ID   A0A3Q4I0D2_NEOBR        Unreviewed;       630 AA.
AC   A0A3Q4I0D2;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   SubName: Full=Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E {ECO:0000313|Ensembl:ENSNBRP00000029840.1};
OS   Neolamprologus brichardi (Fairy cichlid) (Lamprologus brichardi).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Lamprologini; Neolamprologus.
OX   NCBI_TaxID=32507 {ECO:0000313|Ensembl:ENSNBRP00000029840.1, ECO:0000313|Proteomes:UP000261580};
RN   [1] {ECO:0000313|Ensembl:ENSNBRP00000029840.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC       feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00352}.
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DR   AlphaFoldDB; A0A3Q4I0D2; -.
DR   STRING; 32507.ENSNBRP00000029840; -.
DR   Ensembl; ENSNBRT00000030603.1; ENSNBRP00000029840.1; ENSNBRG00000022679.1.
DR   GeneTree; ENSGT00940000158437; -.
DR   OMA; ASECANF; -.
DR   Proteomes; UP000261580; Unplaced.
DR   Bgee; ENSNBRG00000022679; Expressed in mesonephros and 3 other cell types or tissues.
DR   GO; GO:0038191; F:neuropilin binding; IEA:Ensembl.
DR   GO; GO:0030215; F:semaphorin receptor binding; IEA:InterPro.
DR   GO; GO:0001755; P:neural crest cell migration; IEA:Ensembl.
DR   GO; GO:0022008; P:neurogenesis; IEA:UniProt.
DR   GO; GO:0002040; P:sprouting angiogenesis; IEA:Ensembl.
DR   Gene3D; 3.30.1680.10; ligand-binding face of the semaphorins, domain 2; 1.
DR   Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR   InterPro; IPR016201; PSI.
DR   InterPro; IPR001627; Semap_dom.
DR   InterPro; IPR036352; Semap_dom_sf.
DR   InterPro; IPR027231; Semaphorin.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   PANTHER; PTHR11036; SEMAPHORIN; 1.
DR   PANTHER; PTHR11036:SF22; SEMAPHORIN-3E; 1.
DR   Pfam; PF01403; Sema; 1.
DR   SMART; SM00423; PSI; 1.
DR   SMART; SM00630; Sema; 1.
DR   SUPFAM; SSF103575; Plexin repeat; 1.
DR   SUPFAM; SSF101912; Sema domain; 1.
DR   PROSITE; PS51004; SEMA; 1.
PE   4: Predicted;
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Reference proteome {ECO:0000313|Proteomes:UP000261580}.
FT   DOMAIN          1..431
FT                   /note="Sema"
FT                   /evidence="ECO:0000259|PROSITE:PS51004"
FT   REGION          549..571
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   630 AA;  71045 MW;  1FFD742E3AB96D3E CRC64;
     LNRTWVFQKH GVSLQPQTML LDEGHERLYV GAKNALFSLS LDQVNTHHAE VSLVYFLPQE
     CANYIKVLQQ YNQTHLLACG TGAFNPICAA VRDRLFALEE ESITSGRGRS PYDPNSPCTS
     ALSSKNCSTY HSTPPHLRLK VKEPKFVGSA VIPDNDDRGD DKVYFFFTER EMDAEGVTKA
     VYSRIGRVCA NDQGGQRMLV NRWTSFLKTR LICSVAGPNG IDTHFDELED VFVLNNKDEK
     NPEVFCLFST TSTVFKGYAV CVYHMDDIRA AFNGPFAFRE RPEHHWTPYE DRVPYPRPGS
     CASKVNGGGF SSSKEFPDEV LRFLRSHPVM YNPVLPQHHR PVLLQTEPGR RKLTQIAVDR
     VQAQDGHYHV LYIGTGIGTV LDCINPYTDT MEEVLLEELE VFRVPYFFAP ECESKQQLYV
     GSEVGLAQVR LHQCDLYGSE CADCCLARDP YCAWDGITCS RYYPAGVYPS RRRQDVRHGN
     AVQLCNGLAK DRLVYGVESN STLLECVPRS LQAKVLWFFQ KGGENHQDPV QYLSRRGVIA
     DAVQVRPPPL HGTAGHAPPQ SPSPSPKNTS RATNNICSRF FLFSRVKYIL GHQTHSHSAW
     VYLSQWGAEG ISEWNSCCSF IPHGYHSNRL
//