ID   A0A3Q4IE18_NEOBR        Unreviewed;       355 AA.
AC   A0A3Q4IE18;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   24-JAN-2024, entry version 22.
DE   SubName: Full=Major histocompatibility complex class I-related gene protein-like {ECO:0000313|Ensembl:ENSNBRP00000029677.1};
OS   Neolamprologus brichardi (Fairy cichlid) (Lamprologus brichardi).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Lamprologini; Neolamprologus.
OX   NCBI_TaxID=32507 {ECO:0000313|Ensembl:ENSNBRP00000029677.1, ECO:0000313|Proteomes:UP000261580};
RN   [1] {ECO:0000313|Ensembl:ENSNBRP00000029677.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the MHC class I family.
CC       {ECO:0000256|RuleBase:RU004439}.
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DR   AlphaFoldDB; A0A3Q4IE18; -.
DR   Ensembl; ENSNBRT00000030439.1; ENSNBRP00000029677.1; ENSNBRG00000021842.1.
DR   GeneTree; ENSGT01100000263475; -.
DR   Proteomes; UP000261580; Unplaced.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR   Gene3D; 3.30.500.10; MHC class I-like antigen recognition-like; 1.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR003597; Ig_C1-set.
DR   InterPro; IPR011161; MHC_I-like_Ag-recog.
DR   InterPro; IPR037055; MHC_I-like_Ag-recog_sf.
DR   InterPro; IPR011162; MHC_I/II-like_Ag-recog.
DR   InterPro; IPR001039; MHC_I_a_a1/a2.
DR   PANTHER; PTHR16675:SF237; MHC CLASS I ANTIGEN TRANSCRIPT VARIANT 1-RELATED; 1.
DR   PANTHER; PTHR16675; MHC CLASS I-RELATED; 1.
DR   Pfam; PF07654; C1-set; 1.
DR   Pfam; PF00129; MHC_I; 1.
DR   PRINTS; PR01638; MHCCLASSI.
DR   SMART; SM00407; IGc1; 1.
DR   SUPFAM; SSF48726; Immunoglobulin; 1.
DR   SUPFAM; SSF54452; MHC antigen-recognition domain; 1.
DR   PROSITE; PS50835; IG_LIKE; 1.
PE   3: Inferred from homology;
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Reference proteome {ECO:0000313|Proteomes:UP000261580};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..16
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           17..355
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5018648987"
FT   DOMAIN          195..269
FT                   /note="Ig-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50835"
SQ   SEQUENCE   355 AA;  40865 MW;  6A4EEAF174067E46 CRC64;
     MHFSFLTLLL IKHSMTVFFT ASSGVPNFPE VVAVMLNDDV EVGYCDSKLK TAIPKQDWME
     TLRDEDPKYW KLYTGECTVH QQLFKEEFHA VKKRLNQTGA VHIYQRLTCC EWDDETDKVS
     GFNLYGYDGE DFLTFNMETQ TWIGPKPQAV IIKHLWNNDS ARNIFFTNYI NQVCVYRLKT
     NLKYGMSFLL RTELPSVSLL QKTPSSSVSC HATGFYPHRA MMFWRRNGEE IHEGVNHGEI
     LPNHDGTFQM SVDLDLSTVT PEEFGNYDCV FQLSGVKKDI ITKLDKAMIR TNWAALMEYF
     LTSPAVPWHR PSRSGGQPLH QWRIRNRSGG AAVPVILHRG EWEILGSLPG SRCRH
//