ID A0A3Q4GUH6_NEOBR Unreviewed; 223 AA.
AC A0A3Q4GUH6;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=Fibroblast growth factor {ECO:0000256|RuleBase:RU049442};
DE Short=FGF {ECO:0000256|RuleBase:RU049442};
OS Neolamprologus brichardi (Fairy cichlid) (Lamprologus brichardi).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Lamprologini; Neolamprologus.
OX NCBI_TaxID=32507 {ECO:0000313|Ensembl:ENSNBRP00000007292.1, ECO:0000313|Proteomes:UP000261580};
RN [1] {ECO:0000313|Ensembl:ENSNBRP00000007292.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the heparin-binding growth factors family.
CC {ECO:0000256|ARBA:ARBA00007936, ECO:0000256|RuleBase:RU049442}.
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DR RefSeq; XP_006801288.1; XM_006801225.1.
DR AlphaFoldDB; A0A3Q4GUH6; -.
DR Ensembl; ENSNBRT00000007497.1; ENSNBRP00000007292.1; ENSNBRG00000005695.1.
DR GeneID; 102791340; -.
DR GeneTree; ENSGT00940000155929; -.
DR OMA; SECKFRE; -.
DR OrthoDB; 3945519at2759; -.
DR Proteomes; UP000261580; Unplaced.
DR Bgee; ENSNBRG00000005695; Expressed in skeletal muscle tissue and 2 other cell types or tissues.
DR GO; GO:0008083; F:growth factor activity; IEA:InterPro.
DR CDD; cd00058; FGF; 1.
DR Gene3D; 2.80.10.50; -; 1.
DR InterPro; IPR002209; Fibroblast_GF_fam.
DR InterPro; IPR008996; IL1/FGF.
DR PANTHER; PTHR11486; FIBROBLAST GROWTH FACTOR; 1.
DR PANTHER; PTHR11486:SF156; FIBROBLAST GROWTH FACTOR; 1.
DR Pfam; PF00167; FGF; 1.
DR PRINTS; PR00263; HBGFFGF.
DR PRINTS; PR00262; IL1HBGF.
DR SMART; SM00442; FGF; 1.
DR SUPFAM; SSF50353; Cytokine; 1.
DR PROSITE; PS00247; HBGF_FGF; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000261580}.
FT REGION 16..36
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 189..223
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 16..30
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 201..223
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 223 AA; 25567 MW; ECD42494310E20A2 CRC64;
MTRYYSLFRR LLSRESKGEE ADEEEGSVHK NSSQQEPQLK GIVTRLFSEQ GFFLQMQPDG
AISGTKDENS DYTLFNLIPV GLRVVAIQGV KAALYVAMNA EGFLYTSDVF TPECKFKESV
FENYYVIYSS TMYRQHESGR AWFLGLNKEG VIMKGNRVKK TKPCSHFVPR PIEVCMYKEP
SLHELEEKLL KSSRSPTMNS EERARSLERE QRAAESSTER EAS
//
