ID A0A3Q4HMT1_NEOBR Unreviewed; 376 AA.
AC A0A3Q4HMT1;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=Septin {ECO:0000256|PIRNR:PIRNR006698};
OS Neolamprologus brichardi (Fairy cichlid) (Lamprologus brichardi).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Lamprologini; Neolamprologus.
OX NCBI_TaxID=32507 {ECO:0000313|Ensembl:ENSNBRP00000024895.1, ECO:0000313|Proteomes:UP000261580};
RN [1] {ECO:0000313|Ensembl:ENSNBRP00000024895.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC {ECO:0000256|ARBA:ARBA00004245}.
CC -!- SIMILARITY: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like
CC GTPase superfamily. Septin GTPase family.
CC {ECO:0000256|PIRNR:PIRNR006698, ECO:0000256|RuleBase:RU004560}.
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DR RefSeq; XP_006790000.1; XM_006789937.1.
DR AlphaFoldDB; A0A3Q4HMT1; -.
DR Ensembl; ENSNBRT00000025547.1; ENSNBRP00000024895.1; ENSNBRG00000018717.1.
DR GeneID; 102779164; -.
DR CTD; 335925; -.
DR GeneTree; ENSGT00940000159913; -.
DR OrthoDB; 5396944at2759; -.
DR Proteomes; UP000261580; Unplaced.
DR Bgee; ENSNBRG00000018717; Expressed in zone of skin and 3 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-UniRule.
DR CDD; cd01850; CDC_Septin; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR030379; G_SEPTIN_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR016491; Septin.
DR PANTHER; PTHR18884; SEPTIN; 1.
DR PANTHER; PTHR18884:SF68; SEPTIN-5; 1.
DR Pfam; PF00735; Septin; 1.
DR PIRSF; PIRSF006698; Septin; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51719; G_SEPTIN; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134, ECO:0000256|PIRSR:PIRSR006698-
KW 2}; Methylation {ECO:0000256|ARBA:ARBA00022481};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|PIRSR:PIRSR006698-2};
KW Reference proteome {ECO:0000313|Proteomes:UP000261580}.
FT DOMAIN 46..319
FT /note="Septin-type G"
FT /evidence="ECO:0000259|PROSITE:PS51719"
FT SITE 168
FT /note="Important for dimerization"
FT /evidence="ECO:0000256|PIRSR:PIRSR006698-2"
SQ SEQUENCE 376 AA; 43867 MW; AAC547DF95B6554D CRC64;
MDAIMLQEKL VERLLCPRVR TARQKEKQYV GFATLPNQVH RKSVKKGFDF TLMVAGESGM
GKSTLVNSLF LTDLYKDRKL LNAEERINQT VEIIKHTVDI EEKGVKLKLT IVDTPGFGDA
VNNNECWKPI TDYIDQQFEQ YFRDESGLNR KNIQDNRVHC CLYFIPPFGH GLRPVDVEFM
KALHEKVNII PLIAKADCLT PNEIKKLKDR IREEIDKFGI KVYQFPECDS DEDEEFKQLD
KELKECTPFA VIGSNTVVEA RGQRVRGRLY PWGIVEVENQ SHCDFVKLRN MLIRSHMHDL
KDVTCDVHYE NYRAQCIQEM TSKLAQDNRM ESPIPILPLS TPDVDTEKLI KMKDEELKRM
QEMLNKMQQQ MHDKEQ
//
