ID A0A3Q4GCA1_NEOBR Unreviewed; 493 AA.
AC A0A3Q4GCA1;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=GTPase IMAP family member 8-like {ECO:0000313|Ensembl:ENSNBRP00000006640.1};
OS Neolamprologus brichardi (Fairy cichlid) (Lamprologus brichardi).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Lamprologini; Neolamprologus.
OX NCBI_TaxID=32507 {ECO:0000313|Ensembl:ENSNBRP00000006640.1, ECO:0000313|Proteomes:UP000261580};
RN [1] {ECO:0000313|Ensembl:ENSNBRP00000006640.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like
CC GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family.
CC IAN subfamily. {ECO:0000256|ARBA:ARBA00008535}.
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DR RefSeq; XP_006798070.1; XM_006798007.1.
DR RefSeq; XP_006798071.1; XM_006798008.1.
DR AlphaFoldDB; A0A3Q4GCA1; -.
DR Ensembl; ENSNBRT00000006836.1; ENSNBRP00000006640.1; ENSNBRG00000005236.1.
DR GeneTree; ENSGT00940000166816; -.
DR OMA; LPIQDEW; -.
DR OrthoDB; 4214137at2759; -.
DR Proteomes; UP000261580; Unplaced.
DR Bgee; ENSNBRG00000005236; Expressed in brain and 5 other cell types or tissues.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR006703; G_AIG1.
DR InterPro; IPR045058; GIMA/IAN/Toc.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR10903:SF139; GTPASE IMAP FAMILY MEMBER 4 ISOFORM X1; 1.
DR PANTHER; PTHR10903; GTPASE, IMAP FAMILY MEMBER-RELATED; 1.
DR Pfam; PF04548; AIG1; 3.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51720; G_AIG1; 2.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000261580}.
FT DOMAIN 18..241
FT /note="AIG1-type G"
FT /evidence="ECO:0000259|PROSITE:PS51720"
FT DOMAIN 271..471
FT /note="AIG1-type G"
FT /evidence="ECO:0000259|PROSITE:PS51720"
FT REGION 1..39
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 73..114
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 471..493
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 239..266
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 493 AA; 55040 MW; BFF217CE8B00EC06 CRC64;
MAAVSSASDT GDPRGRHPPE RRLLLLGGPR SGKTSTANSI LGDEVFDGAT ETTHSNVGHT
EIYGRRVTVV DTPPWAIPAN PGDDAEADNN DNAGAESDSP HRPPPSLDSE GPCMGAILCP
PGPHAILLVV SVTQPFAETE RRAAEEQLGA LGGGTWRYSM VLFTGIDKLP KGVFIEEHIA
NTGEALQWLV ERCGSRYHAF DNTRKETEEN TQVPELMEKV EEMITDNQGW YFEVNELILL
EEEQARRALE EERMRMEEHA RQREQMIGGP PRELRLLLLG WKGVGKSSVG NCILGRRYFE
SGQETELCLR RQALVSGRRV TIVDTPGWDW FSVRRTPKRI RQESQRGAAL LRPGPHTLLL
VLPVVSSLTA RKRRTLVAHI ETLFGDSACL HTMVLFSCGD WLGRTPIEEH ILRGGRELQR
LLEYSGNYYH VLDSKTPGKD RSVSVLLDKI EEMIRENGDK AFLPIQTEWL SEESSYSSDN
TEPEDDCRGC QLQ
//
