ID A0A3Q4H523_NEOBR Unreviewed; 1270 AA.
AC A0A3Q4H523;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Period circadian protein homolog 2-like {ECO:0000313|Ensembl:ENSNBRP00000016801.1};
OS Neolamprologus brichardi (Fairy cichlid) (Lamprologus brichardi).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Lamprologini; Neolamprologus.
OX NCBI_TaxID=32507 {ECO:0000313|Ensembl:ENSNBRP00000016801.1, ECO:0000313|Proteomes:UP000261580};
RN [1] {ECO:0000313|Ensembl:ENSNBRP00000016801.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR AlphaFoldDB; A0A3Q4H523; -.
DR STRING; 32507.ENSNBRP00000016801; -.
DR Ensembl; ENSNBRT00000017252.1; ENSNBRP00000016801.1; ENSNBRG00000012934.1.
DR GeneTree; ENSGT00940000160817; -.
DR OMA; EYQCVAG; -.
DR Proteomes; UP000261580; Unplaced.
DR Bgee; ENSNBRG00000012934; Expressed in blood and 9 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013655; PAS_fold_3.
DR InterPro; IPR048814; Per1-3_PAS-A.
DR InterPro; IPR022728; Period_circadian-like_C.
DR PANTHER; PTHR11269; PERIOD CIRCADIAN PROTEIN; 1.
DR PANTHER; PTHR11269:SF13; PERIOD CIRCADIAN PROTEIN HOMOLOG 3; 1.
DR Pfam; PF08447; PAS_3; 1.
DR Pfam; PF21353; Per3-like_PAS-A; 1.
DR Pfam; PF12114; Period_C; 1.
DR SMART; SM00091; PAS; 2.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50112; PAS; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Reference proteome {ECO:0000313|Proteomes:UP000261580}.
FT DOMAIN 336..382
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT REGION 1..103
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 595..644
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 681..713
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 764..867
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 969..1070
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1084..1160
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1239..1270
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 65..90
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 598..635
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 814..838
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 850..867
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 970..992
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1010..1044
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1045..1062
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1084..1132
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1133..1154
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1239..1259
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1270 AA; 138225 MW; EBD516892049AFC7 CRC64;
MPGGDSRLHG EEPALPSATA NGGEVEQELS GKQNGRETSK HLGGEESGVS GGEVGQEDEE
MASGSHDLCS STNHSPGSAS GSTSVSAKSS EHAEAGKGQD HREVMNAVAE MKKRLPSDKR
SRSKASTVEA LHYALNCVKQ VQANSEYYKL LMQNGQDERR NATVCTLEEL ERVTSEHTLK
NTDSFVVVFS LASGRVLYAS EQAPSILCCK RKFLESAKFV ELLFHQDVNV FYSHTAQPHL
PPWSNSHTAG VLFDCAQVKS FFCRIRGGKD REGEMRYNPF RITPYQLKVQ GSGSSGEEEE
PCCLALAERI ISGYEAPRIP MDKRIFTTTH SPGCVFLEVD DRAVPLLGYL PQDLIGTSLL
TCIHPEDRPL MLAMHRKVLK HAGQPPFEHS PVRLRCQNGD YITLDTSWSS FINPWSRKVA
FIIGRHKVRT SPLNEDVFAA KAKEFVPVTH EEIKDLQAKI YKLFLQPVHN NGSSGYGSLG
SNGSHEHYIS IASSSDSNGN VWEDSHREPM TLQQICADVN RVKSWGQQAY LDSNHKIAFL
GKRVTAPLPP AASNAEVREH KASRKQTHIP SYQQINCVDN IIRYLESCTG PALKRKSESH
SLVTSSSSSS TSEDDKPAGA TDTAQESSDV VVETEVSVSP PTPAVVGAPL TDITMSTKAM
SVVSVTSQCS YSSTIVHVPQ PESEATALED APMGSEPADP APTPVRRAPS PAAEERRFVG
LTKEVLSAHT QKEEQEYVDR FRHRILQSPY SSYLQLDNSS LAHSHHPGDY LRPLSAGGWN
RSRKGKPRHK RPKPQGSSDS YASPPEPARC VPDSSWPSSE SSQPQVGAPY SQTSPVQVPF
FPVMGKPAPE QSPRTQQLPG AAPTGLQPPD QLSYNFNIMQ PTQSLPGMQQ IQMETIQNVQ
NTQNFHNLQP IAPTQTFNPS FMAPVMAVIL PNYPTFTPGY PSIYPQSAQS ILPQIPITMT
GYAPVSAPFP QPQFQAQPGP HSQTSPGLLL CSPRASSSVG EEEEAAGPTA LFSSSRSSSP
LQLNLLQEEL PKPSEGQSST GHNHAESLHE QHANERDVAG ESGNHDAQST SSELLDLLLQ
EDARSGTGSN ASGSGSGESG GSLGSGSGSN GTSTSHTGSS NSSKYFASND SSDTSRKARK
SQETLAEHKH TFENQSENSL WSMIQHTPER VMMTYQIHTR DQNKVLAEDR EKLRVLQPLQ
PWFSQEQREE LAEVHPWIKQ HAIPQEIDTQ GCVSCSSGAG MSHPTHPAAP DSSSLLESPQ
HDPIGLVVDT
//
