ID A0A3Q4MS79_NEOBR Unreviewed; 956 AA.
AC A0A3Q4MS79;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=B30.2/SPRY domain-containing protein {ECO:0008006|Google:ProtNLM};
OS Neolamprologus brichardi (Fairy cichlid) (Lamprologus brichardi).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Lamprologini; Neolamprologus.
OX NCBI_TaxID=32507 {ECO:0000313|Ensembl:ENSNBRP00000018139.1, ECO:0000313|Proteomes:UP000261580};
RN [1] {ECO:0000313|Ensembl:ENSNBRP00000018139.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3Q4MS79; -.
DR STRING; 32507.ENSNBRP00000018139; -.
DR Ensembl; ENSNBRT00000018628.1; ENSNBRP00000018139.1; ENSNBRG00000013981.1.
DR GeneTree; ENSGT01100000263487; -.
DR OMA; INCRCIV; -.
DR Proteomes; UP000261580; Unplaced.
DR Bgee; ENSNBRG00000013981; Expressed in blood and 3 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR CDD; cd16040; SPRY_PRY_SNTX; 1.
DR Gene3D; 2.60.120.920; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR InterPro; IPR001870; B30.2/SPRY.
DR InterPro; IPR043136; B30.2/SPRY_sf.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR029495; NACHT-assoc.
DR InterPro; IPR007111; NACHT_NTPase.
DR InterPro; IPR041267; NLRP_HD2.
DR InterPro; IPR041075; NOD2_WH.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR006574; PRY.
DR InterPro; IPR003877; SPRY_dom.
DR PANTHER; PTHR24106; NACHT, LRR AND CARD DOMAINS-CONTAINING; 1.
DR PANTHER; PTHR24106:SF151; NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 12-RELATED; 1.
DR Pfam; PF14484; FISNA; 1.
DR Pfam; PF13516; LRR_6; 2.
DR Pfam; PF05729; NACHT; 1.
DR Pfam; PF17776; NLRC4_HD2; 1.
DR Pfam; PF17779; NOD2_WH; 1.
DR Pfam; PF13765; PRY; 1.
DR Pfam; PF00622; SPRY; 1.
DR SMART; SM01288; FISNA; 1.
DR SMART; SM00368; LRR_RI; 1.
DR SMART; SM00449; SPRY; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF52047; RNI-like; 1.
DR PROSITE; PS50188; B302_SPRY; 1.
DR PROSITE; PS50837; NACHT; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000261580}.
FT DOMAIN 104..238
FT /note="NACHT"
FT /evidence="ECO:0000259|PROSITE:PS50837"
FT DOMAIN 744..948
FT /note="B30.2/SPRY"
FT /evidence="ECO:0000259|PROSITE:PS50188"
SQ SEQUENCE 956 AA; 107811 MW; 1495124A9F3E8ABA CRC64;
MKRNDMADCL QNKLFAPQCQ RKLKSNLKEK SQCVFEGIAK AGNQTLLNQI YTELYITEGG
TVEVNNEHEV RQLATASRKP DRTETTIRRE DIFKKSPGRD EPIRTVLTKG VAGIGKTVLI
QKFTLDWAEE QANQDIQFTF PFTFRELNVL KEKKFSLVGL VHHFFTETKK AGICWFEHFQ
VVFILDGLDE CRLPLDFHRN ETLTDITQSA SVGVLLTNLI RGKLLPSARV WITTRPAAAS
QIPPEFVHMV TEVRGFTDEQ KEEYFRKRFR DEEQASRIIS HIKSSRSLHI MCHIPVFCWI
TATVLEDMLK TREGGILPKT LTEMYIYFLV VQSKVRKIKY DGGAETDCHW GPESKKMIES
LGKLAFDQLE KGNLIFYKSD LKECGIDIRA ASVYSGVFTQ IFKEERGLYQ DTVFCFIHLS
VQEFLAALHV HLTFINSGVS VLPEEQTASQ TSETPKNKIV KTDFYQRAVD NALQSPNGHL
DLFLRFLLGL SLQSNQDLIK GLQTQTESSS ETNQKTVQYI KMKISENLSA EKSINLFHCL
NELNDRSLVE EIQQSLSSRT LSVDKLSTAQ WSALVFILLS SENDLDEFVL KKYSASEEAL
LRLLPVIKAS KKAILTDCNL SKTSCEALTS VLSNPVSSLL RELDLNNNNL KDTGVKALST
GLESQHCKLE TLRLRLASAI NNSTSAYYCF SSLSSLILCA SRLSGCLITK DGCASLVSAL
NSNPSHLKVL DLSYNHPDDA GVELQTGINC RCIVSLFLTD LSKLTVNTNT INKNLRLSMN
NMKVTHTRNN FIYPDHADRF VDWCQLLCKD VLHGRRYWEV EWTGEVDISV SYRGIGRKGE
RKNCRFGENP QSWSLDCSNA RGYTVYHNQR ISVIHPSSSS SPSCGPKRVA VYVDCPAGTL
SFYNVSSDSL IHLHTFNTTF TEPLYPGFGV WHHSCGSSVR LCSVQVEVSP SVREAV
//
