ID A0A3Q7FR67_SOLLC Unreviewed; 360 AA.
AC A0A3Q7FR67;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=Vignain {ECO:0008006|Google:ProtNLM};
GN Name=101252974 {ECO:0000313|EnsemblPlants:Solyc03g111730.3.1};
OS Solanum lycopersicum (Tomato) (Lycopersicon esculentum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum;
OC Solanum subgen. Lycopersicon.
OX NCBI_TaxID=4081 {ECO:0000313|EnsemblPlants:Solyc03g111730.3.1};
RN [1] {ECO:0000313|EnsemblPlants:Solyc03g111730.3.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Heinz 1706 {ECO:0000313|EnsemblPlants:Solyc03g111730.3.1};
RX PubMed=22660326; DOI=10.1038/nature11119;
RG Tomato Genome Consortium;
RT "The tomato genome sequence provides insights into fleshy fruit
RT evolution.";
RL Nature 485:635-641(2012).
RN [2] {ECO:0000313|EnsemblPlants:Solyc03g111730.3.1}
RP IDENTIFICATION.
RC STRAIN=cv. Heinz 1706 {ECO:0000313|EnsemblPlants:Solyc03g111730.3.1};
RG EnsemblPlants;
RL Submitted (JAN-2019) to UniProtKB.
CC -!- SIMILARITY: Belongs to the peptidase C1 family.
CC {ECO:0000256|ARBA:ARBA00008455}.
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DR RefSeq; NP_001316891.1; NM_001329962.1.
DR AlphaFoldDB; A0A3Q7FR67; -.
DR STRING; 4081.A0A3Q7FR67; -.
DR PaxDb; 4081-Solyc03g111730-2-1; -.
DR EnsemblPlants; Solyc03g111730.3.1; Solyc03g111730.3.1; Solyc03g111730.3.
DR GeneID; 101252974; -.
DR Gramene; Solyc03g111730.3.1; Solyc03g111730.3.1; Solyc03g111730.3.
DR KEGG; sly:101252974; -.
DR InParanoid; A0A3Q7FR67; -.
DR OMA; GKCDASK; -.
DR OrthoDB; 5472443at2759; -.
DR Proteomes; UP000004994; Chromosome 3.
DR GO; GO:0005615; C:extracellular space; IBA:GO_Central.
DR GO; GO:0004197; F:cysteine-type endopeptidase activity; IBA:GO_Central.
DR GO; GO:0051603; P:proteolysis involved in protein catabolic process; IBA:GO_Central.
DR CDD; cd02248; Peptidase_C1A; 1.
DR Gene3D; 3.90.70.10; Cysteine proteinases; 1.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR InterPro; IPR025661; Pept_asp_AS.
DR InterPro; IPR000169; Pept_cys_AS.
DR InterPro; IPR025660; Pept_his_AS.
DR InterPro; IPR013128; Peptidase_C1A.
DR InterPro; IPR000668; Peptidase_C1A_C.
DR InterPro; IPR039417; Peptidase_C1A_papain-like.
DR InterPro; IPR013201; Prot_inhib_I29.
DR PANTHER; PTHR12411; CYSTEINE PROTEASE FAMILY C1-RELATED; 1.
DR PANTHER; PTHR12411:SF1001; KDEL-TAILED CYSTEINE ENDOPEPTIDASE CEP1; 1.
DR Pfam; PF08246; Inhibitor_I29; 1.
DR Pfam; PF00112; Peptidase_C1; 1.
DR PRINTS; PR00705; PAPAIN.
DR SMART; SM00848; Inhibitor_I29; 1.
DR SMART; SM00645; Pept_C1; 1.
DR SUPFAM; SSF54001; Cysteine proteinases; 1.
DR PROSITE; PS00640; THIOL_PROTEASE_ASN; 1.
DR PROSITE; PS00139; THIOL_PROTEASE_CYS; 1.
DR PROSITE; PS00639; THIOL_PROTEASE_HIS; 1.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Reference proteome {ECO:0000313|Proteomes:UP000004994};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..360
FT /note="Vignain"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5018614158"
FT DOMAIN 38..93
FT /note="Cathepsin propeptide inhibitor"
FT /evidence="ECO:0000259|SMART:SM00848"
FT DOMAIN 126..342
FT /note="Peptidase C1A papain C-terminal"
FT /evidence="ECO:0000259|SMART:SM00645"
FT REGION 339..360
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 339..353
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 360 AA; 40613 MW; 6095FD484D33D04A CRC64;
MKKLFLVLFT LALVLRLGES FDFHEKELET EEKFWELYER WRSHHTVSRS LDEKHKRFNV
FKANVHYVHN FNKKDKPYKL KLNKFADMTN HEFRQHYAGS KIKHHRTLLG ASRANGTFMY
ANEDNVPPSI DWRKKGAVTP VKDQGQCGSC WAFSTVVAVE GINQIKTKKL VSLSEQELVD
CDTTENQGCN GGLMDPAFDF IKKRGGITTE ERYPYKAEDD KCDIQKRNTP VVSIDGHEDV
PPNDEDALLK AVANQPISVA IDASGSQFQF YSEGVFTGEC GTELDHGVAI VGYGTTVDGT
KYWIVKNSWG AEWGEKGYIR MQRKVDAEEG LCGIAMQPSY PIKTSSNPTG SPAATPKDEL
//
