ID A0A3Q4GFR5_NEOBR Unreviewed; 352 AA.
AC A0A3Q4GFR5;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=Fork-head domain-containing protein {ECO:0000259|PROSITE:PS50039};
OS Neolamprologus brichardi (Fairy cichlid) (Lamprologus brichardi).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Lamprologini; Neolamprologus.
OX NCBI_TaxID=32507 {ECO:0000313|Ensembl:ENSNBRP00000001827.1, ECO:0000313|Proteomes:UP000261580};
RN [1] {ECO:0000313|Ensembl:ENSNBRP00000001827.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00089}.
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DR AlphaFoldDB; A0A3Q4GFR5; -.
DR STRING; 32507.ENSNBRP00000001827; -.
DR Ensembl; ENSNBRT00000001903.1; ENSNBRP00000001827.1; ENSNBRG00000001487.1.
DR GeneTree; ENSGT00940000157140; -.
DR OMA; ANLNICH; -.
DR Proteomes; UP000261580; Unplaced.
DR Bgee; ENSNBRG00000001487; Expressed in skeletal muscle tissue and 1 other cell type or tissue.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR CDD; cd20046; FH_FOXD1_D2-like; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR001766; Fork_head_dom.
DR InterPro; IPR018122; TF_fork_head_CS_1.
DR InterPro; IPR030456; TF_fork_head_CS_2.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11829; FORKHEAD BOX PROTEIN; 1.
DR PANTHER; PTHR11829:SF335; FORKHEAD BOX PROTEIN D2; 1.
DR Pfam; PF00250; Forkhead; 1.
DR PRINTS; PR00053; FORKHEAD.
DR SMART; SM00339; FH; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS00657; FORK_HEAD_1; 1.
DR PROSITE; PS00658; FORK_HEAD_2; 1.
DR PROSITE; PS50039; FORK_HEAD_3; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00089}; Nucleus {ECO:0000256|PROSITE-ProRule:PRU00089};
KW Reference proteome {ECO:0000313|Proteomes:UP000261580}.
FT DOMAIN 93..187
FT /note="Fork-head"
FT /evidence="ECO:0000259|PROSITE:PS50039"
FT DNA_BIND 93..187
FT /note="Fork-head"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00089"
FT REGION 45..81
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 45..78
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 352 AA; 38431 MW; 55C3FC928A0E43C2 CRC64;
MTLGTDMSDS SALSEDVDID VVGGDISVGK DGKYIHHDFN FDNDSDDNYS QNTAERVASP
GLSSSDCPSD QVGSNAETGT VIGDKPRKSA LVKPPYSYIA LITMAILQSP KKRLTLSEIC
EFISNRFPYY REKFPAWQNS IRHNLSLNDC FVKIPREPGN PGKGNYWTLD PDSADMFDNG
SFLRRRKRFK RHQNNDILRD SGGFLPGFGY APYGYNYGLQ LQNFHAAHNP YHPHHTGGSF
PFPNAPCTLP SSASIFPAPH HLPSLLGTDL RKPFYPQLSP SLPPLKTDSS APSRPSFSID
NIIGAANSTA SSYSAQPGSQ AQILAMLTPA LASASSHLNL SQEKCADSTR TP
//
