ID A0A3Q4GL43_NEOBR Unreviewed; 927 AA.
AC A0A3Q4GL43;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=E3 ubiquitin-protein ligase RNF31-like {ECO:0000313|Ensembl:ENSNBRP00000009691.1};
GN Name=RNF31 {ECO:0000313|Ensembl:ENSNBRP00000009691.1};
OS Neolamprologus brichardi (Fairy cichlid) (Lamprologus brichardi).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Lamprologini; Neolamprologus.
OX NCBI_TaxID=32507 {ECO:0000313|Ensembl:ENSNBRP00000009691.1, ECO:0000313|Proteomes:UP000261580};
RN [1] {ECO:0000313|Ensembl:ENSNBRP00000009691.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the RBR family. {ECO:0000256|ARBA:ARBA00008278}.
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DR AlphaFoldDB; A0A3Q4GL43; -.
DR STRING; 32507.ENSNBRP00000009691; -.
DR Ensembl; ENSNBRT00000009959.1; ENSNBRP00000009691.1; ENSNBRG00000007514.1.
DR GeneTree; ENSGT00530000064112; -.
DR OMA; GVCGVIE; -.
DR Proteomes; UP000261580; Unplaced.
DR Bgee; ENSNBRG00000007514; Expressed in brain and 2 other cell types or tissues.
DR GO; GO:0071797; C:LUBAC complex; IEA:InterPro.
DR GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd20337; BRcat_RBR_HOIP; 1.
DR CDD; cd16631; mRING-HC-C4C4_RBR_HOIP; 1.
DR CDD; cd20351; Rcat_RBR_HOIP; 1.
DR Gene3D; 1.20.58.2190; -; 1.
DR Gene3D; 6.10.140.1100; -; 1.
DR Gene3D; 1.10.8.10; DNA helicase RuvA subunit, C-terminal domain; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR047540; BRcat_RBR_RNF31-like.
DR InterPro; IPR002867; IBR_dom.
DR InterPro; IPR036339; PUB-like_dom_sf.
DR InterPro; IPR018997; PUB_domain.
DR InterPro; IPR047542; Rcat_RBR_RNF31-like.
DR InterPro; IPR026254; RNF31-like.
DR InterPro; IPR032065; RNF31-UBA.
DR InterPro; IPR041031; RNF31_C.
DR InterPro; IPR047541; RNF31_RBR_mRING-HC-like.
DR InterPro; IPR044066; TRIAD_supradom.
DR InterPro; IPR001876; Znf_RanBP2.
DR InterPro; IPR036443; Znf_RanBP2_sf.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR16004:SF4; E3 UBIQUITIN-PROTEIN LIGASE RNF31; 1.
DR PANTHER; PTHR16004; RING FINGER PROTEIN 31-RELATED; 1.
DR Pfam; PF18091; E3_UbLigase_RBR; 1.
DR Pfam; PF16678; HOIP-UBA; 1.
DR Pfam; PF01485; IBR; 1.
DR Pfam; PF09409; PUB; 1.
DR SMART; SM00647; IBR; 2.
DR SMART; SM00184; RING; 3.
DR SMART; SM00547; ZnF_RBZ; 2.
DR SUPFAM; SSF143503; PUG domain-like; 1.
DR SUPFAM; SSF90209; Ran binding protein zinc finger-like; 1.
DR SUPFAM; SSF57850; RING/U-box; 3.
DR PROSITE; PS51873; TRIAD; 1.
DR PROSITE; PS01358; ZF_RANBP2_1; 1.
DR PROSITE; PS50199; ZF_RANBP2_2; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000261580};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00322}.
FT DOMAIN 284..313
FT /note="RanBP2-type"
FT /evidence="ECO:0000259|PROSITE:PS50199"
FT DOMAIN 556..787
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS51873"
FT DOMAIN 560..608
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
SQ SEQUENCE 927 AA; 105657 MW; 59990204687CA21F CRC64;
MTKPPPCFTR GSYSLVYLYT QDVNQKFDIW IHHSRTNKAL YKYRTYFRLK LMLPLQTLGS
LQRLSTALNI LEKYGCNLTN PNRPKYWRTV KHNNPVFRAT VDAIQGGRAV LCLYGYSNQQ
PDGLSFPDDV TDPDVGRVAA VTLEVMSLRM ELEMLIKVCV NFLCACYYSV VSLLFCFTEN
CAICGIFRIS AHCLTCLQGL CSDCDRLYHS YPERANHHRT AVTSSTSSKN RSNESCTMVN
AASSILCEVC ERPRLATRPP VTPSHPPITP PRPPAPVLGM PGDPDSQWVC QFCTYLNYSP
AMVCEMCDLA RPEPAPLPEP APEDLDSWRQ NLIKEEGLKL IQLIRHGEKK GVSPEEVYTS
MRVAGDSNIL PCKWLKTELP LLLDQIRMLV ATSSLQSFSD KTPTEDKVSN LLAEAKLAWL
TAGGDTERAA RQALRDRLAK VKELCALGFS DESRCHEVLR QSGGEVRGAL ALLQRPLLEP
FHKRIWSEKP EPPVDIHHPD KQRVCRWLLA VYDLPSWGRC ELALSLLLEH SAPYSLEDVV
QAVQESHDRE FIKRVLAKEC PICLSVFPHS KMQSLTSCQC SVCCGCFQQH FTIAVRDKHI
RDMVCPVCWE PDINDPEHLN SYFSTLDIQL RECLEPEVYE LFHKKLTEQA LIKDPKFLWC
CHCSYGFIYD GDQLKVTCFQ CRNSFCAHCK KPWESQHAGL SCEQFQSWKR ENDPEYQRQG
LAGYLRDNGI TCPNCRFQYA LSKGGCMHFC CSQCRYQFCS GCNNPFHTTC AVDQCTVSGL
HAHHPRDCLF YLRDWEPSRL QALLQVNTHM FFYIFKWVPL FLLDLCGVIE QKDEGGQQSD
AACGAQTQPG HAGLCEKHYR EYLVSLINSH SIDPAPLYSS NELLLACRRY KVDDTHRDGE
DTFTYYTRLL EKLMDEVPLG DKVPRKK
//
