ID A0A3Q4GRW4_NEOBR Unreviewed; 412 AA.
AC A0A3Q4GRW4;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Protein kinase C and casein kinase substrate in neurons protein 1-like {ECO:0000313|Ensembl:ENSNBRP00000011811.1};
OS Neolamprologus brichardi (Fairy cichlid) (Lamprologus brichardi).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Lamprologini; Neolamprologus.
OX NCBI_TaxID=32507 {ECO:0000313|Ensembl:ENSNBRP00000011811.1, ECO:0000313|Proteomes:UP000261580};
RN [1] {ECO:0000313|Ensembl:ENSNBRP00000011811.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004413};
CC Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004413};
CC Cytoplasmic side {ECO:0000256|ARBA:ARBA00004413}. Cell projection
CC {ECO:0000256|ARBA:ARBA00004316}. Cytoplasm
CC {ECO:0000256|ARBA:ARBA00004496}. Membrane
CC {ECO:0000256|ARBA:ARBA00004287}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004287}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004287}.
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DR Ensembl; ENSNBRT00000012143.1; ENSNBRP00000011811.1; ENSNBRG00000009125.1.
DR GeneTree; ENSGT00950000182973; -.
DR Proteomes; UP000261580; Unplaced.
DR Bgee; ENSNBRG00000009125; Expressed in testis and 1 other cell type or tissue.
DR GO; GO:0042995; C:cell projection; IEA:UniProtKB-SubCell.
DR GO; GO:0031410; C:cytoplasmic vesicle; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR CDD; cd11998; SH3_PACSIN1-2; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR031160; F_BAR.
DR InterPro; IPR001060; FCH_dom.
DR InterPro; IPR035743; PACSIN1/PACSIN2_SH3.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR23065; PROLINE-SERINE-THREONINE PHOSPHATASE INTERACTING PROTEIN 1; 1.
DR PANTHER; PTHR23065:SF11; SYNDAPIN, ISOFORM C; 1.
DR Pfam; PF00611; FCH; 1.
DR Pfam; PF00018; SH3_1; 1.
DR PRINTS; PR00452; SH3DOMAIN.
DR SMART; SM00055; FCH; 1.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS51741; F_BAR; 1.
DR PROSITE; PS50002; SH3; 1.
PE 4: Predicted;
KW Cell projection {ECO:0000256|ARBA:ARBA00023273};
KW Coiled coil {ECO:0000256|PROSITE-ProRule:PRU01077, ECO:0000256|SAM:Coils};
KW Cytoplasmic vesicle {ECO:0000256|ARBA:ARBA00023329};
KW Reference proteome {ECO:0000313|Proteomes:UP000261580};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 2..277
FT /note="F-BAR"
FT /evidence="ECO:0000259|PROSITE:PS51741"
FT DOMAIN 353..412
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 307..352
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 182..213
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 312..344
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 412 AA; 47626 MW; DD9F171414FD0268 CRC64;
XIQIYDIGIG IGHKKVGNYK RTVKRIDDGH RLCNDLMNCI QERAKIEKSY AQQLTEWSKR
WKQLVDKGPQ YGTVERAWMA MMTEAENVSE LHQDIKNYLI NEDFEKVKNW QKDSYHKQMM
GGFKETKEAE EGFKKAQKPW AKKLKELEAA KKTYHMTCKE EKLATTREAN IKGESSVAAD
QQKKLHEKVD KCKQDSQKAK EKYEKALDEL SKCTPSYMEN MEQVFDQCQQ FEEKRLSFLR
EVLLDVKRHL NLTENQSYAT VYRELERTIT SEYNPDLVHN ISKKEKSKKG NDVVMLTHVT
TAGDHAVDRG SVSSYDKNQP YTASTEWSDE DQTAPNSGND TNGGMNPFDE DMGTGVRVRA
LYDYDGQEQD ELSFRVGDEL TKLEDEDDQG WCKGRLDNGK LGLYPANYVE TI
//
