ID A0A3Q7FRQ8_SOLLC Unreviewed; 274 AA.
AC A0A3Q7FRQ8;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=poly(A)-specific ribonuclease {ECO:0000256|ARBA:ARBA00012161};
DE EC=3.1.13.4 {ECO:0000256|ARBA:ARBA00012161};
GN Name=101244756 {ECO:0000313|EnsemblPlants:Solyc03g117030.2.1.1};
OS Solanum lycopersicum (Tomato) (Lycopersicon esculentum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum;
OC Solanum subgen. Lycopersicon.
OX NCBI_TaxID=4081 {ECO:0000313|EnsemblPlants:Solyc03g117030.2.1.1};
RN [1] {ECO:0000313|EnsemblPlants:Solyc03g117030.2.1.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Heinz 1706
RC {ECO:0000313|EnsemblPlants:Solyc03g117030.2.1.1};
RX PubMed=22660326; DOI=10.1038/nature11119;
RG Tomato Genome Consortium;
RT "The tomato genome sequence provides insights into fleshy fruit
RT evolution.";
RL Nature 485:635-641(2012).
RN [2] {ECO:0000313|EnsemblPlants:Solyc03g117030.2.1.1}
RP IDENTIFICATION.
RC STRAIN=cv. Heinz 1706
RC {ECO:0000313|EnsemblPlants:Solyc03g117030.2.1.1};
RG EnsemblPlants;
RL Submitted (JAN-2019) to UniProtKB.
CC -!- FUNCTION: Ubiquitous transcription factor required for a diverse set of
CC processes. It is a component of the CCR4 complex involved in the
CC control of gene expression. {ECO:0000256|ARBA:ARBA00025148}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Exonucleolytic cleavage of poly(A) to 5'-AMP.; EC=3.1.13.4;
CC Evidence={ECO:0000256|ARBA:ARBA00001663};
CC -!- COFACTOR:
CC Name=a divalent metal cation; Xref=ChEBI:CHEBI:60240;
CC Evidence={ECO:0000256|ARBA:ARBA00001968};
CC -!- SUBUNIT: Component of the CCR4-NOT complex, at least composed of CRR4
CC and CAF1 proteins. {ECO:0000256|ARBA:ARBA00011757}.
CC -!- SIMILARITY: Belongs to the CAF1 family.
CC {ECO:0000256|ARBA:ARBA00008372}.
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DR RefSeq; XP_004235935.1; XM_004235887.3.
DR AlphaFoldDB; A0A3Q7FRQ8; -.
DR STRING; 4081.A0A3Q7FRQ8; -.
DR PaxDb; 4081-Solyc03g117030-1-1; -.
DR EnsemblPlants; Solyc03g117030.2.1; Solyc03g117030.2.1.1; Solyc03g117030.2.
DR GeneID; 101244756; -.
DR Gramene; Solyc03g117030.2.1; Solyc03g117030.2.1.1; Solyc03g117030.2.
DR KEGG; sly:101244756; -.
DR InParanoid; A0A3Q7FRQ8; -.
DR OMA; DFRRNSE; -.
DR OrthoDB; 341493at2759; -.
DR Proteomes; UP000004994; Chromosome 3.
DR GO; GO:0030015; C:CCR4-NOT core complex; IBA:GO_Central.
DR GO; GO:0000932; C:P-body; IBA:GO_Central.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0004535; F:poly(A)-specific ribonuclease activity; IBA:GO_Central.
DR GO; GO:0043928; P:exonucleolytic catabolism of deadenylated mRNA; IBA:GO_Central.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR039637; CNOT7/CNOT8/Pop2.
DR InterPro; IPR006941; RNase_CAF1.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR PANTHER; PTHR10797; CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT; 1.
DR PANTHER; PTHR10797:SF66; POLY(A)-SPECIFIC RIBONUCLEASE; 1.
DR Pfam; PF04857; CAF1; 2.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
PE 3: Inferred from homology;
KW Exonuclease {ECO:0000256|ARBA:ARBA00022839};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW Reference proteome {ECO:0000313|Proteomes:UP000004994};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
SQ SEQUENCE 274 AA; 31176 MW; 7481A5F757EB9E39 CRC64;
MSILPKTDSI HIREVWFDNL EEEFALMREI VDDFPFVAMD TEFPGVVIRP VGNFKNSNDY
HYQTLKDNVD MLKLIQLGLT FSDENGNLPK CGTDKYCIWQ FNFREFNPNE DVFANDSIEL
LRQSGIDFKM NNEKGIDAKH FAELLMSSGI VLNDSVSWVT FHSGYDFGYL LKVLTCQDLP
ETQAGFFTLI NVYFPVIFDI KHLMKFCNSL HGGLNKLAEL LEVERVGICH QAGSDSLLTA
CTFRKLKENF FSGSLDKYAG VLYGLGVENG QSTH
//
