ID A0A3Q4GEA3_NEOBR Unreviewed; 116 AA.
AC A0A3Q4GEA3;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE RecName: Full=Potassium channel inwardly rectifying transmembrane domain-containing protein {ECO:0000259|Pfam:PF01007};
OS Neolamprologus brichardi (Fairy cichlid) (Lamprologus brichardi).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Lamprologini; Neolamprologus.
OX NCBI_TaxID=32507 {ECO:0000313|Ensembl:ENSNBRP00000006976.1, ECO:0000313|Proteomes:UP000261580};
RN [1] {ECO:0000313|Ensembl:ENSNBRP00000006976.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU003822}; Multi-
CC pass membrane protein {ECO:0000256|RuleBase:RU003822}.
CC -!- SIMILARITY: Belongs to the inward rectifier-type potassium channel (TC
CC 1.A.2.1) family. {ECO:0000256|RuleBase:RU003822}.
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DR AlphaFoldDB; A0A3Q4GEA3; -.
DR STRING; 32507.ENSNBRP00000006976; -.
DR Ensembl; ENSNBRT00000007175.1; ENSNBRP00000006976.1; ENSNBRG00000005463.1.
DR GeneTree; ENSGT00990000203615; -.
DR OMA; IRMANHR; -.
DR Proteomes; UP000261580; Unplaced.
DR Bgee; ENSNBRG00000005463; Expressed in brain and 1 other cell type or tissue.
DR GO; GO:0034702; C:monoatomic ion channel complex; IEA:UniProtKB-KW.
DR GO; GO:0005242; F:inward rectifier potassium channel activity; IEA:InterPro.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 2.60.40.1400; G protein-activated inward rectifier potassium channel 1; 1.
DR InterPro; IPR016449; K_chnl_inward-rec_Kir.
DR InterPro; IPR013518; K_chnl_inward-rec_Kir_cyto.
DR InterPro; IPR040445; Kir_TM.
DR PANTHER; PTHR11767; INWARD RECTIFIER POTASSIUM CHANNEL; 1.
DR PANTHER; PTHR11767:SF55; KIR6.3 PROTEIN; 1.
DR Pfam; PF01007; IRK; 1.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
PE 3: Inferred from homology;
KW Ion channel {ECO:0000256|RuleBase:RU003822};
KW Ion transport {ECO:0000256|RuleBase:RU003822};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Potassium {ECO:0000256|RuleBase:RU003822};
KW Potassium transport {ECO:0000256|RuleBase:RU003822};
KW Reference proteome {ECO:0000313|Proteomes:UP000261580};
KW Transmembrane {ECO:0000256|RuleBase:RU003822, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|RuleBase:RU003822};
KW Voltage-gated channel {ECO:0000256|RuleBase:RU003822}.
FT TRANSMEM 73..94
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 37..107
FT /note="Potassium channel inwardly rectifying transmembrane"
FT /evidence="ECO:0000259|Pfam:PF01007"
SQ SEQUENCE 116 AA; 13509 MW; 07AE1806888BDA22 CRC64;
MLARKGLLPD GFLLTRLAED QNQPNRSRSR SQRARFITKT GSCNVAHKNI REQGRFLQDV
FTTMVDLKWQ HSLLIFTSAF LCSWMLFAMI WWLLAFAHGD LEPRDPNGEL QLQQCK
//
