ID A0A3Q4GRH6_NEOBR Unreviewed; 734 AA.
AC A0A3Q4GRH6;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE RecName: Full=Spermatid perinuclear RNA-binding protein {ECO:0000256|ARBA:ARBA00022368};
GN Name=STRBP {ECO:0000313|Ensembl:ENSNBRP00000011666.1};
OS Neolamprologus brichardi (Fairy cichlid) (Lamprologus brichardi).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Lamprologini; Neolamprologus.
OX NCBI_TaxID=32507 {ECO:0000313|Ensembl:ENSNBRP00000011666.1, ECO:0000313|Proteomes:UP000261580};
RN [1] {ECO:0000313|Ensembl:ENSNBRP00000011666.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR RefSeq; XP_006795605.1; XM_006795542.1.
DR AlphaFoldDB; A0A3Q4GRH6; -.
DR Ensembl; ENSNBRT00000011997.1; ENSNBRP00000011666.1; ENSNBRG00000009092.1.
DR GeneID; 102791526; -.
DR GeneTree; ENSGT00940000154687; -.
DR OMA; APLKGWX; -.
DR OrthoDB; 4565640at2759; -.
DR Proteomes; UP000261580; Unplaced.
DR Bgee; ENSNBRG00000009092; Expressed in muscle tissue and 5 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
DR CDD; cd19909; DSRM_STRBP_rpt1; 1.
DR CDD; cd19911; DSRM_STRBP_rpt2; 1.
DR Gene3D; 3.30.160.20; -; 2.
DR Gene3D; 3.30.460.10; Beta Polymerase, domain 2; 1.
DR InterPro; IPR014720; dsRBD_dom.
DR InterPro; IPR006561; DZF_dom.
DR InterPro; IPR049402; DZF_dom_C.
DR InterPro; IPR049401; DZF_dom_N.
DR InterPro; IPR043519; NT_sf.
DR InterPro; IPR044472; STRBP_DSRM_1.
DR PANTHER; PTHR45762:SF1; SPERMATID PERINUCLEAR RNA-BINDING PROTEIN; 1.
DR PANTHER; PTHR45762; ZINC FINGER RNA-BINDING PROTEIN; 1.
DR Pfam; PF00035; dsrm; 2.
DR Pfam; PF20965; DZF_C; 1.
DR Pfam; PF07528; DZF_N; 1.
DR SMART; SM00358; DSRM; 2.
DR SMART; SM00572; DZF; 1.
DR SUPFAM; SSF54768; dsRNA-binding domain-like; 2.
DR PROSITE; PS50137; DS_RBD; 2.
DR PROSITE; PS51703; DZF; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Developmental protein {ECO:0000256|ARBA:ARBA00022473};
KW Differentiation {ECO:0000256|ARBA:ARBA00022782};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000261580};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU00266}; Spermatogenesis {ECO:0000256|ARBA:ARBA00022871}.
FT DOMAIN 5..419
FT /note="DZF"
FT /evidence="ECO:0000259|PROSITE:PS51703"
FT DOMAIN 446..512
FT /note="DRBM"
FT /evidence="ECO:0000259|PROSITE:PS50137"
FT DOMAIN 567..633
FT /note="DRBM"
FT /evidence="ECO:0000259|PROSITE:PS50137"
FT REGION 57..89
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 181..236
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 515..556
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 65..83
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 185..224
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 521..535
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 536..556
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 734 AA; 80191 MW; 0EDBE9771C53444A CRC64;
MRSFRSFSND DRHVMAKHST IYPSSQELEA VQTLVSTVEC ALKHVSDWMD QSSCEVHNQF
DSQPADSTEE DDPGDEPSEE TEDSSDCYRE SSGGGLLCGV MRIGLVAKGL LIKGDMDLEL
VLMCRDKPTQ TLLDTVCHNL PTQIEKLTGE KYEVTSSLPE AAILVKTTTE PKLTLKITLT
SPAMREDDEE EEEEEELEEE EQELENGEEG EEVVEGEVEE EEEDPESKNG RVLGAAAQRV
EAEEEEEGEV LDRHRCLLAL AALRHAKWFQ ARVNGLKSCV IVLRILRDMC NRHPIWEPLK
GWPLELICEK AIATCNRPLG AGEALRRVME CLASGILLPG GPGLHDPCEK EPTNTLASMT
DQQAEDITFS AQHALRLMAF GQIYKVLEME PLPSNKPSQK YPWSDKEGLG LKRPYDDGAM
DDKDLIKKMK RNLRKVLDSK AIDSNQPMNA LMRLNQIRPG LQYRLLSQSG PVHAPVFTMS
VDLDGTVYEA SGSSKKTAKL HVAVKVLQAM GYPTGFDSDL DPMSSDEKSD SEGKSETSSH
TSNNPTHSSD SSNTLEVRTQ GPILTASGKN PVMELNEKRR GLKYELISES GGSHDKRFVM
EVEVDGQKFR GAGPNKKVAK ASAALAALEK LFSGPNAAAN KKKKLLPQTK GALAAAAAAS
AVAAQVARGR GRAALARGAF VSAAAPGYVT PGFGTPYGYS PAAAAAPAYG LPKRMLLLPV
MKVPAYPVPH YHFF
//
