ID A0A3Q4H4Z5_NEOBR Unreviewed; 533 AA.
AC A0A3Q4H4Z5;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE SubName: Full=Transmembrane anterior posterior transformation protein 1 homolog {ECO:0000313|Ensembl:ENSNBRP00000017760.1};
GN Name=TAPT1 {ECO:0000313|Ensembl:ENSNBRP00000017760.1};
OS Neolamprologus brichardi (Fairy cichlid) (Lamprologus brichardi).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Lamprologini; Neolamprologus.
OX NCBI_TaxID=32507 {ECO:0000313|Ensembl:ENSNBRP00000017760.1, ECO:0000313|Proteomes:UP000261580};
RN [1] {ECO:0000313|Ensembl:ENSNBRP00000017760.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the TAPT1 family.
CC {ECO:0000256|ARBA:ARBA00008803}.
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DR AlphaFoldDB; A0A3Q4H4Z5; -.
DR STRING; 32507.ENSNBRP00000017760; -.
DR Ensembl; ENSNBRT00000018238.1; ENSNBRP00000017760.1; ENSNBRG00000013674.1.
DR GeneTree; ENSGT00390000010628; -.
DR OMA; QPTHQKE; -.
DR Proteomes; UP000261580; Unplaced.
DR Bgee; ENSNBRG00000013674; Expressed in testis and 6 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0051216; P:cartilage development; IEA:UniProtKB-KW.
DR GO; GO:0001503; P:ossification; IEA:UniProtKB-KW.
DR InterPro; IPR008010; Tatp1.
DR PANTHER; PTHR13317:SF4; TRANSMEMBRANE ANTERIOR POSTERIOR TRANSFORMATION PROTEIN 1 HOMOLOG; 1.
DR PANTHER; PTHR13317; UNCHARACTERIZED; 1.
DR Pfam; PF05346; DUF747; 1.
PE 3: Inferred from homology;
KW Chondrogenesis {ECO:0000256|ARBA:ARBA00023188};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Osteogenesis {ECO:0000256|ARBA:ARBA00022855};
KW Reference proteome {ECO:0000313|Proteomes:UP000261580};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 108..125
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 164..185
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 235..255
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 401..418
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 424..449
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 466..516
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 533 AA; 61192 MW; D17D6A715B727DE9 CRC64;
MADQSGTELS EEKEAEIELK KRQKITWEGL HKSGKIGITP DLPETLGFYD ISAVRREQRE
LSADPSLTRF ISTELTRGYF LEHNEAKYTE RRERVYTCMR IPKELEKLMI FGFFLCVDAF
LYVFTLLPLR VLLALLRLFT LPCCGFSGSR LLQPAQVCDM LRGLILVLCF SMMHYVDYSM
MYHLIRGQSV IKLYIIYNML EVADRLFSSF GQDILDALYW TATEPKERKR DNIGVIPHFF
MAVFYVFLHA ILIMVQASTL NVAFNSHNKS LLTIMMSNNF VEIKGSVFKK FEKNNLFQMS
NSDIKERFTS YVLLLIVCLR NMEQFSWNPD HLWVLFPDVF MVVTSEVAVD VIKHAFITKF
NDITADVYSE YRASLAFDLV SSRQKNACTD YSDSVARRMG FIPLPLAVLL IRVVMSSVRL
QGALSYTCVL LFYLGLVTLK VLNSIVLLGK SCVYVKRAKM EDKLFERPST APSSSAKSPS
KADPARCRTP SDDEDEEEEE EEAAQLPSET KHKTSKKDLL EIDRFTICGN RID
//
