ID A0A3Q4GZ61_NEOBR Unreviewed; 575 AA.
AC A0A3Q4GZ61;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE SubName: Full=Eomesodermin-like {ECO:0000313|Ensembl:ENSNBRP00000014551.1};
OS Neolamprologus brichardi (Fairy cichlid) (Lamprologus brichardi).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Lamprologini; Neolamprologus.
OX NCBI_TaxID=32507 {ECO:0000313|Ensembl:ENSNBRP00000014551.1, ECO:0000313|Proteomes:UP000261580};
RN [1] {ECO:0000313|Ensembl:ENSNBRP00000014551.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00201}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00201}.
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DR AlphaFoldDB; A0A3Q4GZ61; -.
DR Ensembl; ENSNBRT00000014943.1; ENSNBRP00000014551.1; ENSNBRG00000011108.1.
DR GeneTree; ENSGT00940000158728; -.
DR Proteomes; UP000261580; Unplaced.
DR Bgee; ENSNBRG00000011108; Expressed in brain.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0009790; P:embryo development; IEA:UniProt.
DR GO; GO:0045893; P:positive regulation of DNA-templated transcription; IEA:InterPro.
DR Gene3D; 2.60.40.820; Transcription factor, T-box; 1.
DR InterPro; IPR008967; p53-like_TF_DNA-bd_sf.
DR InterPro; IPR032385; T-box_assoc.
DR InterPro; IPR046360; T-box_DNA-bd.
DR InterPro; IPR036960; T-box_sf.
DR InterPro; IPR001699; TF_T-box.
DR InterPro; IPR018186; TF_T-box_CS.
DR PANTHER; PTHR11267:SF13; EOMESODERMIN HOMOLOG; 1.
DR PANTHER; PTHR11267; T-BOX PROTEIN-RELATED; 1.
DR Pfam; PF00907; T-box; 1.
DR Pfam; PF16176; T-box_assoc; 1.
DR PRINTS; PR00937; TBOX.
DR SMART; SM00425; TBOX; 1.
DR SUPFAM; SSF49417; p53-like transcription factors; 1.
DR PROSITE; PS01283; TBOX_1; 1.
DR PROSITE; PS01264; TBOX_2; 1.
DR PROSITE; PS50252; TBOX_3; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00201};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00201}; Reference proteome {ECO:0000313|Proteomes:UP000261580};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 154..339
FT /note="T-box"
FT /evidence="ECO:0000259|PROSITE:PS50252"
FT REGION 1..37
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 14..28
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 575 AA; 63412 MW; DB2BCBBA1C31B260 CRC64;
MLGSEGESSS YSSSKDTADE RRKSPAVEGD DPVVSNRYTE HGMSADRYYI PSAISKQSPE
AASHCSFIPY TPSGAVYTPS SAGRYPSSLH LGSVLQPAGF PPSAPGRSHI GPTYQLGQSP
GCIYPPYTSS GSALGNMALP PATTGPGVRS QVYLCNRPLW LKFHRHQTEM IITKQGRRMF
PFLSFNIAGL SVTAHYNVFV EVVLADPNHW RFQGGKWVTC GKADNSSQGN KIYIHPESPN
TGAHWMRQEI SFSKLKLTNN KGTSHNTSQM IVLQSLHKYQ PRLHIVEVTE DGVEDLNSDL
KTQCFTFPET QFIAVTAYQN TDITQLKIDH NPFAKGFRDN YDSMYTAPEN DRLTPSPTDS
PRAHQIVPGT RYAMQPLFQD QFVNSLPQNR FYNSERAVPQ TNSLLSPQSE DAASQRWFVT
SVQQGGSSSG TTNKLDLTPY EGEYSSSLLP YGIKSLPMPT SHALSYYPDS PFTAMSAGWG
SRAAYQRKVT SSLPWSPRPS PTASFAEDSE KVKAQMEEEV NGSGALISSW TEPQPSALSL
DKTNSYSLAC KRRRVSLNGP STEESSTYYP FYTNP
//
