ID A0A3Q4H5P3_NEOBR Unreviewed; 815 AA.
AC A0A3Q4H5P3;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Probable G-protein coupled receptor 133-like {ECO:0000313|Ensembl:ENSNBRP00000011762.1};
GN Name=ADGRD1 {ECO:0000313|Ensembl:ENSNBRP00000011762.1};
OS Neolamprologus brichardi (Fairy cichlid) (Lamprologus brichardi).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Lamprologini; Neolamprologus.
OX NCBI_TaxID=32507 {ECO:0000313|Ensembl:ENSNBRP00000011762.1, ECO:0000313|Proteomes:UP000261580};
RN [1] {ECO:0000313|Ensembl:ENSNBRP00000011762.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR AlphaFoldDB; A0A3Q4H5P3; -.
DR STRING; 32507.ENSNBRP00000011762; -.
DR Ensembl; ENSNBRT00000012094.1; ENSNBRP00000011762.1; ENSNBRG00000009078.1.
DR GeneTree; ENSGT00940000159783; -.
DR OMA; PANTVMP; -.
DR Proteomes; UP000261580; Unplaced.
DR Bgee; ENSNBRG00000009078; Expressed in mesonephros and 5 other cell types or tissues.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:InterPro.
DR GO; GO:0009653; P:anatomical structure morphogenesis; IEA:UniProt.
DR GO; GO:0007166; P:cell surface receptor signaling pathway; IEA:InterPro.
DR GO; GO:0048731; P:system development; IEA:UniProt.
DR Gene3D; 2.60.120.200; -; 1.
DR Gene3D; 2.60.220.50; -; 1.
DR Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 1.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR046338; GAIN_dom_sf.
DR InterPro; IPR017981; GPCR_2-like_7TM.
DR InterPro; IPR000832; GPCR_2_secretin-like.
DR InterPro; IPR017983; GPCR_2_secretin-like_CS.
DR InterPro; IPR000203; GPS.
DR PANTHER; PTHR12011; ADHESION G-PROTEIN COUPLED RECEPTOR; 1.
DR PANTHER; PTHR12011:SF216; ADHESION G-PROTEIN COUPLED RECEPTOR D1; 1.
DR Pfam; PF00002; 7tm_2; 1.
DR Pfam; PF01825; GPS; 1.
DR Pfam; PF13385; Laminin_G_3; 1.
DR PRINTS; PR00249; GPCRSECRETIN.
DR SMART; SM00303; GPS; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF81321; Family A G protein-coupled receptor-like; 1.
DR PROSITE; PS00650; G_PROTEIN_RECEP_F2_2; 1.
DR PROSITE; PS50261; G_PROTEIN_RECEP_F2_4; 1.
DR PROSITE; PS50221; GPS; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000261580};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 510..533
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 545..563
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 575..593
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 614..633
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 653..679
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 700..721
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 727..750
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 507..751
FT /note="G-protein coupled receptors family 2 profile 2"
FT /evidence="ECO:0000259|PROSITE:PS50261"
SQ SEQUENCE 815 AA; 90747 MW; DF67EB9CFA6F8E83 CRC64;
MAFCLRIRIF TAFVSFIKVN LRKVLDTASH YWPLDAVEGI HELWDHNGNR SDIVEGMVNK
GIFLNGDNGG TFLHFGNYQN TCISDPNLCG PEGITFSFFW KNHESASRFA VASGGKVISN
GFSVYTNPLG GYVEFYTRSN KHRWRANIDV PGPYWTHILF TWTKKDGLKV YINATLTAEN
KNGSISEETY GDPYPDLVIG TANNKGYSHY VTGAFDEFVI WERALSPENI SLYYNATIGR
TSADMSPPVI SSLQEELRPT DFLPVQSFLK TLPNGTISRD TANNLTQQQS TPVVSGLVKT
VDRVMEHVVT NLEDSPNSLI SLDGTSFVAD YSLMKLPQNF ELSHYRFPTE GKSYISVPGE
AFAMESQTTI VGLFYHNMHS YYKEISPVKT RINEAADYKD HKIHVASCLI SLKVEPLPAL
SVNLSGAPLI KIVLTHVLTK EQQDQVQNQS NKVFLYCAFL DYSSKEGVWS NKGCVRAHGN
MTYSVCLCNH LTNFAILMQV VPLKVALSTI GYVGCSISIF CLAITLVTFA VLSSVSTIRN
QRYHIHANLS FAILVAEILL LISARFDPGT LPCKVMAVLL HFFFLSAFAW MLVEGLHLYS
MVIKVFGSED SKHFYYYGIG WGSPFLICVV SMTSALDSYG KVDNCWLSLQ NGAIWAFVAP
ALFVIVVNIG ILISVTRIIS RISGENYKVH GDANAVKLTI KAVAVLLPIL GISWIFGVLV
VNTQSLPFLY IFAVFNSLQG FFVFLFHCLL NSEVRAAFKH KTKVWSLTSS SIRNINVKPF
NSDIMNGHKE GVTPTKMNTW DKSTNSANRI DLSAV
//
