ID A0A3Q4GB14_NEOBR Unreviewed; 712 AA.
AC A0A3Q4GB14;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Cleavage and polyadenylation specificity factor subunit 3-like {ECO:0000313|Ensembl:ENSNBRP00000006110.1};
OS Neolamprologus brichardi (Fairy cichlid) (Lamprologus brichardi).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Lamprologini; Neolamprologus.
OX NCBI_TaxID=32507 {ECO:0000313|Ensembl:ENSNBRP00000006110.1, ECO:0000313|Proteomes:UP000261580};
RN [1] {ECO:0000313|Ensembl:ENSNBRP00000006110.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR AlphaFoldDB; A0A3Q4GB14; -.
DR STRING; 32507.ENSNBRP00000006110; -.
DR Ensembl; ENSNBRT00000006297.1; ENSNBRP00000006110.1; ENSNBRG00000004770.1.
DR GeneTree; ENSGT00940000155699; -.
DR OMA; CKQHITL; -.
DR Proteomes; UP000261580; Unplaced.
DR Bgee; ENSNBRG00000004770; Expressed in zone of skin and 8 other cell types or tissues.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR CDD; cd16292; CPSF3-like_MBL-fold; 1.
DR Gene3D; 3.40.50.10890; -; 1.
DR Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR InterPro; IPR022712; Beta_Casp.
DR InterPro; IPR021718; CPSF73-100_C.
DR InterPro; IPR001279; Metallo-B-lactamas.
DR InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR InterPro; IPR011108; RMMBL.
DR PANTHER; PTHR11203; CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR FAMILY MEMBER; 1.
DR PANTHER; PTHR11203:SF11; CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 3; 1.
DR Pfam; PF10996; Beta-Casp; 1.
DR Pfam; PF11718; CPSF73-100_C; 1.
DR Pfam; PF00753; Lactamase_B; 1.
DR Pfam; PF07521; RMMBL; 1.
DR SMART; SM01027; Beta-Casp; 1.
DR SMART; SM01098; CPSF73-100_C; 1.
DR SMART; SM00849; Lactamase_B; 1.
DR SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
PE 4: Predicted;
KW mRNA processing {ECO:0000256|ARBA:ARBA00022664};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000261580}.
FT DOMAIN 31..217
FT /note="Metallo-beta-lactamase"
FT /evidence="ECO:0000259|SMART:SM00849"
FT DOMAIN 253..400
FT /note="Beta-Casp"
FT /evidence="ECO:0000259|SMART:SM01027"
FT DOMAIN 510..711
FT /note="Pre-mRNA 3'-end-processing endonuclease
FT polyadenylation factor C-term"
FT /evidence="ECO:0000259|SMART:SM01098"
SQ SEQUENCE 712 AA; 80534 MW; A155E3D58AF1EB05 CRC64;
MTAKRKPDAT VPAEESDQLL IRPLGAGQEV GRSCIILEFK GRKIMLDCGI HPGLEGMDAL
PYIDLIDPAE IDLLLISHFH LDHCGALPWF LQKTSFKGRT FMTHATKAIY RWLLSDYVKV
SNISADDMLY TETDLEDSME KIETINFHEV KEVAGIKFWC YHAGHVLGAA MFMIEIAGVK
LLYTGDFSRQ EDRHLMAAEI PSVKPDILIT ESTYGTHIHE KREEREARFC NTVHDIVNRE
GRCLIPVFAL GRAQELLLIL DEYWQNHPEL HDIPIYYASS LARKCMAVYQ TYINAMNDKI
RKAININNPF VFKHISNLKV SECGPWVVSW LISLYMQYFY MCVFQSMDHF DDIGPSVVMA
SPGMMQSGLS RELFESWCTD RRNGVIIAGY CVEGTLAKHI MTEPDEITTM SGQKLPLKMS
VDYISFSAHT DYQQTSEFIR ALKPPHVILV HGEQNEMARL KAALIREYED NDEVHIEVHN
PRNTEAVTLN FRGEKLAKVM GSLADQKCIQ GQRVSGILVK RNFNYHILAP SDLSNYTDLS
MGMVTQTQAI PYTGPISLLV SQLRNLAGDV EQVEGTEKIT VRIFKSITMV HEASMVLLEW
VANPLNDMYA DAVATVILEV QSNPNAQKFV EGKKESFDMD VFVERLALML HDMFGDDCVN
FKDGKNLTVT VDGVTASVDP ETRLVSCAED ETLREMIEVA VHRLHDALSP AF
//
