ID   A0A3Q4HHP6_NEOBR        Unreviewed;       709 AA.
AC   A0A3Q4HHP6;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=Pre-rRNA processing protein FTSJ3-like {ECO:0000313|Ensembl:ENSNBRP00000022895.1};
OS   Neolamprologus brichardi (Fairy cichlid) (Lamprologus brichardi).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Lamprologini; Neolamprologus.
OX   NCBI_TaxID=32507 {ECO:0000313|Ensembl:ENSNBRP00000022895.1, ECO:0000313|Proteomes:UP000261580};
RN   [1] {ECO:0000313|Ensembl:ENSNBRP00000022895.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A3Q4HHP6; -.
DR   Ensembl; ENSNBRT00000023493.1; ENSNBRP00000022895.1; ENSNBRG00000017453.1.
DR   GeneTree; ENSGT00550000075004; -.
DR   OMA; DITTEDC; -.
DR   Proteomes; UP000261580; Unplaced.
DR   Bgee; ENSNBRG00000017453; Expressed in zone of skin and 7 other cell types or tissues.
DR   GO; GO:0005634; C:nucleus; IEA:InterPro.
DR   GO; GO:0008173; F:RNA methyltransferase activity; IEA:UniProt.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   GO; GO:0006364; P:rRNA processing; IEA:InterPro.
DR   Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 2.
DR   InterPro; IPR002877; RNA_MeTrfase_FtsJ_dom.
DR   InterPro; IPR012920; rRNA_MeTfrase_SPB1-like_C.
DR   InterPro; IPR024576; rRNA_MeTfrase_Spb1_DUF3381.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   PANTHER; PTHR10920:SF13; PRE-RRNA 2'-O-RIBOSE RNA METHYLTRANSFERASE FTSJ3; 1.
DR   PANTHER; PTHR10920; RIBOSOMAL RNA METHYLTRANSFERASE; 1.
DR   Pfam; PF11861; DUF3381; 1.
DR   Pfam; PF01728; FtsJ; 1.
DR   Pfam; PF07780; Spb1_C; 1.
DR   SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW   Reference proteome {ECO:0000313|Proteomes:UP000261580};
KW   S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT   DOMAIN          91..160
FT                   /note="Ribosomal RNA methyltransferase FtsJ"
FT                   /evidence="ECO:0000259|Pfam:PF01728"
FT   DOMAIN          193..355
FT                   /note="DUF3381"
FT                   /evidence="ECO:0000259|Pfam:PF11861"
FT   DOMAIN          469..686
FT                   /note="Ribosomal RNA methyltransferase SPB1-like C-
FT                   terminal"
FT                   /evidence="ECO:0000259|Pfam:PF07780"
FT   REGION          289..323
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          386..498
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          674..709
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          588..625
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        289..305
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        306..320
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        403..437
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        674..688
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   709 AA;  80711 MW;  7A3CE91B56253EAA CRC64;
     MGKKLKVGKT RKDKFYHLAK ETYRSRSSFK LIQLNRKFQF LQKARALVDL CAAPGLQVAS
     KFMPVSSLII VDLVPIKPIP NVVTLQEDIT TEKCRQAHLT LMALKLACEF LTKGGTFVTK
     VFRSKDYQPL LWIFQQFFKK VQATKPQASR NESAEIFVIF VAPDKIDSKF FDPKYAFKEV
     EVQAKTVKEL IPVKKPKAEG YTDGDLTLYH SFTVTDFLKA ENPVDFLGKA SEITFNNPDL
     EFHSATSNEI KECCRDIKVL GRKELLLLNW RSKLRRYLAK KLKDEAKQLD QEISDEEGSN
     SEEEAGKKED EEEEGEDNEE EEMVKKLAEL KAEEVAELKR KKRKLLKEQR KQRERVELKM
     DLPGVSIAST EDSSLFSLVS IKKKKVKFTN QEEEEDEEQD GGLVVELEGK DEKMERQADL
     WFSKGKGKKR KAEEDIKEEE EQQEAALPEE EKAGPSLEAA EESDSDSDDS SDDEEITRMK
     QARGAGGVSG EVDDDGDFQV VPVESTKKAR ILSPEGLALG TQIATSKKRA RDLVDSSFHF
     ATSDEPWEVP EWFLDDERKH RKRPVPVTKE MVEEYKEKWK EINARPIKRV AEAKARKKRR
     TLKKMEQAKK KAEAVVNTVD ISEREKMAQL KIYKKAGLGK EKREVTYVVS KKGAGKKVRR
     PPGVKGVFKV VDGRMKKDLR GMQRKEQRAK GGKGKHGKGR QAKGGKGGV
//