ID A0A3Q4MML8_NEOBR Unreviewed; 289 AA.
AC A0A3Q4MML8;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Ankyrin repeat and SOCS box protein 8-like {ECO:0000313|Ensembl:ENSNBRP00000014639.1};
OS Neolamprologus brichardi (Fairy cichlid) (Lamprologus brichardi).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Lamprologini; Neolamprologus.
OX NCBI_TaxID=32507 {ECO:0000313|Ensembl:ENSNBRP00000014639.1, ECO:0000313|Proteomes:UP000261580};
RN [1] {ECO:0000313|Ensembl:ENSNBRP00000014639.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
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DR RefSeq; XP_006785656.1; XM_006785593.1.
DR AlphaFoldDB; A0A3Q4MML8; -.
DR STRING; 32507.ENSNBRP00000014639; -.
DR Ensembl; ENSNBRT00000015034.1; ENSNBRP00000014639.1; ENSNBRG00000011324.1.
DR GeneID; 102793239; -.
DR CTD; 140461; -.
DR GeneTree; ENSGT00940000159366; -.
DR OMA; LHCACMA; -.
DR OrthoDB; 4022749at2759; -.
DR UniPathway; UPA00143; -.
DR Proteomes; UP000261580; Unplaced.
DR Bgee; ENSNBRG00000011324; Expressed in blood and 6 other cell types or tissues.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 3.
DR Gene3D; 1.10.750.20; SOCS box; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR001496; SOCS_box.
DR InterPro; IPR036036; SOCS_box-like_dom_sf.
DR PANTHER; PTHR24134:SF30; ANKYRIN REPEAT AND SOCS BOX PROTEIN 8; 1.
DR PANTHER; PTHR24134; ANKYRIN REPEAT-CONTAINING PROTEIN DDB_G0279043; 1.
DR Pfam; PF12796; Ank_2; 1.
DR Pfam; PF13637; Ank_4; 1.
DR Pfam; PF07525; SOCS_box; 1.
DR SMART; SM00248; ANK; 5.
DR SMART; SM00969; SOCS_box; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF158235; SOCS box-like; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 3.
DR PROSITE; PS50088; ANK_REPEAT; 3.
DR PROSITE; PS50225; SOCS; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW Reference proteome {ECO:0000313|Proteomes:UP000261580}.
FT REPEAT 52..84
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 117..149
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 150..182
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 236..289
FT /note="SOCS box"
FT /evidence="ECO:0000259|PROSITE:PS50225"
SQ SEQUENCE 289 AA; 32045 MW; 171219EB870F925B CRC64;
MSSTMWYIMQ SIQSKYSLSE RLIRTIAAIR SFPHDNVEDL IRKGADVNRM HGTLKPLHCA
CMVADADCVE LLLEKGAEVN ALDGYNRTAL HYAAEKDESC VELLLEYGAQ PNALDGNKDT
PLHWAAFKDN PECVRALLES GACPNARDYN NDTPLSWAAM KGNLESVKVL LDYGAQVHVT
NLKGQTPISR LVALLARGLG TEQEEECLEL LCRAAGRFEI RRADGTLPRE LSKDPQLLAR
LTNMVAQAPT LRSLARCAVR QSLGVQFLPT AVKELPLPET IKDYLLLRD
//
