD; cd17979; DEXHc_DHX34; 1.
DR   CDD; cd18791; SF2_C_RHA; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR011709; DEAD-box_helicase_OB_fold.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR   PANTHER; PTHR18934:SF148; ATP-DEPENDENT RNA HELICASE DHX34-RELATED; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   Pfam; PF07717; OB_NTP_bind; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022806};
KW   Helicase {ECO:0000256|ARBA:ARBA00022806};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022806};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022806};
KW   Reference proteome {ECO:0000313|Proteomes:UP000261580}.
FT   DOMAIN          163..323
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51192"
FT   DOMAIN          359..527
FT                   /note="Helicase C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51194"
FT   REGION          100..119
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          590..666
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        597..661
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1013 AA;  115424 MW;  6B5665FBF08D0782 CRC64;
     AGRKDLRKRS FISQCRAQLD EIFFREHDYI QAGSSEHKEF WAFFERFQRF KTKRDMSGAE
     IRKEDKGKGR DRGKVDLGLP KEYDARYRIN VSVCTRDIEE RMGKSEHRSR QRSSGPGAQE
     VSDCRLALLH FLDFSQKQSF GKIAKLRREQ KNLPIFQYRD RIVELVRIHP VVVVAGDTGC
     GKSTQVPQYL LSAGFDNIAC TQPRRIACIS LAKRVSFESL NQYGSKVGYQ IRFETSRTAA
     TKLLFLTEGL LLRQIQQDST LARYQVVIVD EVHERHLHCD FLLGVLRSLL ADRPDLRLIL
     MSATINIKLF SNYFSGAPVL QVPGRLFPIQ VIYQPIPPEE QSSKSEKLDP RPYLRILQGI
     DQRYPPEERG DLLLFLSGVA EISTIQEACQ IYATHTRRWI ILTLHSTLSI AQQDKVFDIA
     PPGVRKCIIS TNIAETSVTI DGVRFVVDSG KVKEMSFDPK AKMQRLQEFW ISRASSEQRK
     GRAGRTGPGV CYRLYSESDY NAFAPYPVPE IHRVALDSLI LQVIRFCEYN QGDPFTLLNT
     FNAWVEVKGE RGGGSRKWCR RRGLEEQRLY EMVNLRRQFK DLLRSHSLLE SEDSTPSGGD
     RVQRRERLTE RRKLHQLKRD HEQQEGSKRK VLRLEEGQEG DSSGSDTEET GRSKRNKEGS
     GQNLDIQEVK FKLRHNVSEL QEAVSQDLSS HQQALLKLLL CRGLYPQLAL PDEHNSTRKD
     SDQVFHTRNK QGVVIHPTSV FASDPEVLQV PEGDTGEMDS TKHQLLAFVT LLETNKPYLS
     NCVRVPALQA LLLVANSVDT NADCTRLVVD GWLELELKEP EEALKVLSTA LTLRAEWERL
     LQAQLGQNST GGAAAGQGVS RRVVQKLSES LVRFLLYTEV SYSLRRLSAF QTQNLYIGPQ
     SESVSSNTKA GDLNPLFPGA EAKPDPIKGG LRVTNFFTYN CLADSKDLYS ECLRTFWSCP
     NCDLYMPLTP LERMHHEASC RPAGEQQQPE EGQEFLLYSD WFDTLSVRPH TLF
//