ID   A0A3Q4MZC8_NEOBR        Unreviewed;       431 AA.
AC   A0A3Q4MZC8;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=Acyl-coenzyme A thioesterase 2, mitochondrial-like {ECO:0000313|Ensembl:ENSNBRP00000023129.1};
OS   Neolamprologus brichardi (Fairy cichlid) (Lamprologus brichardi).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Lamprologini; Neolamprologus.
OX   NCBI_TaxID=32507 {ECO:0000313|Ensembl:ENSNBRP00000023129.1, ECO:0000313|Proteomes:UP000261580};
RN   [1] {ECO:0000313|Ensembl:ENSNBRP00000023129.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the C/M/P thioester hydrolase family.
CC       {ECO:0000256|ARBA:ARBA00006538}.
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DR   AlphaFoldDB; A0A3Q4MZC8; -.
DR   Ensembl; ENSNBRT00000023731.1; ENSNBRP00000023129.1; ENSNBRG00000017617.1.
DR   GeneTree; ENSGT01010000222336; -.
DR   Proteomes; UP000261580; Unplaced.
DR   Bgee; ENSNBRG00000017617; Expressed in liver and 6 other cell types or tissues.
DR   GO; GO:0016790; F:thiolester hydrolase activity; IEA:InterPro.
DR   GO; GO:0006637; P:acyl-CoA metabolic process; IEA:InterPro.
DR   Gene3D; 2.60.40.2240; Acyl-CoA thioester hydrolase/BAAT N-terminal domain; 1.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR016662; Acyl-CoA_thioEstase_long-chain.
DR   InterPro; IPR014940; BAAT_C.
DR   InterPro; IPR006862; Thio_Ohase/aa_AcTrfase.
DR   InterPro; IPR042490; Thio_Ohase/BAAT_N.
DR   PANTHER; PTHR10824:SF17; ACYL-COENZYME A THIOESTERASE 6; 1.
DR   PANTHER; PTHR10824; ACYL-COENZYME A THIOESTERASE-RELATED; 1.
DR   Pfam; PF08840; BAAT_C; 1.
DR   Pfam; PF04775; Bile_Hydr_Trans; 1.
DR   PIRSF; PIRSF016521; Acyl-CoA_hydro; 1.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000261580}.
FT   DOMAIN          33..156
FT                   /note="Acyl-CoA thioester hydrolase/bile acid-CoA amino
FT                   acid N-acetyltransferase"
FT                   /evidence="ECO:0000259|Pfam:PF04775"
FT   DOMAIN          212..421
FT                   /note="BAAT/Acyl-CoA thioester hydrolase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF08840"
FT   ACT_SITE        241
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR016521-1"
FT   ACT_SITE        336
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR016521-1"
FT   ACT_SITE        370
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR016521-1"
SQ   SEQUENCE   431 AA;  47884 MW;  EC81278B8BB0FAFD CRC64;
     FVTKLKCNFQ PLKFHMSNQI RLRLLPSTRC LFDEPVQLKV AGLRSRQVVT IKATSTDERE
     VVFGSSATYR ADDGGEVDLN RDPSLNGSYV GVQPMGLLQS LKADTLHKYF FKNKALKPHV
     VKFSVHEQEA DGRILAEETN ERFLMGDGVS RDPIKEGNIR GVLFTPPGEG PFPAVLDLGT
     FMSEKRACLL ANKGFLVLTI AVFSDRQNMK EIHLDPFKEA VDFLRHHPKA GSKGVGIISR
     SKGTDIALSL AAFVPGVEAL VWINGTSASV GTPLYYKKQQ ILSPLMFDFS KVITTKSGAN
     LIKYATDDPL EEKNKGSLVP IERAKSQFLF VAAEDDLNWD SKDYMDEMVE RLKRCGKENF
     ETVFYPGAGH LLEPPYGPFC SSALHGMLSF SVVWGGEPRA HAAAEIHLWK KIQEFFRTHL
     SCDAAQAKAN L
//