ID A0A3Q4IGT3_NEOBR Unreviewed; 587 AA.
AC A0A3Q4IGT3;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE SubName: Full=Transcription factor COE3-like {ECO:0000313|Ensembl:ENSNBRP00000031797.1};
OS Neolamprologus brichardi (Fairy cichlid) (Lamprologus brichardi).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Lamprologini; Neolamprologus.
OX NCBI_TaxID=32507 {ECO:0000313|Ensembl:ENSNBRP00000031797.1, ECO:0000313|Proteomes:UP000261580};
RN [1] {ECO:0000313|Ensembl:ENSNBRP00000031797.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|RuleBase:RU004489}.
CC -!- SIMILARITY: Belongs to the COE family. {ECO:0000256|ARBA:ARBA00010340,
CC ECO:0000256|RuleBase:RU004489}.
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DR AlphaFoldDB; A0A3Q4IGT3; -.
DR STRING; 32507.ENSNBRP00000031797; -.
DR Ensembl; ENSNBRT00000032600.1; ENSNBRP00000031797.1; ENSNBRG00000024165.1.
DR GeneTree; ENSGT00950000182859; -.
DR OMA; GQVGYNR; -.
DR Proteomes; UP000261580; Unplaced.
DR Bgee; ENSNBRG00000024165; Expressed in camera-type eye and 1 other cell type or tissue.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd11606; COE_DBD; 1.
DR CDD; cd01175; IPT_COE; 1.
DR Gene3D; 1.10.287.4280; -; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 2.60.40.3180; Transcription factor COE1, DNA-binding domain; 1.
DR InterPro; IPR032200; COE_DBD.
DR InterPro; IPR038173; COE_DBD_sf.
DR InterPro; IPR032201; COE_HLH.
DR InterPro; IPR038006; COE_IPT.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR014756; Ig_E-set.
DR InterPro; IPR002909; IPT_dom.
DR InterPro; IPR003523; Transcription_factor_COE.
DR InterPro; IPR018350; Transcription_factor_COE_CS.
DR PANTHER; PTHR10747; TRANSCRIPTION FACTOR COE FAMILY MEMBER; 1.
DR PANTHER; PTHR10747:SF4; TRANSCRIPTION FACTOR COE3; 1.
DR Pfam; PF16422; COE1_DBD; 1.
DR Pfam; PF16423; COE1_HLH; 1.
DR Pfam; PF01833; TIG; 1.
DR SMART; SM00429; IPT; 1.
DR SUPFAM; SSF81296; E set domains; 1.
DR PROSITE; PS01345; COE; 1.
PE 3: Inferred from homology;
KW Developmental protein {ECO:0000256|RuleBase:RU004489};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU004489};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|RuleBase:RU004489};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU004489};
KW Reference proteome {ECO:0000313|Proteomes:UP000261580};
KW Transcription {ECO:0000256|ARBA:ARBA00023163,
KW ECO:0000256|RuleBase:RU004489};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015,
KW ECO:0000256|RuleBase:RU004489};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|RuleBase:RU004489};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|RuleBase:RU004489}.
FT DOMAIN 248..332
FT /note="IPT/TIG"
FT /evidence="ECO:0000259|SMART:SM00429"
FT REGION 444..468
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 587 AA; 63900 MW; E79A2AFEEA747BED CRC64;
MFGIQDNLPR GATANMKEEP LAVRSWMHSA GVVDANTAAQ SGVGLARAHF EKQPPSNLRK
SNFFHFVLAL YDRQGQPVEI ERTAYVDFVE KEKEPTGEKT NNGIHYKLQL LYSNGGATGD
LHFTCLCVCV QAIIYEGQDK NPEMCRVLLT HEIMCSRCCD KKSCGNRNET PSDPVIIDRF
FLKFFLKCNQ NCLKNAGNPR DMRRFQVVVS TTVNVDGHVL AVSDNMFVHN NSKHGRRARR
LDPSEAATPC IKAISPSEGW TTGGATVILI GDNFFDGLQV VFGTMLVWSE LITPHAIRVQ
TPPRHIPGVV EVTLSYKSKQ FCKGAPGRFV YTALNEPTID YGFQRLQKVI PRHPGDPERL
PKEVLLKRAA DLVEALYGMP HNNQEIILKR AADIAEALYS VPRNHNQIPS LGNTASHGMM
GVNSFSGQLA VNVSETTQGM SVGYSRNTSS VSPRGYVPSS TPQQSNYGNT VSNSMNGYGN
TGMPNLGVAT SPGFLNGSSA NSPYGIVPSS PTMAVSNCNS SHGVFSFSAA VKQKSAFAPV
VRPPASPPPP PNCSANNANG LQGETAAPWV YKLKLLLSKV SRSVRDL
//
