ID A0A3Q4H6F8_NEOBR Unreviewed; 244 AA.
AC A0A3Q4H6F8;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Heat shock transcription factor 2 {ECO:0000313|Ensembl:ENSNBRP00000018290.1};
OS Neolamprologus brichardi (Fairy cichlid) (Lamprologus brichardi).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Lamprologini; Neolamprologus.
OX NCBI_TaxID=32507 {ECO:0000313|Ensembl:ENSNBRP00000018290.1, ECO:0000313|Proteomes:UP000261580};
RN [1] {ECO:0000313|Ensembl:ENSNBRP00000018290.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the HSF family. {ECO:0000256|ARBA:ARBA00006403,
CC ECO:0000256|RuleBase:RU004020}.
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DR AlphaFoldDB; A0A3Q4H6F8; -.
DR Ensembl; ENSNBRT00000018780.1; ENSNBRP00000018290.1; ENSNBRG00000014096.1.
DR GeneTree; ENSGT00940000155906; -.
DR Proteomes; UP000261580; Unplaced.
DR Bgee; ENSNBRG00000014096; Expressed in mesonephros and 8 other cell types or tissues.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR000232; HSF_DNA-bd.
DR InterPro; IPR027725; HSF_fam.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR10015:SF206; HEAT SHOCK FACTOR PROTEIN; 1.
DR PANTHER; PTHR10015; HEAT SHOCK TRANSCRIPTION FACTOR; 1.
DR Pfam; PF00447; HSF_DNA-bind; 1.
DR PRINTS; PR00056; HSFDOMAIN.
DR SMART; SM00415; HSF; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS00434; HSF_DOMAIN; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000261580}.
FT DOMAIN 49..73
FT /note="HSF-type DNA-binding"
FT /evidence="ECO:0000259|PROSITE:PS00434"
SQ SEQUENCE 244 AA; 28724 MW; EF90DFD56CB5D1FB CRC64;
MKHNSNVPAF LTKLWTLVED TDTNEFICWS QEGNSFLVLD EQRFAKEILP KFFKHNNMAS
FIRQLNMYGF RKVMHIDTGI VKQERDGPVE FQHPYFRQGQ DDLLENIKRK VSNARPEDNK
IRQEDLTKIL ASVQSVHSKQ ENIDARLATL KRSSGRTYMK RHNQMTGIVY RNISVFQRTT
ISWFLFLFLN RPILMNGNGK KPKFIHQIYD DKVCVEQVSK EWLLFTLCFS KVLFLSAALN
KLEV
//
