ID A0A3Q4I2B9_NEOBR Unreviewed; 1436 AA.
AC A0A3Q4I2B9;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Neurexin-3a-like {ECO:0000313|Ensembl:ENSNBRP00000027888.1};
OS Neolamprologus brichardi (Fairy cichlid) (Lamprologus brichardi).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Lamprologini; Neolamprologus.
OX NCBI_TaxID=32507 {ECO:0000313|Ensembl:ENSNBRP00000027888.1, ECO:0000313|Proteomes:UP000261580};
RN [1] {ECO:0000313|Ensembl:ENSNBRP00000027888.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR STRING; 32507.ENSNBRP00000027888; -.
DR Ensembl; ENSNBRT00000028615.1; ENSNBRP00000027888.1; ENSNBRG00000021230.1.
DR GeneTree; ENSGT00940000154618; -.
DR OMA; TDLKFGS; -.
DR Proteomes; UP000261580; Unplaced.
DR Bgee; ENSNBRG00000021230; Expressed in brain.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.
DR CDD; cd00054; EGF_CA; 2.
DR CDD; cd00110; LamG; 6.
DR Gene3D; 2.60.120.200; -; 7.
DR Gene3D; 2.10.25.10; Laminin; 3.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR001791; Laminin_G.
DR InterPro; IPR003585; Neurexin-like.
DR PANTHER; PTHR15036:SF57; NEUREXIN-3; 1.
DR PANTHER; PTHR15036; PIKACHURIN-LIKE PROTEIN; 1.
DR Pfam; PF02210; Laminin_G_2; 6.
DR SMART; SM00294; 4.1m; 1.
DR SMART; SM00181; EGF; 3.
DR SMART; SM00282; LamG; 6.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 6.
DR PROSITE; PS50026; EGF_3; 3.
DR PROSITE; PS50025; LAM_G_DOMAIN; 5.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW EGF-like domain {ECO:0000256|PROSITE-ProRule:PRU00076};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000261580};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..1436
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5018579150"
FT TRANSMEM 1362..1382
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 19..194
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 190..227
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 275..457
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 464..655
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 659..696
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 701..1017
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 1020..1057
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 1061..1261
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT REGION 1295..1357
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1406..1436
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1295..1316
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1419..1436
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1436 AA; 158582 MW; B1025E62A5AFF8A3 CRC64;
MDLVGFSIRL HVFLSTCLGL EFLGTPGQWA RYLRWDASTR GDLSFQFKTE ASDALLLYFD
DGGYCDFLQL SVAEGLLQLR FSIDCAETTV VSDRRVDDSS WHFATLSRYN LRTVLVLDGQ
AKAGEVKPQR QFMKIVSDLF LGGVPQDIRS GALTLPTVRN MQPFSGTIAD LKYGISQPLF
LGSLNVPLES EGWCTVNPCE NGGMCTVVDG EPVCDCSKTE YKGRFCSEGK APRNPAHFTC
STFCHVTTLF QNGFWGGCGS GGRADQLLIG REENVATFRG SEYFCYDLSQ NPIQSSSDEI
TLSFKTWQRN GLILHTGKSA DYVNLALKDG AVSLVINLGS GAFEAIVEPV NGKFNDNSWH
DVKVTRNLRQ VTISVDGILT TTGYTQEDYT MLGSDDFFYV GGSPSTADLP GSPVSNNFMG
CLKEVVYKNN DIRLELSRLA RIVDPKMKIQ GEVSYKCENV ATLDPISFET PEAYISLPKW
NTKRMGSISF DFRTTEPNGL ILFTHGKPQE AVGSFFSLAQ VDFFAVELLD GSLYLLLDMG
SGTIKVKATQ TKVNDGVWYH VDIQRDGRSG TISVNSRRTP FTASGESEIL DLEGDMYLGG
LPTDRTNLIL PTELWTAMLN YGYVGCIRDL FIDGRSKDIR QIAEAQNGAG IKPSCNKQPG
KQCESYPCKN RGVCKEGWNR FICDCTGTGY WSRTCEREAS ILSYDGSMYM KVVMPTIMHT
EAEDVSLRFR SQRAYGLLMA TTSRDSADTL RLELDGSRVK LTVNLDCIRI NCNSSKGPET
LYAGQKLNDN EWHTVRVVRR GKTYKLTVDD DVAEGQMVGD HTRLEFHNIE TGIMTERRFV
SSIPSSFIGH LQSLRFNGML YIDLCKNGDI DYCELNARFG IRSIIADPVT FKSKSSYLSL
ATLQAYTSMH LFFQFKTTSP DGFILFNSGD GNDFIAVELV KGYIHYVFDL GNGPNLIKGK
SDLFIAGLGP GMYGNLPKLV ASREGFQGCL ASVDLNGRLP DLLNDALFRS GQIERGCEGP
STTCQEDSCA NMGICIQQWE NYTCDCSMTS YTGTQCNDPG TTYIFGKGGG LITFNWPANE
RPSTRTDRLT VGFSTSLKDG ILVRIDSAPG LGDYLMLHIQ QGKIGVTFNI GTVDISVQES
STPVNDGKYH VVRFTRNGGN ATLQVDNWSI NEHFPPGNSD IERYQMANKK IPFKFARPVE
EWLQEKGRQL TIFNTQATVA IGGSDRGRPF QGQLSGLYYN GLKVLNMAAE GNPNIKINGS
VRLVGDVPSV AGSARSTAMS PEMTTSFIET TTMMSTTTTR KHRSSSTVQH QEDIGSSAEC
SSDDEDEEEC ETSRTALPTE PGVRRVPGPS EVVRESSSTT GMVIGIVAAA ALCILILLYA
MYKYRNRDEG SYQVDESRNY ITNSAVQSNG AVMKDKQQSL KGSNKRQKNK DKEYYV
//
