ID A0A3Q4G8N7_NEOBR Unreviewed; 1960 AA.
AC A0A3Q4G8N7;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 10-FEB-2021, entry version 10.
DE SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSNBRP00000004746};
OS Neolamprologus brichardi (Fairy cichlid) (Lamprologus brichardi).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Lamprologini; Neolamprologus.
OX NCBI_TaxID=32507 {ECO:0000313|Ensembl:ENSNBRP00000004746, ECO:0000313|Proteomes:UP000261580};
RN [1] {ECO:0000313|Ensembl:ENSNBRP00000004746}
RP NUCLEOTIDE SEQUENCE.
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lindblad-Toh K.;
RL Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSNBRP00000004746}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=25186727; DOI=10.1038/nature13726;
RA Brawand D., Wagner C.E., Li Y.I., Malinsky M., Keller I., Fan S.,
RA Simakov O., Ng A.Y., Lim Z.W., Bezault E., Turner-Maier J., Johnson J.,
RA Alcazar R., Noh H.J., Russell P., Aken B., Alfoldi J., Amemiya C.,
RA Azzouzi N., Baroiller J.F., Barloy-Hubler F., Berlin A., Bloomquist R.,
RA Carleton K.L., Conte M.A., D'Cotta H., Eshel O., Gaffney L., Galibert F.,
RA Gante H.F., Gnerre S., Greuter L., Guyon R., Haddad N.S., Haerty W.,
RA Harris R.M., Hofmann H.A., Hourlier T., Hulata G., Jaffe D.B., Lara M.,
RA Lee A.P., MacCallum I., Mwaiko S., Nikaido M., Nishihara H.,
RA Ozouf-Costaz C., Penman D.J., Przybylski D., Rakotomanga M., Renn S.C.P.,
RA Ribeiro F.J., Ron M., Salzburger W., Sanchez-Pulido L., Santos M.E.,
RA Searle S., Sharpe T., Swofford R., Tan F.J., Williams L., Young S., Yin S.,
RA Okada N., Kocher T.D., Miska E.A., Lander E.S., Venkatesh B., Fernald R.D.,
RA Meyer A., Ponting C.P., Streelman J.T., Lindblad-Toh K., Seehausen O.,
RA Di Palma F.;
RT "The genomic substrate for adaptive radiation in African cichlid fish.";
RL Nature 513:375-381(2014).
RN [3] {ECO:0000313|Ensembl:ENSNBRP00000004746}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (JAN-2019) to UniProtKB.
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DR Ensembl; ENSNBRT00000004889; ENSNBRP00000004746; ENSNBRG00000003597.
DR GeneTree; ENSGT00730000111187; -.
DR OMA; YNAQLVQ; -.
DR Proteomes; UP000261580; Unplaced.
DR GO; GO:0000775; C:chromosome, centromeric region; IEA:InterPro.
DR GO; GO:0070840; F:dynein complex binding; IEA:InterPro.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR GO; GO:0042803; F:protein homodimerization activity; IEA:InterPro.
DR GO; GO:0008134; F:transcription factor binding; IEA:InterPro.
DR InterPro; IPR043513; Cenp-F.
DR InterPro; IPR018302; CenpF/LEK1_Rb-prot-bd.
DR InterPro; IPR019513; Centromere_CenpF_leu-rich_rpt.
DR InterPro; IPR018463; Centromere_CenpF_N.
DR PANTHER; PTHR18874; PTHR18874; 5.
DR Pfam; PF10490; CENP-F_C_Rb_bdg; 1.
DR Pfam; PF10473; CENP-F_leu_zip; 2.
DR Pfam; PF10481; CENP-F_N; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000261580}.
