ID A0A3Q7FWM7_SOLLC Unreviewed; 428 AA.
AC A0A3Q7FWM7;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=AAA+ ATPase domain-containing protein {ECO:0000259|SMART:SM00382};
GN Name=101268371 {ECO:0000313|EnsemblPlants:Solyc03g123730.3.1};
OS Solanum lycopersicum (Tomato) (Lycopersicon esculentum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum;
OC Solanum subgen. Lycopersicon.
OX NCBI_TaxID=4081 {ECO:0000313|EnsemblPlants:Solyc03g123730.3.1};
RN [1] {ECO:0000313|EnsemblPlants:Solyc03g123730.3.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Heinz 1706 {ECO:0000313|EnsemblPlants:Solyc03g123730.3.1};
RX PubMed=22660326; DOI=10.1038/nature11119;
RG Tomato Genome Consortium;
RT "The tomato genome sequence provides insights into fleshy fruit
RT evolution.";
RL Nature 485:635-641(2012).
RN [2] {ECO:0000313|EnsemblPlants:Solyc03g123730.3.1}
RP IDENTIFICATION.
RC STRAIN=cv. Heinz 1706 {ECO:0000313|EnsemblPlants:Solyc03g123730.3.1};
RG EnsemblPlants;
RL Submitted (JAN-2019) to UniProtKB.
CC -!- FUNCTION: The 26S proteasome is involved in the ATP-dependent
CC degradation of ubiquitinated proteins. The regulatory (or ATPase)
CC complex confers ATP dependency and substrate specificity to the 26S
CC complex. {ECO:0000256|ARBA:ARBA00024661}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the AAA ATPase family.
CC {ECO:0000256|ARBA:ARBA00006914, ECO:0000256|RuleBase:RU003651}.
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DR RefSeq; XP_004235518.1; XM_004235470.3.
DR AlphaFoldDB; A0A3Q7FWM7; -.
DR STRING; 4081.A0A3Q7FWM7; -.
DR PaxDb; 4081-Solyc03g123730-2-1; -.
DR EnsemblPlants; Solyc03g123730.3.1; Solyc03g123730.3.1; Solyc03g123730.3.
DR GeneID; 101268371; -.
DR Gramene; Solyc03g123730.3.1; Solyc03g123730.3.1; Solyc03g123730.3.
DR KEGG; sly:101268371; -.
DR InParanoid; A0A3Q7FWM7; -.
DR OMA; INGYKKF; -.
DR OrthoDB; 5488626at2759; -.
DR Proteomes; UP000004994; Chromosome 3.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0008540; C:proteasome regulatory particle, base subcomplex; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0036402; F:proteasome-activating activity; IBA:GO_Central.
DR GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; IBA:GO_Central.
DR CDD; cd19502; RecA-like_PAN_like; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR041569; AAA_lid_3.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR003960; ATPase_AAA_CS.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR048723; PRS7-like_OB.
DR PANTHER; PTHR23073; 26S PROTEASOME REGULATORY SUBUNIT; 1.
DR PANTHER; PTHR23073:SF173; 26S PROTEASOME REGULATORY SUBUNIT 7 HOMOLOG A; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF17862; AAA_lid_3; 1.
DR Pfam; PF21236; PRS7_OB; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00674; AAA; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|RuleBase:RU003651};
KW Nucleotide-binding {ECO:0000256|RuleBase:RU003651};
KW Proteasome {ECO:0000256|ARBA:ARBA00022942};
KW Reference proteome {ECO:0000313|Proteomes:UP000004994}.
FT DOMAIN 203..342
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 428 AA; 47874 MW; 29F8F3E216F42545 CRC64;
MAPAADVEDE IKDEKNPRPL DEDDIALLKT YGLGPYSTSI KKCEKEIKEM AKKINDLCGI
KESDTGLAVP SQWDLVSDKQ MMQEEQPLQV ARCTKIISPN TEDAKYVINV KQIAKFVVGL
GDKVSPTDIE EGMRVGVDRN KYQIQIPLPP KIDPSVTMMT VEEKPDVTYN DVGGCKEQIE
KMREVVELPM LHPEKFVKLG IDPPKGVLCY GPPGTGKTLL ARAVANRTDA CFIRVIGSEL
VQKYVGEGAR MVRELFQMAR SKKACIVFFD EVDAIGGARF DDGVGGDNEV QRTMLEIVNQ
LDGFDARGNI KVLMATNRPD TLDPALLRPG RLDRKVEFGL PDLESRTQIF KIHTRTMNCE
RDIRFELLAR LCPNSTGADI RSVCTEAGMY AIRARRKTVT EKDFLDAVNK VIKGYQKFSA
TPKYMVYN
//
