ID A0A3Q4H785_NEOBR Unreviewed; 257 AA.
AC A0A3Q4H785;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=DLA class II histocompatibility antigen, DR-1 beta chain-like {ECO:0000313|Ensembl:ENSNBRP00000015888.1};
OS Neolamprologus brichardi (Fairy cichlid) (Lamprologus brichardi).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Lamprologini; Neolamprologus.
OX NCBI_TaxID=32507 {ECO:0000313|Ensembl:ENSNBRP00000015888.1, ECO:0000313|Proteomes:UP000261580};
RN [1] {ECO:0000313|Ensembl:ENSNBRP00000015888.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3Q4H785; -.
DR Ensembl; ENSNBRT00000016318.1; ENSNBRP00000015888.1; ENSNBRG00000011261.1.
DR GeneTree; ENSGT00950000183127; -.
DR Proteomes; UP000261580; Unplaced.
DR Bgee; ENSNBRG00000011261; Expressed in mesonephros and 5 other cell types or tissues.
DR GO; GO:0042613; C:MHC class II protein complex; IEA:InterPro.
DR GO; GO:0019882; P:antigen processing and presentation; IEA:InterPro.
DR GO; GO:0006955; P:immune response; IEA:InterPro.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003597; Ig_C1-set.
DR InterPro; IPR011162; MHC_I/II-like_Ag-recog.
DR InterPro; IPR014745; MHC_II_a/b_N.
DR InterPro; IPR000353; MHC_II_b_N.
DR PANTHER; PTHR19944:SF106; DLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DR-1 BETA CHAIN-LIKE-RELATED; 1.
DR PANTHER; PTHR19944; MHC CLASS II-RELATED; 1.
DR Pfam; PF07654; C1-set; 1.
DR Pfam; PF00969; MHC_II_beta; 1.
DR SMART; SM00407; IGc1; 1.
DR SMART; SM00921; MHC_II_beta; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 1.
DR SUPFAM; SSF54452; MHC antigen-recognition domain; 1.
DR PROSITE; PS50835; IG_LIKE; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000261580};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..257
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5018744815"
FT TRANSMEM 207..228
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 111..193
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT COILED 67..94
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 257 AA; 29572 MW; 8D8001F832A15E70 CRC64;
FTMHIRCTLL LTSMFLLFSR ADAYFGYGLI RCLFTSEDDV VYLVQLYFNK VLQAQYNSTL
GKYVGYTEKM KEIANELNKN QRFLEQEKKN KQKCRTNVPL VFDVLSRPVE PTVKLRLAES
PESEHPGTLM CSAYNFYPKQ IKLTWLRDGK EATSNVTSTD ELPNGNWLYQ SHSYLEIIPK
PGENISCMVE HASLMEPKFY DWEKNKIAIG VAGLLLGLVF VLGGAVFYKR NTTSEKNDKR
HLLNVSICNL SIYISKF
//
