ID A0A3Q4H4D5_NEOBR Unreviewed; 130 AA.
AC A0A3Q4H4D5;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=Astrocytic phosphoprotein PEA-15 {ECO:0000256|ARBA:ARBA00015367};
DE AltName: Full=15 kDa phosphoprotein enriched in astrocytes {ECO:0000256|ARBA:ARBA00033278};
GN Name=PEA15 {ECO:0000313|Ensembl:ENSNBRP00000014793.1};
OS Neolamprologus brichardi (Fairy cichlid) (Lamprologus brichardi).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Lamprologini; Neolamprologus.
OX NCBI_TaxID=32507 {ECO:0000313|Ensembl:ENSNBRP00000014793.1, ECO:0000313|Proteomes:UP000261580};
RN [1] {ECO:0000313|Ensembl:ENSNBRP00000014793.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_006808770.1; XM_006808707.1.
DR AlphaFoldDB; A0A3Q4H4D5; -.
DR STRING; 32507.ENSNBRP00000014793; -.
DR Ensembl; ENSNBRT00000015198.1; ENSNBRP00000014793.1; ENSNBRG00000011459.1.
DR GeneID; 102796735; -.
DR GeneTree; ENSGT00390000000230; -.
DR OMA; IACSRDW; -.
DR OrthoDB; 5384276at2759; -.
DR Proteomes; UP000261580; Unplaced.
DR Bgee; ENSNBRG00000011459; Expressed in brain and 5 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0008643; P:carbohydrate transport; IEA:UniProtKB-KW.
DR GO; GO:0000165; P:MAPK cascade; IEA:InterPro.
DR GO; GO:0042981; P:regulation of apoptotic process; IEA:InterPro.
DR CDD; cd08338; DED_PEA15; 1.
DR Gene3D; 1.10.533.10; Death Domain, Fas; 1.
DR InterPro; IPR011029; DEATH-like_dom_sf.
DR InterPro; IPR001875; DED_dom.
DR InterPro; IPR029546; PEA15_DED.
DR PANTHER; PTHR48169:SF1; ASTROCYTIC PHOSPHOPROTEIN PEA-15; 1.
DR PANTHER; PTHR48169; DED DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF01335; DED; 1.
DR SMART; SM00031; DED; 1.
DR SUPFAM; SSF47986; DEATH domain; 1.
DR PROSITE; PS50168; DED; 1.
PE 4: Predicted;
KW Apoptosis {ECO:0000256|ARBA:ARBA00022703};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000261580};
KW Sugar transport {ECO:0000256|ARBA:ARBA00022597};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 3..81
FT /note="DED"
FT /evidence="ECO:0000259|PROSITE:PS50168"
SQ SEQUENCE 130 AA; 15118 MW; 2CB11D0A087092E0 CRC64;
MAEYSSLLSD LSENITNEDL EQLKSACKED IPEDQSNNIT SSKEWFSYLE KNDKLAQDNL
SYIEHIFEIS RRPDLLTRVI EYRTKVLKIS EDDEIDTKLT RIPSAKKYKD IIRQPSEDEI
IKLAPPPKKA
//
