ID A0A3Q4GWI3_NEOBR Unreviewed; 1191 AA.
AC A0A3Q4GWI3;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Liprin-alpha-2-like {ECO:0000313|Ensembl:ENSNBRP00000013571.1};
OS Neolamprologus brichardi (Fairy cichlid) (Lamprologus brichardi).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Lamprologini; Neolamprologus.
OX NCBI_TaxID=32507 {ECO:0000313|Ensembl:ENSNBRP00000013571.1, ECO:0000313|Proteomes:UP000261580};
RN [1] {ECO:0000313|Ensembl:ENSNBRP00000013571.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the liprin family. Liprin-alpha subfamily.
CC {ECO:0000256|ARBA:ARBA00007026}.
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DR AlphaFoldDB; A0A3Q4GWI3; -.
DR STRING; 32507.ENSNBRP00000013571; -.
DR Ensembl; ENSNBRT00000013945.1; ENSNBRP00000013571.1; ENSNBRG00000010460.1.
DR GeneTree; ENSGT01050000244900; -.
DR OMA; DHEWIGN; -.
DR Proteomes; UP000261580; Unplaced.
DR Bgee; ENSNBRG00000010460; Expressed in brain and 1 other cell type or tissue.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR CDD; cd09562; SAM_liprin-alpha1_2_3_4_repeat1; 1.
DR CDD; cd09565; SAM_liprin-alpha1_2_3_4_repeat2; 1.
DR CDD; cd09568; SAM_liprin-alpha1_2_3_4_repeat3; 1.
DR Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 3.
DR InterPro; IPR029515; Liprin.
DR InterPro; IPR037620; Liprin-alpha_SAM_rpt_1.
DR InterPro; IPR037621; Liprin-alpha_SAM_rpt_2.
DR InterPro; IPR037622; Liprin-alpha_SAM_rpt_3.
DR InterPro; IPR001660; SAM.
DR InterPro; IPR013761; SAM/pointed_sf.
DR PANTHER; PTHR12587; LAR INTERACTING PROTEIN LIP -RELATED PROTEIN; 1.
DR PANTHER; PTHR12587:SF6; LIPRIN-ALPHA-2; 1.
DR Pfam; PF00536; SAM_1; 2.
DR Pfam; PF07647; SAM_2; 1.
DR SMART; SM00454; SAM; 3.
DR SUPFAM; SSF47769; SAM/Pointed domain; 3.
DR PROSITE; PS50105; SAM_DOMAIN; 3.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000261580}.
FT DOMAIN 870..936
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
FT DOMAIN 962..1019
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
FT DOMAIN 1043..1112
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
FT REGION 1..29
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 684..719
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 741..764
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 99..140
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 191..225
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 264..326
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 357..436
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 487..517
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 630..671
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 10..29
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 685..705
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1191 AA; 135688 MW; 6187C4060B272A64 CRC64;
MMCEVMPTIS EDTALSQRGS QSSASDPDSH FEQLMVNMLD ERDRLLDTLR ETQESLGLAQ
QHLQDVIYDR DSLQRQLSSA LPQVSSLNPS LLKGSFYEFA ALTKELNACR EQLLEKEEEI
SELKAERNNT RLLLEHLECL VSRHERSLRM TVVKRQAQSP SGVSSEVEVL KALKSLFEHH
KALDEKVRER LRVSLERVSA LEEELTAANQ EIVALREQNA HIQRKVASGE GGEDILEGSE
AQQKVHGKRL SNGSLEPAHE ASQVIELQDL LEKQNYELAQ MKERMSSLSS RVSEVEQELE
TARKDLIKSE EMNNKYQRDI KEVTAQKLIL KLIQTSHLFP VSFNDKFEFH LSDSKYQLNM
EEKNRQLQER LELAEQKLQQ TMRKAETLPE VEAELAQRIA ALTKAEERHG SIEERMRHLE
CQLEEKNQEL LRARQREKMN EEHNKRLSDT VDRLLTESNE RLQLHLKERM AALEEKNMLI
QDSETYRKQY EESIQEKSQL AEDIEKLRSE LDQFRLRAGS LTEPTLSRSH LDTSAELRFS
LGSLAETQSD HYRSAKVIHR QRRGRIGLRE TKAKSLGEPE WRSQQLGVMG GHHFESDTEM
SDIDDDDRET LFSSMDLLSP SGHSDAQTLA MMLQEQLDAI NKEIRLIQEE KESTELRAEE
IENRVASVSL EGLNLARMHH HGASITASAT ASSLASSSPP SGHSTPKLDP RSPARDMERM
GVMTLPSDLR KHRRKIAAVD EDGREDKATI KCETSPPPTP RTVRMTHTLP ASSHNDARGI
VASLEAEASA LSSVASSQDS LHKQPKKKGI KSSIGRLFGK KEKGRLAHLA HRQDMGVSKL
GTQAEKDRRL KKKHELLEEA RRKGLPFAQW DGPTVVAWLE LWLGMPAWYV AACRANVKSG
AIMSALSDTE IQREIGISNP LHRLKLRLAI QEMVSLTSPS APPTSRTTLA YGDMNHEWIG
NEWLPSLGLP QYRSYFMECL VDARMLDHLT KKDLRVHLKM VDSFHRTSLQ YGIMCLKKLN
YDRKELERRR EQSQHEMRDV LVWSNERVIR WVQSIGLRDY ANILLESGVH GALVALDDNF
DYSSLALLLQ IPTQNTQARQ ILEREYNNLL ALGTDRRLDE CDDKDFRGPS WRRQFPPRDI
HGISMMPGSA ETLPAGFRLT ATSGHSRRLP PEVGPSAVQR LDSSTVRTYS C
//
