ID A0A3Q4HCQ5_NEOBR Unreviewed; 705 AA.
AC A0A3Q4HCQ5;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE SubName: Full=FCH and double SH3 domains protein 2-like {ECO:0000313|Ensembl:ENSNBRP00000018053.1};
GN Name=FCHSD2 {ECO:0000313|Ensembl:ENSNBRP00000018053.1};
OS Neolamprologus brichardi (Fairy cichlid) (Lamprologus brichardi).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Lamprologini; Neolamprologus.
OX NCBI_TaxID=32507 {ECO:0000313|Ensembl:ENSNBRP00000018053.1, ECO:0000313|Proteomes:UP000261580};
RN [1] {ECO:0000313|Ensembl:ENSNBRP00000018053.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3Q4HCQ5; -.
DR STRING; 32507.ENSNBRP00000018053; -.
DR Ensembl; ENSNBRT00000018543.1; ENSNBRP00000018053.1; ENSNBRG00000013902.1.
DR GeneTree; ENSGT00510000046732; -.
DR OMA; TPMMEEP; -.
DR Proteomes; UP000261580; Unplaced.
DR Bgee; ENSNBRG00000013902; Expressed in zone of skin and 4 other cell types or tissues.
DR CDD; cd11894; SH3_FCHSD2_2; 1.
DR CDD; cd11761; SH3_FCHSD_1; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 2.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR031160; F_BAR.
DR InterPro; IPR035556; FCHSD2_SH3_2.
DR InterPro; IPR035460; FCHSD_SH3_1.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR15735:SF11; F-BAR AND DOUBLE SH3 DOMAINS PROTEIN 2; 1.
DR PANTHER; PTHR15735; FCH AND DOUBLE SH3 DOMAINS PROTEIN; 1.
DR Pfam; PF00018; SH3_1; 1.
DR Pfam; PF14604; SH3_9; 1.
DR PRINTS; PR00452; SH3DOMAIN.
DR SMART; SM00326; SH3; 2.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR SUPFAM; SSF50044; SH3-domain; 2.
DR PROSITE; PS51741; F_BAR; 1.
DR PROSITE; PS50002; SH3; 2.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|PROSITE-ProRule:PRU01077, ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000261580};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 45..271
FT /note="F-BAR"
FT /evidence="ECO:0000259|PROSITE:PS51741"
FT DOMAIN 454..515
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 552..614
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 615..705
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 353..380
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 619..634
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 635..667
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 687..705
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 705 AA; 80038 MW; 5F019E4E8FEF01E3 CRC64;
MSFCFIQVKV TQELKNTHTE QMTRLHFKHQ TECDLLEDMR YEHALQKLAS QYLKRDWPGI
NPDDQRTDYR NVYAVWRSYL EGTVQVSQSR LNVCDNYKSQ VSEPAKTVRL YKEQQLKKTI
DQLSGIQAEL QESVKELAKA KKKYYDCEQV AHAIREKADI EAKSKLGLFQ SRISLQKASV
KLKAKRSDCN SKATQARNDY LLTLAAANAH HDRYYHTDLL HCIQALDGRI YEHVKDYLVA
LCRTELEASQ ATHNTYQFLL DKSTRIMQEY NQQLFMQENP VFHKAHDFQF QPSECDTSRQ
LESESGTTEE HSLNKEARKW ATRVAREHKN IIHYKRSLEE CESHGLPPTE QGRLDLEMKI
EDTKENMRKA ETIKLKAEAR LDLLRQVGVA VDTWLKSAMN QVCIVSECWE SFHCGSVCVL
KGTVDLEREE GEECEENMEV FDDSSSSPSG TLRNYPLTCK VLYSYKASQP DELTIDEQEM
LEVIEDGDME DWVKARNKAG QVGYVPEKYL QFPTSNSLLS MLQSLATLDA RSHTSSNSTE
PELHSGCING DTNMMYVRAL YDYEGQADEE LSFSEGAVIR LLSRDTQTDD GFWEGELNGR
VGVFPSVLVE DLTENGETSA GGAGDTQISP SLKLPSSLPP LPLYDQPPIS PFTSPETSTP
PPLPRSPSAA LNGEHKLPLP ASSHKGPLSA HSKTTNTTRT MFNEK
//
