ID A0A3Q4MJH7_NEOBR Unreviewed; 561 AA.
AC A0A3Q4MJH7;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE SubName: Full=Galectin-3-binding protein B-like {ECO:0000313|Ensembl:ENSNBRP00000012114.1};
OS Neolamprologus brichardi (Fairy cichlid) (Lamprologus brichardi).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Lamprologini; Neolamprologus.
OX NCBI_TaxID=32507 {ECO:0000313|Ensembl:ENSNBRP00000012114.1, ECO:0000313|Proteomes:UP000261580};
RN [1] {ECO:0000313|Ensembl:ENSNBRP00000012114.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular
CC matrix {ECO:0000256|ARBA:ARBA00004498}.
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DR AlphaFoldDB; A0A3Q4MJH7; -.
DR STRING; 32507.ENSNBRP00000012114; -.
DR Ensembl; ENSNBRT00000012455.1; ENSNBRP00000012114.1; ENSNBRG00000009430.1.
DR GeneTree; ENSGT00940000164412; -.
DR Proteomes; UP000261580; Unplaced.
DR Bgee; ENSNBRG00000009430; Expressed in zone of skin and 1 other cell type or tissue.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR CDD; cd18496; BACK_LGALS3BP; 1.
DR Gene3D; 1.25.40.420; -; 1.
DR Gene3D; 3.10.250.10; SRCR-like domain; 1.
DR InterPro; IPR011705; BACK.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR InterPro; IPR001190; SRCR.
DR InterPro; IPR017448; SRCR-like_dom.
DR InterPro; IPR036772; SRCR-like_dom_sf.
DR PANTHER; PTHR24410:SF16; GALECTIN-3-BINDING PROTEIN; 1.
DR PANTHER; PTHR24410; HL07962P-RELATED; 1.
DR Pfam; PF07707; BACK; 1.
DR Pfam; PF00530; SRCR; 1.
DR PRINTS; PR00258; SPERACTRCPTR.
DR SMART; SM00875; BACK; 1.
DR SMART; SM00202; SR; 1.
DR SUPFAM; SSF54695; POZ domain; 1.
DR SUPFAM; SSF56487; SRCR-like; 1.
DR PROSITE; PS50097; BTB; 1.
DR PROSITE; PS50287; SRCR_2; 1.
PE 4: Predicted;
KW Cell adhesion {ECO:0000256|ARBA:ARBA00022889};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00196}; Extracellular matrix {ECO:0000256|ARBA:ARBA00022530};
KW Reference proteome {ECO:0000313|Proteomes:UP000261580};
KW Secreted {ECO:0000256|ARBA:ARBA00022530}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..24
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 25..561
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5018541053"
FT DOMAIN 29..129
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 165..232
FT /note="BTB"
FT /evidence="ECO:0000259|PROSITE:PS50097"
FT DISULFID 54..118
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 67..128
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 98..108
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
SQ SEQUENCE 561 AA; 63279 MW; 80AB6F8AE6A371EE CRC64;
MTLQTLRRLW LVIIICRYLK MTIKQKGYIR LAGGQEYSEG RVEIFHDGVW GTICDDGWDI
NDAHVACRQL RFPGAAEAPG SAAFGAGAGN IWMDDLTCGG SEINLLQCTF PGWGVHNCGH
GEDAGVRCEK GAEPQSRDLN HEYTLDHNAS LFQQLGELFD SRQDCDVDIA VAVDNNIVET
ICAHRVILSL NSNLKALHPD LSSLLINVSS DCSQHADIFV RYFYTRKITV TLASSHCILK
MASDWGLTEY HNEAANLFRR FLPEDPTFQS QNSLYEYAVR RSDDTLQQLC LRYLAWNCEA
LINSPAWTSL PFNLVKALLS RSDLVVRNET VVLSGLERWA EARGNATMRE ILLNLVRFPM
IPAEDLYSLD SSEYHASKLE GFQFNALPVK MLLSDLTGTI YTPRIYNGRP WSFTFSSQEI
GAYQHSGVYI LRGQRVSSLK SDFQTPVHNS AYFAFHTMRW KVTAYVREED CTKQSVTCAS
LPAISLKIEE KNLPSEMEGR IRYSNRLVLM CAGRHVFHVN EFNAVDSDSP IAVPSISEQV
YPCHSNLFSY QVVVRPQYST D
//
