ID A0A3Q4MLY4_NEOBR Unreviewed; 518 AA.
AC A0A3Q4MLY4;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=Tubulin-specific chaperone E {ECO:0000256|ARBA:ARBA00015004};
DE AltName: Full=Tubulin-folding cofactor E {ECO:0000256|ARBA:ARBA00030180};
OS Neolamprologus brichardi (Fairy cichlid) (Lamprologus brichardi).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Lamprologini; Neolamprologus.
OX NCBI_TaxID=32507 {ECO:0000313|Ensembl:ENSNBRP00000014149.1, ECO:0000313|Proteomes:UP000261580};
RN [1] {ECO:0000313|Ensembl:ENSNBRP00000014149.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the TBCE family.
CC {ECO:0000256|ARBA:ARBA00006286}.
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DR AlphaFoldDB; A0A3Q4MLY4; -.
DR STRING; 32507.ENSNBRP00000014149; -.
DR Ensembl; ENSNBRT00000014534.1; ENSNBRP00000014149.1; ENSNBRG00000010949.1.
DR GeneTree; ENSGT00530000063405; -.
DR OMA; SEESHMF; -.
DR Proteomes; UP000261580; Unplaced.
DR Bgee; ENSNBRG00000010949; Expressed in blood and 9 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR CDD; cd17044; Ubl_TBCE; 1.
DR Gene3D; 2.30.30.190; CAP Gly-rich-like domain; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR InterPro; IPR036859; CAP-Gly_dom_sf.
DR InterPro; IPR000938; CAP-Gly_domain.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR InterPro; IPR044079; Ubl_TBCE.
DR PANTHER; PTHR46652; LEUCINE-RICH REPEAT AND IQ DOMAIN-CONTAINING PROTEIN 1-RELATED; 1.
DR PANTHER; PTHR46652:SF3; LEUCINE-RICH REPEAT-CONTAINING PROTEIN 9 ISOFORM X1; 1.
DR Pfam; PF01302; CAP_GLY; 1.
DR SMART; SM01052; CAP_GLY; 1.
DR SUPFAM; SSF74924; Cap-Gly domain; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 1.
DR PROSITE; PS00845; CAP_GLY_1; 1.
DR PROSITE; PS50245; CAP_GLY_2; 1.
DR PROSITE; PS51450; LRR; 1.
PE 3: Inferred from homology;
KW Chaperone {ECO:0000256|ARBA:ARBA00023186};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Reference proteome {ECO:0000313|Proteomes:UP000261580}.
FT DOMAIN 30..74
FT /note="CAP-Gly"
FT /evidence="ECO:0000259|PROSITE:PS50245"
SQ SEQUENCE 518 AA; 57272 MW; 9A1D412E4EF1C2B6 CRC64;
MGVDEAEVPV DAVGKRVSCG GERATVRYFG PVSPTAGLWL GVEWDNPDRG KHDGSHEGVQ
YFTCRQPTGG SFVRPAKVSF GVDYLTAVRQ AYKIDSEEVL SEEISISKKK LKWGNIKERG
FESLPSVLLS RSDVSWSGAD GEIRTTTPNV EWLDLSGTLL SCWEDVATIS QQLDRLGGLQ
LSYNRLRLPP DPSALRHAFS ALKVLVLNGC QLTWPQILDC APMWPQLEDL CVEENSITEL
QRPEGRLQSL KSLSLSSNPL VQDSVLSLSA LPRLEQLNLS KTGLSVIRFE DAAPGSHTAM
YAALKNLNLD HNNITEWFVV DELAKLPSLV RLSCRGNKLV SRDGNPKTAN QMLIAKLGQL
VVLNGCEIHA DDRRGAELDY MKMFGEEWLK AGGRSQPSPQ FICEHPRYQA LISKYGAPED
GELRKPEPFA LKNQLLKVTF VFPDDANRKP LEKKLPASMV VQKVKGLLYR LLKVPAADLR
LTYTSPKVAH SVKAAAHTRS PVFLCLCLHV QSEHATVG
//
