ID A0A3Q4N5P7_NEOBR Unreviewed; 1020 AA.
AC A0A3Q4N5P7;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE SubName: Full=Synemin-like {ECO:0000313|Ensembl:ENSNBRP00000027544.1};
OS Neolamprologus brichardi (Fairy cichlid) (Lamprologus brichardi).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Lamprologini; Neolamprologus.
OX NCBI_TaxID=32507 {ECO:0000313|Ensembl:ENSNBRP00000027544.1, ECO:0000313|Proteomes:UP000261580};
RN [1] {ECO:0000313|Ensembl:ENSNBRP00000027544.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the intermediate filament family.
CC {ECO:0000256|RuleBase:RU000685}.
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DR RefSeq; XP_006789447.1; XM_006789384.1.
DR AlphaFoldDB; A0A3Q4N5P7; -.
DR STRING; 32507.ENSNBRP00000027544; -.
DR Ensembl; ENSNBRT00000028262.1; ENSNBRP00000027544.1; ENSNBRG00000021019.1.
DR GeneID; 102776285; -.
DR CTD; 23336; -.
DR GeneTree; ENSGT00940000159268; -.
DR OMA; KMLYASE; -.
DR OrthoDB; 5353519at2759; -.
DR Proteomes; UP000261580; Unplaced.
DR Bgee; ENSNBRG00000021019; Expressed in muscle tissue and 7 other cell types or tissues.
DR GO; GO:0005882; C:intermediate filament; IEA:UniProtKB-KW.
DR GO; GO:0005200; F:structural constituent of cytoskeleton; IEA:InterPro.
DR GO; GO:0008307; F:structural constituent of muscle; IEA:InterPro.
DR GO; GO:0045104; P:intermediate filament cytoskeleton organization; IEA:InterPro.
DR Gene3D; 1.20.5.170; -; 1.
DR Gene3D; 1.20.5.1160; Vasodilator-stimulated phosphoprotein; 1.
DR InterPro; IPR018039; IF_conserved.
DR InterPro; IPR039008; IF_rod_dom.
DR InterPro; IPR030634; SYNM.
DR PANTHER; PTHR47136; SYNEMIN; 1.
DR PANTHER; PTHR47136:SF1; SYNEMIN; 1.
DR Pfam; PF00038; Filament; 1.
DR SMART; SM01391; Filament; 1.
DR SUPFAM; SSF64593; Intermediate filament protein, coiled coil region; 2.
DR PROSITE; PS00226; IF_ROD_1; 1.
DR PROSITE; PS51842; IF_ROD_2; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Intermediate filament {ECO:0000256|ARBA:ARBA00022754,
KW ECO:0000256|RuleBase:RU000685};
KW Reference proteome {ECO:0000313|Proteomes:UP000261580}.
FT DOMAIN 11..318
FT /note="IF rod"
FT /evidence="ECO:0000259|PROSITE:PS51842"
FT REGION 412..500
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 678..751
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 8..49
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 111..152
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 202..289
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 412..444
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 462..486
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 680..696
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 697..713
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 714..729
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1020 AA; 115816 MW; 30B81A12F065F8A2 CRC64;
MLPFKRTFES EKHQLQELNS RLTQYLSRTK QLEQENAHLI AEINKLRQVR TTGWETKYRA
EMQDLRRMVG QLSFEKSQAE MEREKLWREL QMIQSLCSEQ TDVCRDVSGE LKNCEQELHH
AHKTNSELQQ RLLQLENEYK RLEDAHREEV SRLCRQVESR VAPIIRQTYR GPPVVSVEEV
QEYAHGMSEG WIQTFEMYQK TVEDMEQSIK ADQAMLNDMQ REKMLYASEL DKLRTEAEKQ
GQIQMRLEEQ LMHMQEKFRV DYSQYQMTIE QLEHERNVMA DVIAQKMREH QQLLQVKMDL
GMEVATYRAL LEGERISLQD AHKRGNQHQR ERIIDIKMPA QRYTPRASTL TTKQHMDIRY
MPSTSSLRRA PIPSSGSISP SRVIPISVTG RARHQSPASR RDMISFNKAR AAASATTITT
TSTTTKDKQA GHSENQVSRS VPKRTAEEQT VKLIWLPHTE GQMSPDKSST PDTKSVRVVS
PSMKVTETET ESKKYVSDEK EKGPVVEGEV KDKGRTEFTI GPAEKKILDS VSVEEIIEKV
IKPAGLEGKD CSAGDSKVRY HVEKTEQEDG TTKTQIVLES KVEEELDVSQ DNALEELLKQ
GVKKVSLEDI KDTATGSMVK NLLSGLQGGE DLQNKSFNVE IIEEPVESYS DEELEAEQKS
GFTFHEPSAY FQVEEPENIP HGFQDSRGDD NVMKSNTDES KFGSVQVQEV SRESEFPHFS
HDQESHEYFV STPDENLSES EEGGGITSYG HYGIVDDLSD ERYYQDDGLP QKKVTVKESD
EYEFMSGDRL FAKESFPECI IEEEVRVSPI VQESVLEYLR EDSLEPKEQL KGALEKLQSS
VSGPLKEELA FLTRVSSESP ENVAVDVKRV KQSTDNGTMT IVAELNVSQT LEESGLLEGD
DLSEDQIMAA LKSSNMGIEK AFQSGAGGGY SIRVSREDNV ADSVEYGNFS DKGESASEIG
EKHFKLGPSD KSFSFQMDVH GGHDEAASEQ ELQPPVLEMP VKISQEKRIA TVYLESPSND
//
