ID A0A3Q4M7X8_NEOBR Unreviewed; 959 AA.
AC A0A3Q4M7X8;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=B30.2/SPRY domain-containing protein {ECO:0008006|Google:ProtNLM};
OS Neolamprologus brichardi (Fairy cichlid) (Lamprologus brichardi).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Lamprologini; Neolamprologus.
OX NCBI_TaxID=32507 {ECO:0000313|Ensembl:ENSNBRP00000004129.1, ECO:0000313|Proteomes:UP000261580};
RN [1] {ECO:0000313|Ensembl:ENSNBRP00000004129.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3Q4M7X8; -.
DR STRING; 32507.ENSNBRP00000004129; -.
DR Ensembl; ENSNBRT00000004263.1; ENSNBRP00000004129.1; ENSNBRG00000003271.1.
DR GeneTree; ENSGT01100000263487; -.
DR Proteomes; UP000261580; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR CDD; cd16040; SPRY_PRY_SNTX; 1.
DR Gene3D; 2.60.120.920; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR InterPro; IPR001870; B30.2/SPRY.
DR InterPro; IPR043136; B30.2/SPRY_sf.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR029495; NACHT-assoc.
DR InterPro; IPR007111; NACHT_NTPase.
DR InterPro; IPR041267; NLRP_HD2.
DR InterPro; IPR041075; NOD2_WH.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR006574; PRY.
DR InterPro; IPR003877; SPRY_dom.
DR PANTHER; PTHR24106; NACHT, LRR AND CARD DOMAINS-CONTAINING; 1.
DR PANTHER; PTHR24106:SF151; NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 12-RELATED; 1.
DR Pfam; PF14484; FISNA; 1.
DR Pfam; PF13516; LRR_6; 2.
DR Pfam; PF05729; NACHT; 1.
DR Pfam; PF17776; NLRC4_HD2; 1.
DR Pfam; PF17779; NOD2_WH; 1.
DR Pfam; PF00622; SPRY; 1.
DR SMART; SM01288; FISNA; 1.
DR SMART; SM00368; LRR_RI; 3.
DR SMART; SM00589; PRY; 1.
DR SMART; SM00449; SPRY; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF52047; RNI-like; 1.
DR PROSITE; PS50188; B302_SPRY; 1.
DR PROSITE; PS51450; LRR; 1.
DR PROSITE; PS50837; NACHT; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000261580}.
FT DOMAIN 137..271
FT /note="NACHT"
FT /evidence="ECO:0000259|PROSITE:PS50837"
FT DOMAIN 763..959
FT /note="B30.2/SPRY"
FT /evidence="ECO:0000259|PROSITE:PS50188"
SQ SEQUENCE 959 AA; 108409 MW; 035561DAE48D9A5F CRC64;
MTENRELAQA DWLKEDNWTR VMMSVFRLTG RESSSYVDFI LSKYVLLFYP EFLLKCQPNL
KKKFQFVFGG IAKAGNPTLL NQIYIEPYIT EGGTAGVSDE HEVRQIETAS RKPDRPETTI
RQEDIFKASS VKDKPIRTVL TKGVAGIGKT VLTQKFTLDW AEDKANQDIQ FMFPFTFREL
NVLKEKKFSL VELIHHLFPE TKQAGICSFE DFQVVFIFDS LDECRLPLDF HKTSILTDVT
ESTSVDVLLI NLIRGKLLPS AHLWITTRPA AVNQIPPEYV GMVTELNGFT DPQKEEYFKK
RFRDKNQVTK IVSHIKTSRS LHIMCHIPVF CWITATVLED VLKTREGGEL PKTLTEMCIH
FLVVQAKVKK VKYDGGAETD PHWSPESRKM IESLGKLAFD QLQKGNLIFY ESDLTECGID
VRAALVYSGV FTQIFKEERG LYQDKMFCFI HLSVQEFLAA LYVHLTFINS GVNLLEKQQT
SWWSKLLQNK PKRKNLHQSA VDKALQSPHA HLDLFLRFLL GLSLHTNQIL LQGLLTQTGN
SSLNSQETVQ YIKKKLSENL SAERSINLFH CLNEINDCSL WKEIQTSLSS GSLSKQKLSP
AQWSALVFIL LSSEDLDVFD LRKYSASEEA LLRLLPVVKV TRKALLSFCK FTERSCKTLS
SVLSSQSSSL RELDLSNNDL QDPGVKLLSA GLKNPQCKLE TLSLSGCLIT KDSCASLASA
LRSNPSHLRD LDLSYNHPGD SGVALLSARL EDQQSKLKNL RYGRKCKLTA AVLCLFSLDI
CEPTPSANTI HTKIKLSDNN MKMTLVKEDQ SYPDHHDRFE LPQLLCRNGL TGRCYWEVEW
RGKVDLSVSY RGIKKKGSSN GCRFGSSDQS WSLRCSDDAC YHVWHNDETA SISSTSSSVS
HRVGVYVDCP SGTLSFYRVS SDALIHLHTF STTFTELLYP GFGFWSPGSS VSLCAVEYG
//
