ID A0A3Q4HUG1_NEOBR Unreviewed; 489 AA.
AC A0A3Q4HUG1;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE RecName: Full=Enolase 4 {ECO:0000256|ARBA:ARBA00034855};
DE EC=4.2.1.11 {ECO:0000256|ARBA:ARBA00012058};
DE AltName: Full=2-phospho-D-glycerate hydro-lyase {ECO:0000256|ARBA:ARBA00031125};
OS Neolamprologus brichardi (Fairy cichlid) (Lamprologus brichardi).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Lamprologini; Neolamprologus.
OX NCBI_TaxID=32507 {ECO:0000313|Ensembl:ENSNBRP00000024673.1, ECO:0000313|Proteomes:UP000261580};
RN [1] {ECO:0000313|Ensembl:ENSNBRP00000024673.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- PATHWAY: Carbohydrate degradation; glycolysis; pyruvate from D-
CC glyceraldehyde 3-phosphate: step 4/5. {ECO:0000256|ARBA:ARBA00005031}.
CC -!- SIMILARITY: Belongs to the enolase family.
CC {ECO:0000256|ARBA:ARBA00009604}.
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DR AlphaFoldDB; A0A3Q4HUG1; -.
DR STRING; 32507.ENSNBRP00000024673; -.
DR Ensembl; ENSNBRT00000025322.1; ENSNBRP00000024673.1; ENSNBRG00000018850.1.
DR GeneTree; ENSGT00950000182805; -.
DR OMA; MKELICI; -.
DR UniPathway; UPA00109; UER00187.
DR Proteomes; UP000261580; Unplaced.
DR Bgee; ENSNBRG00000018850; Expressed in testis.
DR GO; GO:0000015; C:phosphopyruvate hydratase complex; IEA:InterPro.
DR GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR GO; GO:0004634; F:phosphopyruvate hydratase activity; IEA:UniProtKB-EC.
DR GO; GO:0006096; P:glycolytic process; IEA:UniProtKB-UniPathway.
DR CDD; cd22974; DD_ENO4; 1.
DR Gene3D; 3.20.20.120; Enolase-like C-terminal domain; 1.
DR Gene3D; 3.30.390.10; Enolase-like, N-terminal domain; 1.
DR InterPro; IPR047500; DD_ENO4.
DR InterPro; IPR000941; Enolase.
DR InterPro; IPR036849; Enolase-like_C_sf.
DR InterPro; IPR029017; Enolase-like_N.
DR InterPro; IPR020810; Enolase_C.
DR InterPro; IPR020811; Enolase_N.
DR PANTHER; PTHR11902; ENOLASE; 1.
DR PANTHER; PTHR11902:SF30; ENOLASE 4; 1.
DR Pfam; PF00113; Enolase_C; 1.
DR SMART; SM01192; Enolase_C; 1.
DR SMART; SM01193; Enolase_N; 1.
DR SUPFAM; SSF51604; Enolase C-terminal domain-like; 1.
DR SUPFAM; SSF54826; Enolase N-terminal domain-like; 1.
PE 3: Inferred from homology;
KW Glycolysis {ECO:0000256|ARBA:ARBA00023152};
KW Lyase {ECO:0000256|ARBA:ARBA00023239};
KW Reference proteome {ECO:0000313|Proteomes:UP000261580}.
FT DOMAIN 69..222
FT /note="Enolase N-terminal"
FT /evidence="ECO:0000259|SMART:SM01193"
FT DOMAIN 231..484
FT /note="Enolase C-terminal TIM barrel"
FT /evidence="ECO:0000259|SMART:SM01192"
SQ SEQUENCE 489 AA; 54475 MW; 8448ECDE18551C4A CRC64;
MSHPAFSKRV CEDKRDFDEM KTAAAEFYRV SRVPQDIERA LHQLFLHRPA DQHGYLADYF
ANLAAPPRIS RVTGRQVYDA RGRLSLEAEV YCVVHNKEKV KVISAVSSHL VPESQERTEH
VMAAVLWINE PLNSMLKDRD PCDQLKIDHI LSFFLCYKPE ICSKLFWDFY YITGKKSTVE
KPLPAAEPQQ PVLRGSLAVG SVSLAVAKTG AQIQGVHLYE YVAALRNQEP PFHIPVSLVT
LLSCGKTSPG KLNLLEEVIL IPKVGQQVKQ VQNRNLWLTS PSFVCDSGAL AVSHERAEQP
LDLIAEACTN LGLPLGTQIH LALNCAAHDK YIIRKYEVAT GVLKSPDELV DLYQTLISKY
PAVVALIDPF RKEDRDQWEK LSSMIGNSCS LLSDVSYKSQ GPPLPGARGH ILKHINETTV
SDLIHMTSEQ QGNNCAFLLV QAVGLGLHYV KLGGLSGAER MTKYNRLISI EEELAQQGIL
GRFFSQPSL
//
