ID A0A3Q4H0X6_NEOBR Unreviewed; 880 AA.
AC A0A3Q4H0X6;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Calcium-independent phospholipase A2-gamma-like {ECO:0000313|Ensembl:ENSNBRP00000015231.1};
OS Neolamprologus brichardi (Fairy cichlid) (Lamprologus brichardi).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Lamprologini; Neolamprologus.
OX NCBI_TaxID=32507 {ECO:0000313|Ensembl:ENSNBRP00000015231.1, ECO:0000313|Proteomes:UP000261580};
RN [1] {ECO:0000313|Ensembl:ENSNBRP00000015231.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR RefSeq; XP_006794269.1; XM_006794206.1.
DR AlphaFoldDB; A0A3Q4H0X6; -.
DR STRING; 32507.ENSNBRP00000015231; -.
DR Ensembl; ENSNBRT00000015646.1; ENSNBRP00000015231.1; ENSNBRG00000011811.1.
DR GeneID; 102784448; -.
DR GeneTree; ENSGT00940000154738; -.
DR OMA; HINIYFK; -.
DR OrthoDB; 5477952at2759; -.
DR Proteomes; UP000261580; Unplaced.
DR Bgee; ENSNBRG00000011811; Expressed in muscle tissue and 4 other cell types or tissues.
DR GO; GO:0004620; F:phospholipase activity; IEA:InterPro.
DR GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-UniRule.
DR CDD; cd07211; Pat_PNPLA8; 1.
DR Gene3D; 3.40.1090.10; Cytosolic phospholipase A2 catalytic domain; 1.
DR InterPro; IPR016035; Acyl_Trfase/lysoPLipase.
DR InterPro; IPR045217; PNPLA8-like.
DR InterPro; IPR002641; PNPLA_dom.
DR PANTHER; PTHR24185; CALCIUM-INDEPENDENT PHOSPHOLIPASE A2-GAMMA; 1.
DR PANTHER; PTHR24185:SF1; CALCIUM-INDEPENDENT PHOSPHOLIPASE A2-GAMMA; 1.
DR Pfam; PF01734; Patatin; 1.
DR SUPFAM; SSF52151; FabD/lysophospholipase-like; 1.
DR PROSITE; PS51635; PNPLA; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Lipid degradation {ECO:0000256|ARBA:ARBA00022963};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW Reference proteome {ECO:0000313|Proteomes:UP000261580}.
FT DOMAIN 547..742
FT /note="PNPLA"
FT /evidence="ECO:0000259|PROSITE:PS51635"
FT REGION 254..291
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 340..365
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 255..270
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 880 AA; 99492 MW; 3752CD5F9CB7787A CRC64;
MGRYLSTKLC SCCVNRTLKL YSKYKYTMNL LRKDHGLTKA PLCLDLHRYL QLSPPQPSRF
ATKATFKKVK HSDTSSTFYS LLRDLTEKAR HPQAVRFYSS SNKDVFKAKA PVGIFDEAQN
NSLLSSVGGC LGQSFNQLSR HINIYFKRKE VLSLSENASV VMSTPEYACR SQRISQSQQA
ATEENIPESK DTTQTLKCKD KQWDSVTSHS TQETSGLQLF HISSLTTRFG EGYNYVAHHI
NTFFSQGLAK VQKRENLEPP SKETNRREKR RKIQIRGKQS KVKAALEPNS NSSTWEEGYL
HFARHINKYF GAKVTDEAQN TKEQPLVEKD WTYKKHLLTQ STSQTHSASS QLKQEESITP
GAAGSFHSSC NTTKISENYY QTSQHINQYF KGQSGLNEDT ESQKSPKRLK SVSFMDYLCN
PTSTIPELLG VYRKSNSKTA IPAPQAVLNK KLVLNRKQAD EMTCVFTDSL RLASTPEALT
DCVEALNEHL IHYPSCKALI WKEKIAVSML RQRKNYEHNQ ELQAALRETL ALIGYADPVK
GRGIRVLSID GGGTRGVVPL QILKLLEDQT GKKIHQLFDY ICGVSTGAVL AFMLGLAHFS
IEECADMYRR FGSEVFRQNP LVGTVKMGWS HSYYNTETWE TILREKLGDR VLIKTARDFF
SPKVSAVSTV VNWGTSPKAF VFRNYNHKPG SLSRYAGGSG YQMWQAVRAS SAAPGYFQEF
TLENDIHQDG GITLNNPCAV AVHESHLLWP NQDFQCVLSL GTGRYDSAKK GPATSTSLRA
KISNLICSAT DTEGVHTLLD DLLAPDVYFR FNPMLSSDVS LDENRPQALD QLQRDTQNYL
ERNQPKLARL CLVLSAERSV IRRTKDWFSE RAWEMKQRLM
//
