ID   A0A3Q4H614_NEOBR        Unreviewed;       399 AA.
AC   A0A3Q4H614;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   SubName: Full=Acyl-coenzyme A thioesterase 1-like {ECO:0000313|Ensembl:ENSNBRP00000017186.1};
OS   Neolamprologus brichardi (Fairy cichlid) (Lamprologus brichardi).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Lamprologini; Neolamprologus.
OX   NCBI_TaxID=32507 {ECO:0000313|Ensembl:ENSNBRP00000017186.1, ECO:0000313|Proteomes:UP000261580};
RN   [1] {ECO:0000313|Ensembl:ENSNBRP00000017186.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the C/M/P thioester hydrolase family.
CC       {ECO:0000256|ARBA:ARBA00006538}.
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DR   AlphaFoldDB; A0A3Q4H614; -.
DR   STRING; 32507.ENSNBRP00000017186; -.
DR   Ensembl; ENSNBRT00000017650.1; ENSNBRP00000017186.1; ENSNBRG00000013263.1.
DR   GeneTree; ENSGT01010000222336; -.
DR   OMA; HDWEAYG; -.
DR   Proteomes; UP000261580; Unplaced.
DR   Bgee; ENSNBRG00000013263; Expressed in zone of skin and 2 other cell types or tissues.
DR   GO; GO:0016790; F:thiolester hydrolase activity; IEA:InterPro.
DR   GO; GO:0006637; P:acyl-CoA metabolic process; IEA:InterPro.
DR   Gene3D; 2.60.40.2240; Acyl-CoA thioester hydrolase/BAAT N-terminal domain; 1.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR016662; Acyl-CoA_thioEstase_long-chain.
DR   InterPro; IPR014940; BAAT_C.
DR   InterPro; IPR006862; Thio_Ohase/aa_AcTrfase.
DR   InterPro; IPR042490; Thio_Ohase/BAAT_N.
DR   PANTHER; PTHR10824:SF36; ACYL-COA THIOESTERASE 19-RELATED; 1.
DR   PANTHER; PTHR10824; ACYL-COENZYME A THIOESTERASE-RELATED; 1.
DR   Pfam; PF08840; BAAT_C; 2.
DR   Pfam; PF04775; Bile_Hydr_Trans; 1.
DR   PIRSF; PIRSF016521; Acyl-CoA_hydro; 2.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000261580}.
FT   DOMAIN          19..148
FT                   /note="Acyl-CoA thioester hydrolase/bile acid-CoA amino
FT                   acid N-acetyltransferase"
FT                   /evidence="ECO:0000259|Pfam:PF04775"
FT   DOMAIN          208..250
FT                   /note="BAAT/Acyl-CoA thioester hydrolase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF08840"
FT   DOMAIN          285..390
FT                   /note="BAAT/Acyl-CoA thioester hydrolase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF08840"
FT   ACT_SITE        236
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR016521-1"
FT   ACT_SITE        300
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR016521-1"
FT   ACT_SITE        335
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR016521-1"
SQ   SEQUENCE   399 AA;  44016 MW;  9673B3697EF224E2 CRC64;
     MTQVVPPILS VTPSRALVDE KFKVLVENLP PGCPVTVRSL HQSEDKHDWE AYGHYISDHS
     GVVSVSEDLS YGGTYTGKEP MGLLWSMRPV PGSRPGLRLR KMNVCTPMLV TISVHSGHEG
     FRDKAPLASV LTERWYMAPG IQRISINEQG VQGTLFIPPG PGPFPGLLDM WGGGGGLLEY
     RAALLASHGY VSLALDYLGF DQESENLELK YFETAFNIIK DHPQVMPDRV GIFGLSLGSL
     VAVTLAAYST ITKVGPCLSA RVNEDNQVIW KDVGLEFITD PSNIVGRINC PTLLVNGCDD
     QNWPTVETAE DVARLMREAG KEHLLSRLAY PDTGHLIEPP FSPHFRATTF VIRSSKEKVI
     LLWGGQTKPH SDAQEDSWRK ILSFLQFHLY CGPSLKAKI
//