ID A0A3Q4GT88_NEOBR Unreviewed; 1293 AA.
AC A0A3Q4GT88;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Contactin associated protein like 3 {ECO:0000313|Ensembl:ENSNBRP00000013080.1};
OS Neolamprologus brichardi (Fairy cichlid) (Lamprologus brichardi).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Lamprologini; Neolamprologus.
OX NCBI_TaxID=32507 {ECO:0000313|Ensembl:ENSNBRP00000013080.1, ECO:0000313|Proteomes:UP000261580};
RN [1] {ECO:0000313|Ensembl:ENSNBRP00000013080.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the neurexin family.
CC {ECO:0000256|ARBA:ARBA00010241}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR STRING; 32507.ENSNBRP00000013080; -.
DR Ensembl; ENSNBRT00000013449.1; ENSNBRP00000013080.1; ENSNBRG00000009721.1.
DR GeneTree; ENSGT00940000160228; -.
DR Proteomes; UP000261580; Unplaced.
DR Bgee; ENSNBRG00000009721; Expressed in brain.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0048856; P:anatomical structure development; IEA:UniProt.
DR GO; GO:0032101; P:regulation of response to external stimulus; IEA:UniProt.
DR CDD; cd00054; EGF_CA; 2.
DR CDD; cd00057; FA58C; 1.
DR CDD; cd00110; LamG; 4.
DR Gene3D; 2.60.120.1000; -; 1.
DR Gene3D; 2.60.120.200; -; 4.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 2.10.25.10; Laminin; 2.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR000421; FA58C.
DR InterPro; IPR036056; Fibrinogen-like_C.
DR InterPro; IPR002181; Fibrinogen_a/b/g_C_dom.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR001791; Laminin_G.
DR PANTHER; PTHR15036:SF40; CONTACTIN-ASSOCIATED PROTEIN-LIKE 4; 1.
DR PANTHER; PTHR15036; PIKACHURIN-LIKE PROTEIN; 1.
DR Pfam; PF00008; EGF; 1.
DR Pfam; PF00754; F5_F8_type_C; 1.
DR Pfam; PF02210; Laminin_G_2; 4.
DR SMART; SM00181; EGF; 2.
DR SMART; SM00231; FA58C; 1.
DR SMART; SM00282; LamG; 4.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 4.
DR SUPFAM; SSF57196; EGF/Laminin; 1.
DR SUPFAM; SSF56496; Fibrinogen C-terminal domain-like; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR PROSITE; PS50026; EGF_3; 2.
DR PROSITE; PS01285; FA58C_1; 1.
DR PROSITE; PS50022; FA58C_3; 1.
DR PROSITE; PS51406; FIBRINOGEN_C_2; 1.
DR PROSITE; PS50025; LAM_G_DOMAIN; 4.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00122}; EGF-like domain {ECO:0000256|PROSITE-ProRule:PRU00076};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000261580};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 1225..1250
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 33..179
FT /note="F5/8 type C"
FT /evidence="ECO:0000259|PROSITE:PS50022"
FT DOMAIN 185..357
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 363..530
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 532..569
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 568..620
FT /note="Fibrinogen C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51406"
FT DOMAIN 779..944
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 945..983
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 1005..1193
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT REGION 1267..1293
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1274..1293
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 917..944
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00122"
SQ SEQUENCE 1293 AA; 143152 MW; E02C06FADCCD3C04 CRC64;
NFISYLCIIL DTQSHKQYTL YLSFILISNL EVCHSPLVSN LPPSSFRSSS QLSGSHGPGF
AKLNRREGAG GWSPLSSDRY QWLEVDLGGR TRITAVATQG RYGSSDWQTA YLLMFSDTGH
NWKQYRQEDS IGAFAGNSNA DSVVQHKLQH QVIARYVRLI PLNWNPNGRI GLRLETYGCP
YNSDVLSFNG RSSLIYRLTP RPRQMSSESI SLKFKTLKNS GILLHAEGQN GHSLTLELEK
GKLQLLIRKG TTLNRYLVTL GSLLDDQHWH HVAVEHHSNH LKLTVDKSTE HKSRSCRHFI
VSACLCTLSP VQMILGAQQG FSYTSFYGCL ENPVYNGLHL VDLAKQKDQR GNVTFSCSEP
VFVAMTFTGP QSFLRLPRID QSSLGISVGL QFRTWNKAGL LLTFELPNRE GRVWLYLSKA
RTHLQIHKSA LNDGQWHSVD LISGGGRLTI TVDGDEGASA HASPSFLITT GGHIFFGGCP
AEENSQECLN PFKAFHGCMR LLTVDNRPLD LIKVQQRLIG NYSHLQIDMC GIIDRCSPSH
CEHGGSCSQS WSTFHCNCTG TGYSGATCHS SIYEQSCEAY KHKGNISGYY YIDVDSSGPI
KPQLLYCNMT EDNTWMVIHH NNTDLTRVQP SPEVNTYEVH FEYASDEEQL AAIISLSEHC
EQEIAYHCRK SRLLTSSEGS PLSWWVGGPG VGQMHTHWGG APPGSQQCAC SLQNNCVDSR
YHCNCDADSN EWTNDSGLLT HKETLPVRSL VLGDIQRPGS ESTYKVGPLR CHGDKNVWNA
AFFDKETSYL HFPTLHGELS ADISFLFKTT SSSGVFLENL GIKDFIRIEL NSSNEVLFSF
DVGNGPLEVS VKAGSPLNDN RWHRIQAERN VKEASLRLDE LPAVTQEAPA DGHIHLQLNS
QLFIGGTASR QKGFRGCIRS LQLNGVTLDL EERAKITPGV QAGCPGHCSS YGSLCQNQGR
CVERPTSFSC DCSSSAYTGP FCNKEVSASF KSETSVTYVF KEQMVNELNR SSSGSSSFPS
SIYSDITLKA ENVSLSFRTS QSPALLLYVS SYHREYFAVL LSKPDKLEVR YRLDSSKDAE
ILRSKVKNLA DRQLHVITIS RLADVVSMQI DQNPKEDFNL TSGVEFNGIR SLVLGRVHDS
EGLDPDLAQI ASLGFTGCLS AVLFNSISPL KAALLHPKTS PVTVTGPLIQ SICGFTSANL
SHATETTHHL SGKRPLVNAI RSDSALIGGV IAVAIFVTVS ALAVMARFLY RRKCTCQRQE
VKTVKPEDNP ELPFRSRITS QNGPTENQKE YFI
//
