ID   A0A3Q4N0V6_NEOBR        Unreviewed;       325 AA.
AC   A0A3Q4N0V6;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   RecName: Full=Protein Wnt {ECO:0000256|RuleBase:RU003500};
GN   Name=WNT8A {ECO:0000313|Ensembl:ENSNBRP00000024184.1};
OS   Neolamprologus brichardi (Fairy cichlid) (Lamprologus brichardi).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Lamprologini; Neolamprologus.
OX   NCBI_TaxID=32507 {ECO:0000313|Ensembl:ENSNBRP00000024184.1, ECO:0000313|Proteomes:UP000261580};
RN   [1] {ECO:0000313|Ensembl:ENSNBRP00000024184.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- FUNCTION: Ligand for members of the frizzled family of seven
CC       transmembrane receptors. {ECO:0000256|RuleBase:RU003500}.
CC   -!- SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular
CC       matrix {ECO:0000256|ARBA:ARBA00004498, ECO:0000256|RuleBase:RU003500}.
CC   -!- SIMILARITY: Belongs to the Wnt family. {ECO:0000256|ARBA:ARBA00005683,
CC       ECO:0000256|RuleBase:RU003500}.
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DR   AlphaFoldDB; A0A3Q4N0V6; -.
DR   Ensembl; ENSNBRT00000024819.1; ENSNBRP00000024184.1; ENSNBRG00000018339.1.
DR   GeneTree; ENSGT00940000157840; -.
DR   OMA; GHAWVAS; -.
DR   Proteomes; UP000261580; Unplaced.
DR   Bgee; ENSNBRG00000018339; Expressed in brain.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR   GO; GO:0005102; F:signaling receptor binding; IEA:InterPro.
DR   GO; GO:0048513; P:animal organ development; IEA:UniProt.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.2460.20; -; 1.
DR   InterPro; IPR005817; Wnt.
DR   InterPro; IPR013301; Wnt8.
DR   InterPro; IPR043158; Wnt_C.
DR   PANTHER; PTHR12027:SF92; PROTEIN WNT-8A; 1.
DR   PANTHER; PTHR12027; WNT RELATED; 1.
DR   Pfam; PF00110; wnt; 1.
DR   PRINTS; PR01892; WNT8PROTEIN.
DR   PRINTS; PR01349; WNTPROTEIN.
DR   SMART; SM00097; WNT1; 1.
PE   3: Inferred from homology;
KW   Developmental protein {ECO:0000256|ARBA:ARBA00022473,
KW   ECO:0000256|RuleBase:RU003500};
KW   Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW   Extracellular matrix {ECO:0000256|ARBA:ARBA00022530};
KW   Lipoprotein {ECO:0000256|ARBA:ARBA00023288};
KW   Reference proteome {ECO:0000313|Proteomes:UP000261580};
KW   Secreted {ECO:0000256|ARBA:ARBA00022525};
KW   Wnt signaling pathway {ECO:0000256|ARBA:ARBA00022687,
KW   ECO:0000256|RuleBase:RU003500}.
SQ   SEQUENCE   325 AA;  35939 MW;  B7A11D51063670BD CRC64;
     MNNFLMTGPK DYLTYAKSVQ VGTQIGVDEC KRQFAWDRWN CPDSATQLKG LKRATGETAF
     VHAISSAGVM YTLTRNCSLG ELENCGCDGS KNGKLGGRGW LWGGCSANVE FGERISKEYV
     DAEETGQDSR AAVNLHNNAA GRLAVKDTMT RICRCHGMSE SCSVKTCWTQ LSDFRAVGNY
     LRIKYSHAEK LDIDQKRMNA GNSADIQGAI MDALGSIAQS ELIYLQDSPD YCRKNASLGA
     HGTEGRECLL HGRGLTQGER RSCRRLCHEC GLRVEEKRTE VMSSCNCKFH WCCKVHCEDC
     AHVTVKHVCG RKDGGDGKRR DRGPK
//