ID A0A3Q7FU74_SOLLC Unreviewed; 983 AA.
AC A0A3Q7FU74;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=Ribonuclease {ECO:0000256|PIRNR:PIRNR017179};
OS Solanum lycopersicum (Tomato) (Lycopersicon esculentum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum;
OC Solanum subgen. Lycopersicon.
OX NCBI_TaxID=4081 {ECO:0000313|EnsemblPlants:Solyc03g118010.3.1};
RN [1] {ECO:0000313|EnsemblPlants:Solyc03g118010.3.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Heinz 1706 {ECO:0000313|EnsemblPlants:Solyc03g118010.3.1};
RX PubMed=22660326; DOI=10.1038/nature11119;
RG Tomato Genome Consortium;
RT "The tomato genome sequence provides insights into fleshy fruit
RT evolution.";
RL Nature 485:635-641(2012).
RN [2] {ECO:0000313|EnsemblPlants:Solyc03g118010.3.1}
RP IDENTIFICATION.
RC STRAIN=cv. Heinz 1706 {ECO:0000313|EnsemblPlants:Solyc03g118010.3.1};
RG EnsemblPlants;
RL Submitted (JAN-2019) to UniProtKB.
CC -!- FUNCTION: Cytoprotective ribonuclease (RNase) required for resistance
CC to abiotic stresses, acting as a positive regulator of mRNA decapping
CC during stress. {ECO:0000256|PIRNR:PIRNR017179}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|PIRNR:PIRNR017179}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; A0A3Q7FU74; -.
DR STRING; 4081.A0A3Q7FU74; -.
DR PaxDb; 4081-Solyc03g118010-2-1; -.
DR EnsemblPlants; Solyc03g118010.3.1; Solyc03g118010.3.1; Solyc03g118010.3.
DR Gramene; Solyc03g118010.3.1; Solyc03g118010.3.1; Solyc03g118010.3.
DR InParanoid; A0A3Q7FU74; -.
DR OMA; EKTCCTV; -.
DR Proteomes; UP000004994; Chromosome 3.
DR GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0016442; C:RISC complex; IEA:UniProtKB-UniRule.
DR GO; GO:0004518; F:nuclease activity; IBA:GO_Central.
DR GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR GO; GO:0006402; P:mRNA catabolic process; IBA:GO_Central.
DR GO; GO:0031047; P:regulatory ncRNA-mediated gene silencing; IEA:InterPro.
DR CDD; cd20443; Tudor_AtTudor1-like; 1.
DR Gene3D; 2.30.30.140; -; 1.
DR Gene3D; 2.40.50.90; -; 5.
DR InterPro; IPR016685; Silence_cplx_Nase-comp_TudorSN.
DR InterPro; IPR035437; SNase_OB-fold_sf.
DR InterPro; IPR016071; Staphylococal_nuclease_OB-fold.
DR InterPro; IPR002999; Tudor.
DR InterPro; IPR047395; Tudor_AtTudor1-like.
DR PANTHER; PTHR12302; EBNA2 BINDING PROTEIN P100; 1.
DR PANTHER; PTHR12302:SF2; STAPHYLOCOCCAL NUCLEASE DOMAIN-CONTAINING PROTEIN 1; 1.
DR Pfam; PF00565; SNase; 5.
DR Pfam; PF00567; TUDOR; 1.
DR PIRSF; PIRSF017179; RISC-Tudor-SN; 1.
DR SMART; SM00318; SNc; 4.
DR SMART; SM00333; TUDOR; 1.
DR SUPFAM; SSF50199; Staphylococcal nuclease; 5.
DR SUPFAM; SSF63748; Tudor/PWWP/MBT; 1.
DR PROSITE; PS50830; TNASE_3; 4.
DR PROSITE; PS50304; TUDOR; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|PIRNR:PIRNR017179};
KW Reference proteome {ECO:0000313|Proteomes:UP000004994};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 5..143
FT /note="TNase-like"
FT /evidence="ECO:0000259|PROSITE:PS50830"
FT DOMAIN 178..358
FT /note="TNase-like"
FT /evidence="ECO:0000259|PROSITE:PS50830"
FT DOMAIN 372..548
FT /note="TNase-like"
FT /evidence="ECO:0000259|PROSITE:PS50830"
FT DOMAIN 578..705
FT /note="TNase-like"
FT /evidence="ECO:0000259|PROSITE:PS50830"
FT DOMAIN 776..841
FT /note="Tudor"
FT /evidence="ECO:0000259|PROSITE:PS50304"
FT REGION 134..156
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 229..256
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 937..983
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 983 AA; 108213 MW; 6667166463B538D1 CRC64;
MASTGWLKGR VKAVPSGDSL VIMGSSKAEI PPEKSITLGS LMAPRLARRG GVDEPFAWQS
RDFLRKLCIG KEVTFKVEYA VPSIGREYGT VFVGDKNVSM LVVAAGWAKV REQGQQKDAN
PYLKQLQDAE EQAKQQGLGR WSRAPGASEA SIRNLPPSAI GDASNFDAMG LLERSKGKLI
EAFVEQVRDG STLRVYLLPE FQFIQVFVAG IQAPTMGRRA TSETIINTRV TSDEPNGESI
TEPRATPTSA QRLASSAASV TEVSPDSYGR EAKHFTETCV LNRDVRIVLE GVDKYSNLIG
SVYYPDGESA KDLGLELIEN VYAKYVDWSA NMLEGEAKKK LKNAELEAKK TRLRIWTNYV
APATNSKAIH DQNFTGKVVE VVSGDCLVIA DDSLPFGDPS AERRVNLSSI RSPKMGNPRR
DEKPAPYARE AKEFLRNRLI GKQVHVSMEY SRKVNMADGP AAPASSADSR VMDFGTVFLA
SKDGDDASPA PSAAGNQLAG VNVAELLVAR GFATVVRHRD FEERSNYYDA LLSAESRATS
GKKGIHSPKE APVMHVTDLL TAASKKARDF LPFLQRNRRM SAVVEYVLSG HRFKLFIPKE
TCSIAFSISG VRCPGREEPY SEEAIALMRR KIMQRDVEIE VETVDRTGTF IGTLWESRSN
VAVTLLEAGL ARLQTSFGAD RIPEVHLLLQ AEQAAKRQKL KARASYIWEN YVEGEEVVSS
GAADRRQKEE LKVTVTEILG EGKFYVQLVS DQKVAAIQKQ LASLNLQEAP VIGAFNPKKG
DIVLAQFSAD NSWNRAMIVN APRGAVESSK DKFEVFYVDY GNQEVVSYSQ LRPLEASVSS
SPGLAQLCSL AHVKVPGLED DYGQEAAYRL SELLLSGPKE FKAVIEEKDT SGGKVKGQGT
GTIFLVTLVD PESDVSVNAT LLKEGLARME KRKRWVPKDK QEALDELEKH QTEAREKRRA
MWEYGDVESD EEDIPARKPA GKR
//
