ID   A0A3Q4MYQ6_NEOBR        Unreviewed;       906 AA.
AC   A0A3Q4MYQ6;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   SubName: Full=Sorbin and SH3 domain-containing protein 1-like {ECO:0000313|Ensembl:ENSNBRP00000022634.1};
OS   Neolamprologus brichardi (Fairy cichlid) (Lamprologus brichardi).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Lamprologini; Neolamprologus.
OX   NCBI_TaxID=32507 {ECO:0000313|Ensembl:ENSNBRP00000022634.1, ECO:0000313|Proteomes:UP000261580};
RN   [1] {ECO:0000313|Ensembl:ENSNBRP00000022634.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A3Q4MYQ6; -.
DR   Ensembl; ENSNBRT00000023230.1; ENSNBRP00000022634.1; ENSNBRG00000017256.1.
DR   GeneTree; ENSGT00940000158658; -.
DR   Proteomes; UP000261580; Unplaced.
DR   Bgee; ENSNBRG00000017256; Expressed in heart and 8 other cell types or tissues.
DR   CDD; cd11780; SH3_Sorbs_3; 1.
DR   Gene3D; 2.30.30.40; SH3 Domains; 3.
DR   InterPro; IPR036028; SH3-like_dom_sf.
DR   InterPro; IPR001452; SH3_domain.
DR   InterPro; IPR003127; SoHo_dom.
DR   PANTHER; PTHR14167; SH3 DOMAIN-CONTAINING; 1.
DR   PANTHER; PTHR14167:SF64; SORBIN AND SH3 DOMAIN-CONTAINING PROTEIN 1; 1.
DR   Pfam; PF00018; SH3_1; 1.
DR   Pfam; PF07653; SH3_2; 1.
DR   Pfam; PF14604; SH3_9; 1.
DR   Pfam; PF02208; Sorb; 1.
DR   PRINTS; PR00452; SH3DOMAIN.
DR   SMART; SM00326; SH3; 3.
DR   SMART; SM00459; Sorb; 1.
DR   SUPFAM; SSF50044; SH3-domain; 3.
DR   PROSITE; PS50002; SH3; 3.
DR   PROSITE; PS50831; SOHO; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000261580};
KW   SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW   ProRule:PRU00192}.
FT   DOMAIN          158..216
FT                   /note="SoHo"
FT                   /evidence="ECO:0000259|PROSITE:PS50831"
FT   DOMAIN          463..522
FT                   /note="SH3"
FT                   /evidence="ECO:0000259|PROSITE:PS50002"
FT   DOMAIN          537..598
FT                   /note="SH3"
FT                   /evidence="ECO:0000259|PROSITE:PS50002"
FT   DOMAIN          845..906
FT                   /note="SH3"
FT                   /evidence="ECO:0000259|PROSITE:PS50002"
FT   REGION          43..114
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          127..161
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          238..356
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          371..430
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          601..624
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          711..763
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          776..798
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        44..68
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        75..114
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        271..294
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        306..331
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        332..356
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        375..389
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        390..428
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        714..732
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        733..761
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   906 AA;  100383 MW;  2250CF4E3E1B8EBA CRC64;
     MKGSPDLIPT PDLDPSRVCK GKGVVTLRAT LVHIDDEDCI SDEPNVISTP SGWTSQINGD
     SSKAGLAEGG SNDTADLPPV SNTLCQNNSS ESIKENQAPF STDIQNSVTS TPSSVYPCTS
     IVNPTIVLLQ HNRDPTPERD KSPESRSETV SPVPEMDGKR QRLSLHSPVL SPLNKPIVPN
     TEKSKDWYKT MFKQIHKIPE PIEENPYRPT YIFPESYEIQ VKSKDDGPTP FGYLEDVRAV
     PRSKSENEVD SRGCSMPVPM RSSSLKPSAK RNEWEPPDKK VDTRKYRAEP KSIFEYEPGK
     SSVLKLERTS APSFSPLETA SDLQQYSSSK SGHSEVEKDR GSSTDEPVAP ECDRHVYKSV
     LEGGDIPLQG LRALNKRPGS SSSSKDSSPA HGESQDEVLR RRHGDKEKIL EEQRRLKREQ
     EEADTASRRH TSIVPTHHQF ITNERFGDLL NITDNTEKRK SGIEKTPAMA RFDFRAETLK
     ELPFQKGDIV YIIRQVDQNW YEGEHHGRVG IFPRSYVELL PPTEKAQPKK CAPVQVLEYG
     EAVARFNFTG DTVVEMSFRK GERITLIRRV DENWYEGKIS GTNRQGIFPV TYVEVHKRPR
     VKNGVEYPDP PVSHSPQRST NASPQLYRNR LTTSPLPLPC SPRRSVSPEV HAVSSEWISL
     TVGGGSPPAA PTPPLPPLPT VSYRWGEYLP PPFSASPVPP ITGSPYCVSP MASPSASPLP
     PPYPPRPNST TPSLTFTPPQ GVDFLLSPSS PHVSRSVSPS SGPVLECWLR GEKELTEGEG
     AEGDRGRAGP GSRQNSPAEF VKNEADHHGR STRSPVMLFD IQDNNNVNSF AQPQSHSSSP
     EPSRLNCGIF QALYSYVPQN DDELELQEGD LVSVMEKCDD GWFVGTSKRT KQFGTFPGNY
     VKEVKL
//