ID   A0A3Q4MP07_NEOBR        Unreviewed;       840 AA.
AC   A0A3Q4MP07;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   SubName: Full=Leiomodin-3-like {ECO:0000313|Ensembl:ENSNBRP00000015649.1};
GN   Name=FRMD4B {ECO:0000313|Ensembl:ENSNBRP00000015649.1};
OS   Neolamprologus brichardi (Fairy cichlid) (Lamprologus brichardi).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Lamprologini; Neolamprologus.
OX   NCBI_TaxID=32507 {ECO:0000313|Ensembl:ENSNBRP00000015649.1, ECO:0000313|Proteomes:UP000261580};
RN   [1] {ECO:0000313|Ensembl:ENSNBRP00000015649.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A3Q4MP07; -.
DR   STRING; 32507.ENSNBRP00000015649; -.
DR   Ensembl; ENSNBRT00000016074.1; ENSNBRP00000015649.1; ENSNBRG00000011966.1.
DR   GeneTree; ENSGT01020000230354; -.
DR   Proteomes; UP000261580; Unplaced.
DR   Bgee; ENSNBRG00000011966; Expressed in muscle tissue and 3 other cell types or tissues.
DR   GO; GO:0005856; C:cytoskeleton; IEA:InterPro.
DR   GO; GO:0090162; P:establishment of epithelial cell polarity; IEA:InterPro.
DR   CDD; cd13191; FERM_C_FRMD4A_FRMD4B; 1.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR   InterPro; IPR019749; Band_41_domain.
DR   InterPro; IPR021774; CUPID.
DR   InterPro; IPR019747; FERM_CS.
DR   InterPro; IPR000299; FERM_domain.
DR   InterPro; IPR018979; FERM_N.
DR   InterPro; IPR018980; FERM_PH-like_C.
DR   InterPro; IPR047176; FRMD4A/B.
DR   InterPro; IPR041785; FRMD4A/B_FERM_C.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR029071; Ubiquitin-like_domsf.
DR   PANTHER; PTHR46079; FERM DOMAIN-CONTAINING PROTEIN 4; 1.
DR   PANTHER; PTHR46079:SF1; FERM DOMAIN-CONTAINING PROTEIN 4B; 1.
DR   Pfam; PF11819; CUPID; 1.
DR   Pfam; PF09380; FERM_C; 1.
DR   Pfam; PF09379; FERM_N; 1.
DR   SMART; SM00295; B41; 1.
DR   SMART; SM01196; FERM_C; 1.
DR   SUPFAM; SSF50729; PH domain-like; 1.
DR   SUPFAM; SSF54236; Ubiquitin-like; 1.
DR   PROSITE; PS00660; FERM_1; 1.
DR   PROSITE; PS50057; FERM_3; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000261580}.
FT   DOMAIN          1..261
FT                   /note="FERM"
FT                   /evidence="ECO:0000259|PROSITE:PS50057"
FT   REGION          496..561
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          703..725
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          814..840
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          315..349
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        496..513
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        530..547
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        826..840
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   840 AA;  95853 MW;  474913800B72F9D0 CRC64;
     MTEGKLCQVH LLDDRKLELL VQPKLLSYEL LDLVSSHFNL KEKEFFGLAF FDDGQCKWLQ
     MDRRVLDHDF SKKPGPIALN FLVFYVENIT QLKDIITVEL FYLNAKSAVY EAKGDYTDEN
     TRADLKKLPT LPTKVLKEHP SLAYYLTLVE SLPTYGVHYY EVKDKQGIPW WLGISYKGIG
     QYDLQDKLKP RKQLYQWKQL ENLYFREKKF AVEVNDPHRA VTKRTFGQTG LLIHTWYASH
     SLIKTIWVMA ISQHQFYLDR KQSKAKLGTT RILEEIAMDL TEHGGAKINR LGDVGLKNNF
     ITASNGSLVS TSVDSEMSEE QKKEKLTELR KKEQEIQDIL AKKTKELKKI CLREAELTGK
     LPKEYPLSSG ERPPQVRRRV GTAFKLDDLF PYNEQDPILR NLESRFALQQ KIVEAAKKLA
     NEPELCKTVK KKRRRNCLDA MHKLQQIEDE MNQYRIKKGK KPTQRASVII SNCSSLSSLP
     LDDGFRLAVD GQEASNYYQN PREVSSTHSS PYKTLPRPPR DPRSMPPTPV MTRNAYSSSQ
     LRHRSGSLES QPRLRKDRDS EKPVFILSPA HRSNSTEVLE DCSSYTSQSS LDYCGAANSH
     YSTLDSRTST MHRLHRKVEV YGNTGSMPNL VQHHSGCSYS CEASPHYAPS AYYVAGYPCP
     DMEPYANGAY VYENEVEGHY NVNPSYQMNG YHGHDRFRHY SSDGADNLSQ NPYATVRPPR
     TREGPRNELL AKNMQKALVA EHLRGWYHRN RGHREGGRGL LAGYDFDSGS QLSLGYQTMP
     AAFSHSSRAT SFSSSSAEST GNWRNQLAVG LTEFDAPDTP QYPHPGASAS LYNRSPTHNR
//