ID   A0A3Q4GYE3_NEOBR        Unreviewed;       196 AA.
AC   A0A3Q4GYE3;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=Si:dkey-57c15.1 {ECO:0000313|Ensembl:ENSNBRP00000008857.1};
OS   Neolamprologus brichardi (Fairy cichlid) (Lamprologus brichardi).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Lamprologini; Neolamprologus.
OX   NCBI_TaxID=32507 {ECO:0000313|Ensembl:ENSNBRP00000008857.1, ECO:0000313|Proteomes:UP000261580};
RN   [1] {ECO:0000313|Ensembl:ENSNBRP00000008857.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the amiloride-sensitive sodium channel (TC
CC       1.A.6) family. {ECO:0000256|RuleBase:RU000679}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   AlphaFoldDB; A0A3Q4GYE3; -.
DR   STRING; 32507.ENSNBRP00000008857; -.
DR   Ensembl; ENSNBRT00000009114.1; ENSNBRP00000008857.1; ENSNBRG00000006936.1.
DR   GeneTree; ENSGT00940000165535; -.
DR   OMA; AGHEMRD; -.
DR   Proteomes; UP000261580; Unplaced.
DR   Bgee; ENSNBRG00000006936; Expressed in brain.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005272; F:sodium channel activity; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.3590.10; acid-sensing ion channel 1 domain; 1.
DR   Gene3D; 1.10.287.770; YojJ-like; 1.
DR   InterPro; IPR001873; ENaC.
DR   PANTHER; PTHR11690:SF170; ACID-SENSING ION CHANNEL 1; 1.
DR   PANTHER; PTHR11690; AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED; 1.
DR   Pfam; PF00858; ASC; 1.
DR   PRINTS; PR01078; AMINACHANNEL.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Ion channel {ECO:0000256|RuleBase:RU000679};
KW   Ion transport {ECO:0000256|RuleBase:RU000679};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000261580};
KW   Sodium {ECO:0000256|ARBA:ARBA00023053};
KW   Sodium channel {ECO:0000256|ARBA:ARBA00022461,
KW   ECO:0000256|RuleBase:RU000679};
KW   Sodium transport {ECO:0000256|ARBA:ARBA00023201,
KW   ECO:0000256|RuleBase:RU000679};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU000679};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|RuleBase:RU000679}.
FT   TRANSMEM        45..68
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        80..98
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   196 AA;  22994 MW;  007C51097081115D CRC64;
     MDLKADSEDM DYRRPAPIEV FAARSTLHGI SHMFTYKRMY IKRTLWILFF LASVGVLVMV
     CVDRVQFYFE YPHVTKLDEV AASLIIFPSV TFCNLNSFRF SRVTRNDLYH AGEFLALLNG
     RCIRDPHLVE ENVLQILKER ADFDSYKPRP FNMREFYDRT GHDIKDMLLS CSYRGEECAA
     EDFKVVSCAR KQLNVF
//