ID   A0A3Q4GAG0_NEOBR        Unreviewed;       958 AA.
AC   A0A3Q4GAG0;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=Delphilin-like {ECO:0000313|Ensembl:ENSNBRP00000003358.1};
GN   Name=GRID2IP {ECO:0000313|Ensembl:ENSNBRP00000003358.1};
OS   Neolamprologus brichardi (Fairy cichlid) (Lamprologus brichardi).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Lamprologini; Neolamprologus.
OX   NCBI_TaxID=32507 {ECO:0000313|Ensembl:ENSNBRP00000003358.1, ECO:0000313|Proteomes:UP000261580};
RN   [1] {ECO:0000313|Ensembl:ENSNBRP00000003358.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A3Q4GAG0; -.
DR   STRING; 32507.ENSNBRP00000003358; -.
DR   Ensembl; ENSNBRT00000003477.1; ENSNBRP00000003358.1; ENSNBRG00000002647.1.
DR   GeneTree; ENSGT00940000157625; -.
DR   OMA; CENVPPS; -.
DR   Proteomes; UP000261580; Unplaced.
DR   Bgee; ENSNBRG00000002647; Expressed in brain.
DR   CDD; cd07355; HN_L-delphilin-R2_like; 1.
DR   CDD; cd00992; PDZ_signaling; 1.
DR   Gene3D; 1.20.1160.20; -; 1.
DR   Gene3D; 2.30.42.10; -; 1.
DR   Gene3D; 1.20.58.2220; Formin, FH2 domain; 1.
DR   InterPro; IPR015425; FH2_Formin.
DR   InterPro; IPR042201; FH2_Formin_sf.
DR   InterPro; IPR001478; PDZ.
DR   InterPro; IPR036034; PDZ_sf.
DR   PANTHER; PTHR45725:SF13; DELPHILIN-LIKE ISOFORM X1; 1.
DR   PANTHER; PTHR45725; FORMIN HOMOLOGY 2 FAMILY MEMBER; 1.
DR   Pfam; PF02181; FH2; 1.
DR   Pfam; PF00595; PDZ; 1.
DR   SMART; SM00498; FH2; 1.
DR   SMART; SM00228; PDZ; 1.
DR   SUPFAM; SSF101447; Formin homology 2 domain (FH2 domain); 1.
DR   SUPFAM; SSF50156; PDZ domain-like; 1.
DR   PROSITE; PS51444; FH2; 1.
DR   PROSITE; PS50106; PDZ; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000261580}.
FT   DOMAIN          89..166
FT                   /note="PDZ"
FT                   /evidence="ECO:0000259|PROSITE:PS50106"
FT   DOMAIN          563..957
FT                   /note="FH2"
FT                   /evidence="ECO:0000259|PROSITE:PS51444"
FT   REGION          27..66
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          348..423
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          446..566
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        32..53
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        365..384
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        385..402
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        446..464
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        475..500
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        501..531
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        538..562
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   958 AA;  107172 MW;  4DDCED3C760AD8FC CRC64;
     MFVRIFIPKK HRERFDEVVS QSLMSRLKGR SFSDPSRSHL RRSRSEDHPE RLLVSTRASS
     VPRTHAEEGV VPPARGMRKT TSLIAGHSSV RVCKGNMSFG FTLRGHAPVW IDSVIPGSPA
     DKAGLKPGDR ILFLNGLDMR TSSHEKVVSM LQGSGAMPTL VVEDGPPTFT LAEQDLAGGG
     VPTERARSPV LSSLQWVAEI LPPSIRVQGR TFGQQLEHLL TIQERYTICK ALENFFQHRN
     VDTLIVDVFP VLDTPAKQVI WQFVYQLLTY EEQEHCQSKI SRFLGYKSPG KCHRAEPLLE
     TGMRLAPGER QSGDGTSLPE TPNNLTNVHS AVIITTYHFL VLGSRKGPSS HTSWPEPLPS
     PPQSQFYPSG LTSQTSGESN PYISLDSPPP SPPEPPDYPS SPPAHRSSKR RYTFSKPPRS
     EDTDRFLDAL SEQLGQRVAI VDDFLTPEND YEEDNEDDLV VDEEESGGFV APELSSPSDV
     QSSSGEENAS SLTYSSSSDH IPPPPMTPPP PPPVQFNDPP PPPPPPQLSY TPEHSPRTYH
     LEPPPPPPLP PPCSPPPLPR PSLSRMDSNH MSVKRLRWEQ VENSEGTIWG QLGANSDYEK
     LHDMVKYLDL ELHFGTQKSA KPCPQLETFK KKDVIEILSH KKAYNASILI AHLKLSPGEL
     RQILMNMATD RLEPAHIKQL LLYAPDAEEI KKYEEYRQDP SKLSEPDQFV LQMLSVPEYQ
     TRLQCLLFKC SLQEKTEELK GAYDCIYNAS MELKTSKKLA KILEFVLAMG NYLNNSQPKT
     NKTTGFKINF LTELSTTKTV DGKSTFLHIL VKSLCQHFPD VLDFSKDLTM HLFPLASVNQ
     RNITSDLNDL HTTIQEIRSA CQKMPATSED RFAVVMSNFL ENSHPAIQSL ESLQQRAMEE
     FSKTASYFGE DGKATNTEAF FGIFAEFINK FERALSDQQV AEIPKSPRSP RMASPLAW
//