FT DOMAIN 1..307
FT /note="CENP-F_N"
FT /evidence="ECO:0000259|Pfam:PF10481"
FT DOMAIN 1066..1208
FT /note="CENP-F_leu_zip"
FT /evidence="ECO:0000259|Pfam:PF10473"
FT DOMAIN 1304..1439
FT /note="CENP-F_leu_zip"
FT /evidence="ECO:0000259|Pfam:PF10473"
FT DOMAIN 1838..1882
FT /note="CENP-F_C_Rb_bdg"
FT /evidence="ECO:0000259|Pfam:PF10490"
FT REGION 120..141
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 222..281
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 448..521
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 768..788
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1460..1490
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1515..1552
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1573..1599
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1616..1658
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1751..1809
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1826..1850
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 20..82
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 167..197
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 529..559
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 564..605
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 624..651
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 685..705
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 713..747
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 801..831
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 904..945
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 965..1041
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1070..1104
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1119..1167
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1189..1223
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1681..1725
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 259..281
FT /note="Polar"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 473..489
FT /note="Polyampholyte"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 501..515
FT /note="Polyampholyte"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1469..1490
FT /note="Polyampholyte"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1616..1647
FT /note="Polyampholyte"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1765..1784
FT /note="Polyampholyte"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1785..1800
FT /note="Polar"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1960 AA; 225330 MW; 872F63DE8C41E74A CRC64;
MSWAVEEWKD GLPGKALQKI QEMEVQLDKL KKEKTQKQFQ LDSLEAALQK QKQKVDSERT
ETSALKRENQ SLLESCDSLE KARQKVVHDL GVKEQQVSYL EGQLNSCRKT IERLEQELKK
HKNELDRSQP AGSSSLSSSS CELQTYATPQ KSFQTPASIP AYRQHGIKIL EELQEKYNQE
VEERKRLESE LKVLQVKLLN QSSVSVSHKD IAARQAGSSI FPWQQQDSAH RRQSQDIMET
PLKRRGTSLW DAHEETPIKP SQRMSSSRAA PSPSGSSQQM EQLKTLNQEL RGHVSELERN
LANQEKEIRN QASKLQELQT QLNQARKDLS ERDRDLTKAK HELSQATDRH QQVESKCSSV
EQKLKQVTEE MSCQRHNAES CRRALEQKLK DQERDSQKEL AQLQSSHHAL DQQLNQTRTK
LTQEIQQAKK DHNILQADME KMCFQKKQME KEMEEQKQKL LRSEQSLQAC QTKEQDLRKK
MEELQKEKNS MTVQLDQSNR RLSQLEEEKK SSNQKGEKAS LSAHIDSLKG ELLNKCTDLE
EKAHQYKELQ SQFSEAGQKH AKDLENIGVQ VAQLEAQVKD LELRLQKEIT RAELAERMNT
DLQDEHKATC DLVRSKEQLV ELGRAEISQL RESLAQTIAQ QEEQNARWDQ TEKIHSLLEQ
ISSLEEKVDV NKDAAEKLPV LKNELDVATQ SNSDLKKSLQ ALEKNHSSTI EIKSNLESTL
VEKMNLISAL ENEVKDLIEK MGKESERHAL EIENFLKKEK SLDEQLEATK KSVSAAKAES
SSRREEIRTM KATLSAASRG LEERDSTIKD LKEKLNKAEA EQTKASELLK EKVVAMNKIK
VGAKCVPVYV LVYYNILRHK ESVLLDSVAN LLVACSELLI IPLQTIKVQL EMLQMDLEDN
ETAMTSFDSQ VEQLKGTIES LEAMLAQSQT QMSEMEAMLD EGRAQLRLNI NIQMAFRHIC
PSTESSLVND ELERYKEMIR KQEKELETLR SEFDLLSSDL ELRKELTSEL EVQVQNLEQK
VHAAEEELTQ LSEEKETLTL QLQTTKFQLT DVMEMLEGLE MAKGGWDEKF LQQESELKRV
RSEKANLEQH ILGMESELET MQAEGARLKG EMETQRRTFS GMEQKIETLI TEVSKLRSEL
VSCTEERDEL SQSLSQWREK VHSLEKNNCD TRNLISILED DIRAGRKEYE ALQSSTNKLK
TERQQLVEQV KELEQTISQH CGEREELIGH LNQIKEDHSS SNQNTESMAG KIKALEGEVF
RLSQSLESSL LEKGEIASRL NSTQDEVQQM RTGIEKLQVR IESDERKKKK MGELLKAAQR
KSDSLQDRID SLEREKEDVE QSLEEAVLQA ETAKAELEEE RRMLSAKISE LSTTLESLRS
EKEHMERQLE IKNREIEELK AAKEELERGL EKAEAERKEE EERQKCRLEE LEKEMKGEAE
RQIRVLDDLQ AQLEEKKHLL SSLQESQTEG EKLRSHGEEW ETERNSLRTQ TEALEEEIEE
LKILIKTTGD KMEVLEKEKE EDRDQKQALE RSISSVMAEK EEIEGENGRL VQEKEELRTA
LLSLEQERDQ LRSSLLSVED EKERLDQGRS ALASEREELQ SRLSLLDKEK HDLQQKLSFL
NQEKEREEEE KQKIEAEKQE LKSSVSLMEE EKNNLSSALL SLEQEKETLS QEKDQEVNKL
SAALDGKRKE FEEKVKELEE MKTELEEVNK LLEEKSKEAD ESMEKYCSLM LEVHKLEKTN
EALKTRLELI GASQNANDSH SSSTEGHQRS GRKSSTRHQE IKIDNNTENI APSTTHRSPP
GSGKRGHCEI SNRDSAQEAL HNVTKRIKAN ATTTPKSRPE QEDEEFRPEG LPELVQRGFA
DIPLGEASPF IIRRTTVRRC SPRLAAKQTA SDGKVSNTGI SIFFTDTAWC SVFCYLFPLV
SFTSHTLNGH FIVKCSPSSR KTPEKQLREQ TQQGDNCHVQ
//
