ID A0A3Q4GLQ7_NEOBR Unreviewed; 448 AA.
AC A0A3Q4GLQ7;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Keratin, type II cytoskeletal 8-like {ECO:0000313|Ensembl:ENSNBRP00000010480.1};
OS Neolamprologus brichardi (Fairy cichlid) (Lamprologus brichardi).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Lamprologini; Neolamprologus.
OX NCBI_TaxID=32507 {ECO:0000313|Ensembl:ENSNBRP00000010480.1, ECO:0000313|Proteomes:UP000261580};
RN [1] {ECO:0000313|Ensembl:ENSNBRP00000010480.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the intermediate filament family.
CC {ECO:0000256|RuleBase:RU000685}.
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DR AlphaFoldDB; A0A3Q4GLQ7; -.
DR Ensembl; ENSNBRT00000010773.1; ENSNBRP00000010480.1; ENSNBRG00000007993.1.
DR GeneTree; ENSGT00940000161090; -.
DR OMA; KYSNGYQ; -.
DR Proteomes; UP000261580; Unplaced.
DR Bgee; ENSNBRG00000007993; Expressed in brain.
DR GO; GO:0045095; C:keratin filament; IEA:InterPro.
DR Gene3D; 1.20.5.170; -; 1.
DR Gene3D; 1.20.5.500; Single helix bin; 1.
DR Gene3D; 1.20.5.1160; Vasodilator-stimulated phosphoprotein; 1.
DR InterPro; IPR018039; IF_conserved.
DR InterPro; IPR039008; IF_rod_dom.
DR InterPro; IPR003054; Keratin_II.
DR PANTHER; PTHR45616; GATA-TYPE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR45616:SF9; KERATIN, TYPE II CYTOSKELETAL 8-RELATED; 1.
DR Pfam; PF00038; Filament; 1.
DR PRINTS; PR01276; TYPE2KERATIN.
DR SMART; SM01391; Filament; 1.
DR SUPFAM; SSF64593; Intermediate filament protein, coiled coil region; 3.
DR PROSITE; PS00226; IF_ROD_1; 1.
DR PROSITE; PS51842; IF_ROD_2; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Intermediate filament {ECO:0000256|ARBA:ARBA00022754,
KW ECO:0000256|RuleBase:RU000685};
KW Reference proteome {ECO:0000313|Proteomes:UP000261580}.
FT DOMAIN 87..398
FT /note="IF rod"
FT /evidence="ECO:0000259|PROSITE:PS51842"
FT REGION 1..26
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 161..241
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 296..376
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1..25
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 448 AA; 50641 MW; 2AFB48325CCF1EF0 CRC64;
MSLSRTKRIS SSNSVRSSSG SRRLSGFGPV QGGFSGISLS SSSLYAGTNG HHHGLGAPLA
ALSVNKSLLA PLNLEIDPNL SMSRAHEKEQ IKSLNNRFAT FIDKVRYLEQ QNKMLETKLE
LLQGQGVSRS NVEPLFEAYM AGLRRQMDLV NNDKTKLDGE LRNMQGLVED YKHKYEDEIN
KRNNLENDFV ILKKDVDSAY LVKADLEDKV GALTDEINFL RNAYEEELRE LQASIKDTSV
VVQMDNSRSL NMEQIVAEVK SQYEEIAARS REEAEAWYKS KFDQMSVQAS QFGDELRIVK
GEIAELNRLI SRLQSEIEAV KAQRANLENQ LAEAEERGEL AVKEAKARIR DLEEALQRSK
QDMARQLREY QDLMNLKLAL DIEIATYRKL LEGEEDRLGQ QSILNIQPIS NYSNTKSTNG
YQSASSSPAP KLLIKTIETR DNSRYSIH
//
