ID   A0A3Q4HZT5_NEOBR        Unreviewed;       937 AA.
AC   A0A3Q4HZT5;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   SubName: Full=HPS3 biogenesis of lysosomal organelles complex 2 subunit 1 {ECO:0000313|Ensembl:ENSNBRP00000027846.1};
OS   Neolamprologus brichardi (Fairy cichlid) (Lamprologus brichardi).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Lamprologini; Neolamprologus.
OX   NCBI_TaxID=32507 {ECO:0000313|Ensembl:ENSNBRP00000027846.1, ECO:0000313|Proteomes:UP000261580};
RN   [1] {ECO:0000313|Ensembl:ENSNBRP00000027846.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A3Q4HZT5; -.
DR   STRING; 32507.ENSNBRP00000027846; -.
DR   Ensembl; ENSNBRT00000028572.1; ENSNBRP00000027846.1; ENSNBRG00000021182.1.
DR   GeneTree; ENSGT00390000015458; -.
DR   OMA; LCIQNTE; -.
DR   Proteomes; UP000261580; Unplaced.
DR   Bgee; ENSNBRG00000021182; Expressed in blood and 8 other cell types or tissues.
DR   InterPro; IPR017216; HPS3.
DR   InterPro; IPR029438; HPS3_C.
DR   InterPro; IPR029437; HPS3_N.
DR   PANTHER; PTHR28633; HERMANSKY-PUDLAK SYNDROME 3 PROTEIN; 1.
DR   PANTHER; PTHR28633:SF1; HERMANSKY-PUDLAK SYNDROME 3 PROTEIN; 1.
DR   Pfam; PF14763; HPS3_C; 2.
DR   Pfam; PF14761; HPS3_N; 2.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000261580}.
FT   DOMAIN          3..182
FT                   /note="BLOC-2 complex member HPS3 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF14761"
FT   DOMAIN          197..429
FT                   /note="BLOC-2 complex member HPS3 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF14761"
FT   DOMAIN          448..781
FT                   /note="BLOC-2 complex member HPS3 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF14763"
FT   DOMAIN          796..934
FT                   /note="BLOC-2 complex member HPS3 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF14763"
SQ   SEQUENCE   937 AA;  105228 MW;  A2F812866ED56820 CRC64;
     MVHVYNCHPF SSQQIVQVKL NLTDADPVSA VFYYLRSSSL LSLSTLKNLG FYHCLLCAHS
     LLGDYLVTIE EKNNATYLRA YTNWRYQAEE KARVGVRLLG HLLGGASVWG GVQMEIIEIP
     LSERPIAVSC CPVRGDLLVG SENTLVLFTL RQHNHQNLSV LDFERSVILH LPKFTPKQVL
     FFTYFYLWLC QTVISTEYLE DQADFLVVPR HQELLGDRAK DCDIPVSIEK TGLEEGRQYA
     LSYVLFRHFS PEFFQGCSMD EMQLHSLQLY PLFTGEYHIS VGSVSPDEAT CVFCFFSLPT
     TGYLYSLKGG VELLSAYQYP EKVLEAALTD HLLHVITNAL QCFTVRCAAL AARIEDPYID
     TTMKACPPSS LEVCALRMQL FIGLRSMCVY GRHVILLSAA DAETPGETER GTQRRGLSRR
     WTVSSTKESR AAGHGWNLYV VDTVTPFTLY QEMVEYSQRY AETNPQAQSL RHLLSEAHLL
     LRAALLHASD EQQTGPGGPA DHRTDRQVLE EALRENCAQL GDSFSRGGQK ECHLALPYYR
     MSGLSLTEVM SRNRPFPGSP SSYGPGFLFY LKHFLLEDSE QTLSQEAADQ VIDIFSQSEP
     VMLISVCTSP CMINVSPART LQILQNLEDS VGVSVSLTIT MATMMLRLGD LQQYTQLMER
     HAEMLLVYGF IEEPRLLLYG GCANQHRRVY PTALTRQMAD SQPGLLVAAM VALHENSKVK
     LEEADHIFKV LLAPGSAVPG GYLQVDFWEA MLMASSNDAV IQELLFRLAS VYIDRLTNTK
     SENSLFMFLY CSCLCVQSLL CGPSLSVGSV VPLLERLSDE TLWGFSLHLL CATRRGQYDR
     SIEKLLDRCP QAIIPYANHQ LQEKNMALWW QKLLPELCDR TRVASDNSIL LAALKETLVV
     VAMEMSPAEF LELIPDDGTA SYFLPHLLTC SQRQVLA
//