ID A0A3Q4GAP3_NEOBR Unreviewed; 354 AA.
AC A0A3Q4GAP3;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE SubName: Full=Guanine nucleotide-binding protein G(i) subunit alpha-1-like {ECO:0000313|Ensembl:ENSNBRP00000003458.1};
OS Neolamprologus brichardi (Fairy cichlid) (Lamprologus brichardi).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Lamprologini; Neolamprologus.
OX NCBI_TaxID=32507 {ECO:0000313|Ensembl:ENSNBRP00000003458.1, ECO:0000313|Proteomes:UP000261580};
RN [1] {ECO:0000313|Ensembl:ENSNBRP00000003458.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR RefSeq; XP_006789577.1; XM_006789514.1.
DR RefSeq; XP_006789578.1; XM_006789515.1.
DR AlphaFoldDB; A0A3Q4GAP3; -.
DR STRING; 32507.ENSNBRP00000003458; -.
DR Ensembl; ENSNBRT00000003578.1; ENSNBRP00000003458.1; ENSNBRG00000002767.1.
DR GeneID; 102785689; -.
DR GeneTree; ENSGT00940000153567; -.
DR OMA; EKTMGCT; -.
DR OrthoDB; 2897309at2759; -.
DR Proteomes; UP000261580; Unplaced.
DR Bgee; ENSNBRG00000002767; Expressed in mesonephros and 9 other cell types or tissues.
DR GO; GO:0031683; F:G-protein beta/gamma-subunit complex binding; IEA:InterPro.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0007188; P:adenylate cyclase-modulating G protein-coupled receptor signaling pathway; IEA:InterPro.
DR CDD; cd00066; G-alpha; 1.
DR Gene3D; 1.10.400.10; GI Alpha 1, domain 2-like; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR001408; Gprotein_alpha_I.
DR InterPro; IPR001019; Gprotein_alpha_su.
DR InterPro; IPR011025; GproteinA_insert.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR10218; GTP-BINDING PROTEIN ALPHA SUBUNIT; 1.
DR PANTHER; PTHR10218:SF347; GUANINE NUCLEOTIDE-BINDING PROTEIN (G PROTEIN), ALPHA-INHIBITING ACTIVITY POLYPEPTIDE A; 1.
DR Pfam; PF00503; G-alpha; 1.
DR PRINTS; PR00318; GPROTEINA.
DR PRINTS; PR00441; GPROTEINAI.
DR SMART; SM00275; G_alpha; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF47895; Transducin (alpha subunit), insertion domain; 1.
DR PROSITE; PS51882; G_ALPHA; 1.
PE 4: Predicted;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000261580};
KW Transducer {ECO:0000256|ARBA:ARBA00023224}.
SQ SEQUENCE 354 AA; 40325 MW; 0DF3190DB99C2839 CRC64;
MGCTLSTDDK AAQERSKMID RNLRDDGEKA AREVKLLLLG AGESGKSTIV KQMKIIHEAG
YSEEECKQYK AVVYSNTIQS IIAIIRAMGR LKIDFADQAR ADDARQLFVL AGSAEEGFMT
SELAGVIQRL WKDGGVQACF SRSREYQLND SAAYYLNDLD RISNSAYVPT QQDVLRTRVK
TTGIVETHFT FKDLHFKMFD VGGQRSERKK WIHCFEGVTA IIFCVALSDY DLVLAEDEEM
NRMHESMKLF DSICNNKWFT ETSIILFLNK KDLFEEKIKK SPLTICFPEY AGANTYEEAA
AYVQCQFEDL NKRKDTKEIY THFTCATDTK NVQFVFDAVT DVIIKNNLKD CGLF
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