ID   A0A3Q4MPU2_NEOBR        Unreviewed;       250 AA.
AC   A0A3Q4MPU2;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   SubName: Full=DLA class II histocompatibility antigen, DR-1 beta chain-like {ECO:0000313|Ensembl:ENSNBRP00000016249.1};
OS   Neolamprologus brichardi (Fairy cichlid) (Lamprologus brichardi).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Lamprologini; Neolamprologus.
OX   NCBI_TaxID=32507 {ECO:0000313|Ensembl:ENSNBRP00000016249.1, ECO:0000313|Proteomes:UP000261580};
RN   [1] {ECO:0000313|Ensembl:ENSNBRP00000016249.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A3Q4MPU2; -.
DR   Ensembl; ENSNBRT00000016684.1; ENSNBRP00000016249.1; ENSNBRG00000012367.1.
DR   GeneTree; ENSGT00950000183127; -.
DR   Proteomes; UP000261580; Unplaced.
DR   GO; GO:0042613; C:MHC class II protein complex; IEA:InterPro.
DR   GO; GO:0019882; P:antigen processing and presentation; IEA:InterPro.
DR   GO; GO:0006955; P:immune response; IEA:InterPro.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR003597; Ig_C1-set.
DR   InterPro; IPR011162; MHC_I/II-like_Ag-recog.
DR   InterPro; IPR014745; MHC_II_a/b_N.
DR   InterPro; IPR000353; MHC_II_b_N.
DR   PANTHER; PTHR19944:SF106; DLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DR-1 BETA CHAIN-LIKE-RELATED; 1.
DR   PANTHER; PTHR19944; MHC CLASS II-RELATED; 1.
DR   Pfam; PF07654; C1-set; 1.
DR   Pfam; PF00969; MHC_II_beta; 1.
DR   SMART; SM00407; IGc1; 1.
DR   SMART; SM00921; MHC_II_beta; 1.
DR   SUPFAM; SSF48726; Immunoglobulin; 1.
DR   SUPFAM; SSF54452; MHC antigen-recognition domain; 1.
DR   PROSITE; PS50835; IG_LIKE; 1.
PE   4: Predicted;
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000261580};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        207..228
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          101..194
FT                   /note="Ig-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50835"
SQ   SEQUENCE   250 AA;  28173 MW;  D40221D433169899 CRC64;
     AITGEICSLF LVLQHFGLTE DKKNMSISIL ANYDVVYLAQ VYLNKMLLGQ YNSTLGKYVG
     YTEKTKEIAD NLNKNKGFLE HEKKNKEKCR TNIPLLCLFF PPVKPIVRLR LVESADSKHP
     GLFMCSAYNF YPKQIKLTWL RDGKEATSNV TSTDELPNGN WLYQIHSYIE ISSKPGEKIS
     CVVKHASLTE PKVYDWVPIT EAGKNKIAVG AAGLLLALVF PIIGVIFYKR KATGCIQPRT
     PQNTIKIELK
//